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Ring Finger and FYVE-Like Domain Containing 1 (RFFL) ELISA Kits

Has E3 ubiquitin protein ligase activity. Additionally we are shipping RFFL Antibodies (64) and RFFL Proteins (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse RFFL RFFL 67338 Q6ZQM0
Anti-Human RFFL RFFL 117584 Q8WZ73
Anti-Rat RFFL RFFL 282844 Q8CIN9
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More ELISA Kits for RFFL Interaction Partners

Mouse (Murine) Ring Finger and FYVE-Like Domain Containing 1 (RFFL) interaction partners

  1. EGF (show EGF ELISA Kits), which signals through CRAF (show RAF1 ELISA Kits), and an activated BRAF (show BRAF ELISA Kits) mutant also activate PKC (show PKC ELISA Kits) and stimulate cell migration through up-regulating RFFL expression.

  2. Data show that the the amino-terminal domain of rififylin is critical for its recruitment to recycling endocytic membranes and for the inhibition of recycling.

  3. CARP2 (show CA11 ELISA Kits) [Rififylin] deficiency does not alter induction of NF-kappaB (show NFKB1 ELISA Kits) by TNFalpha (show TNF ELISA Kits).

Human Ring Finger and FYVE-Like Domain Containing 1 (RFFL) interaction partners

  1. EGF (show EGF ELISA Kits), which signals through CRAF (show RAF1 ELISA Kits), and an activated BRAF (show BRAF ELISA Kits) mutant also activate PKC and stimulate cell migration through up-regulating RFFL expression.

  2. data indicate AE induces caspase-8 (show CASP8 ELISA Kits)-mediated activation of mitochondrial death pathways by decreasing the stability of CARP (show CA8 ELISA Kits) mRNAs in a p53 (show TP53 ELISA Kits)-independent manner.

  3. CARPs together with MDM2 (show MDM2 ELISA Kits) enhance p53 (show TP53 ELISA Kits) degradation, thereby inhibiting p53 (show TP53 ELISA Kits)-mediated cell death.

  4. acts at the level of endocytic vesicles to limit the intensity of TNF (show TNF ELISA Kits)-induced NF-kappaB (show NFKB1 ELISA Kits) activation by the regulated elimination of a necessary signaling component within the receptor complex

RFFL Antigen Profile

Antigen Summary

Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates (By similarity). Overexpression slows protein traffic through recycling endosomes.

Gene names and symbols associated with RFFL

  • ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (RFFL) antibody
  • ring finger and FYVE-like domain containing 1 (rffl) antibody
  • ring finger and FYVE-like domain containing 1 (RFFL) antibody
  • ring finger and FYVE-like domain containing 1 (Rffl) antibody
  • ring finger and FYVE like domain containing protein (Rffl) antibody
  • ring finger and FYVE-like domain containing E3 ubiquitin protein ligase (Rffl) antibody
  • 1700051E09Rik antibody
  • 4930516L10Rik antibody
  • BG080975 antibody
  • CARP-2 antibody
  • CARP2 antibody
  • FRING antibody
  • MGC84042 antibody
  • Rffl antibody
  • RIFIFYLIN antibody
  • RNF34L antibody
  • RNF189 antibody

Protein level used designations for RFFL

E3 ubiquitin-protein ligase rififylin , ring finger and FYVE-like domain containing 1 , rififylin , e3 ubiquitin-protein ligase rififylin-like , RING finger and FYVE-like domain-containing protein 1 , fring , FYVE-RING finger protein SAKURA , RING finger protein 189 , caspase regulator CARP2 , caspases-8 and -10-associated RING finger protein 2 , FYVE-RING finger protein Sakura , RING finger protein SAKURA , ring finger and FYVE like domain containing protein

GENE ID SPECIES
417529 Gallus gallus
447349 Xenopus laevis
454582 Pan troglodytes
491144 Canis lupus familiaris
530263 Bos taurus
100058179 Equus caballus
100115488 Nasonia vitripennis
100464760 Ailuropoda melanoleuca
100604408 Nomascus leucogenys
67338 Mus musculus
117584 Homo sapiens
282844 Rattus norvegicus
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