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Ring Finger Protein 43 Proteins (RNF43)

RNF43 is a HAP95 (AKAP8L\; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004 [PubMed 15492824]\; Sugiura et al., 2008 [PubMed 18313049]).[supplied by OMIM, Dec 2008].. Additionally we are shipping RNF43 Antibodies (23) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
RNF43 54894 Q68DV7
RNF43 207742 Q5NCP0
Rat RNF43 RNF43 303412  
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Top RNF43 Proteins at antibodies-online.com

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$382.80
Details

RNF43 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Ring Finger Protein 43 (RNF43) Interaction Partners

Human Ring Finger Protein 43 (RNF43) interaction partners

  1. Authors also identified ring finger (show PCGF1 Proteins) 43 (RNF43), an inhibitor of Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling, as a target of miR (show MLXIP Proteins)-550a-5p.

  2. RNF43 inhibits the Wnt (show WNT2 Proteins) pathway downstream of oncogenic mutations that activate the pathway.

  3. RNF43 might act as a tumor suppressor in gastric carcinoma and might be a potential indicator for the clinical assessment of gastric cancer prognosis

  4. RNF43 gene harbored not only exceedingly high mutations but also mutational intratumoral heterogeneity, which together might play a role in tumorigenesis of gastric and colorectal cancers.

  5. The nucleoprotein of influenza A virus targets RNF43 to modulate p53 (show TP53 Proteins) ubiquitination levels and hence causes p53 (show TP53 Proteins) stabilization which is conducive to an enhanced apoptosis level in the host cells.

  6. we found that the decreased expression of RNF43 in glioma was associated with poor prognosis by the Kaplan-Meier survival analysis. Importantly, multivariate analysis suggested RN43 as an independent predictor of overall survival.

  7. These results indicate that RNF43 mutation might cause downregulation of the expression of ring finger protein 43 and play a crucial role during development of intraductal papillary mucinous neoplasm of the pancreas.

  8. Data indicate Dishevelled (DVL (show DVL2 Proteins)) as a dual function adaptor to recruit negative regulators ZNRF3 (show ZNRF3 Proteins)/RNF43 to Wnt (show WNT2 Proteins) receptors to ensure proper control of pathway activity.

  9. Missense mutations of RNF43 change their localization from the endosome to the endoplasmic reticulum.

  10. RNF43 is one of the most commonly mutated genes in colorectal and endometrial cancers

Mouse (Murine) Ring Finger Protein 43 (RNF43) interaction partners

  1. RNF43 and ZNRF3 (show ZNRF3 Proteins) reduce Wnt (show WNT2 Proteins) signals by selectively ubiquitinating frizzled receptors, thereby targeting these Wnt (show WNT2 Proteins) receptors for degradation

RNF43 Protein Profile

Protein Summary

RNF43 is a HAP95 (AKAP8L\; MIM 609475) binding ubiquitin ligase that promotes cell growth and is upregulated in colon cancer (Yagyu et al., 2004

Gene names and symbols associated with Ring Finger Protein 43 Proteins (RNF43)

  • ring finger protein 43 (RNF43)
  • ring finger protein 43 (Rnf43)
  • 4732452J19Rik protein
  • RGD1305204 protein
  • RNF124 protein
  • URCC protein

Protein level used designations for Ring Finger Protein 43 Proteins (RNF43)

E3 ubiquitin-protein ligase RNF43 , RING finger protein 43

GENE ID SPECIES
100057001 Equus caballus
54894 Homo sapiens
491114 Canis lupus familiaris
784035 Bos taurus
207742 Mus musculus
303412 Rattus norvegicus
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