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anti-Ring Finger and WD Repeat Domain 3 (RFWD3) Antibodies

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. Additionally we are shipping RFWD3 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RFWD3 361409  
RFWD3 55159 Q6PCD5
RFWD3 234736 Q8CIK8
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Top anti-RFWD3 Antibodies at antibodies-online.com

Showing 10 out of 25 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from MCF-7 cells, using RFWD3 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IHC, WB Immunohistochemical analysis of RFWD3 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugad compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of RFWD3 expression in HeLa (A), HepG2 (B) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.63 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$595.83
Details

RFWD3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Human , ,
,
,
Mouse (Murine)


Top referenced anti-RFWD3 Antibodies

  1. Human Polyclonal RFWD3 Primary Antibody for ELISA, WB - ABIN1535312 : Matsuoka, Ballif, Smogorzewska, McDonald, Hurov, Luo, Bakalarski, Zhao, Solimini, Lerenthal, Shiloh, Gygi, Elledge: ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. in Science (New York, N.Y.) 2007 (PubMed)

More Antibodies against RFWD3 Interaction Partners

Horse (Equine) Ring Finger and WD Repeat Domain 3 (RFWD3) interaction partners

  1. a polymorphism in the 3'-UTR (show UTS2R Antibodies) of RFWD3 had a strong association with PATN1, which affects spotting patterns in horse coat color

Human Ring Finger and WD Repeat Domain 3 (RFWD3) interaction partners

  1. RFWD3-dependent ubiquitination of RPA regulates repair at stalled replication forks.

  2. RFWD3 and RPA2 (show RPA2 Antibodies) functionally interact and participate in replication checkpoint control

  3. RFWD3 is recruited to sites of DNA damage and facilitates RPA-mediated DNA damage signaling and repair

  4. Study identifies RFWD3 as a positive regulator of p53 (show TP53 Antibodies) stability when the G(1) cell cycle checkpoint is activated and provides an explanation for how p53 (show TP53 Antibodies) is protected from degradation in the presence of high levels of Mdm2 (show MDM2 Antibodies).

RFWD3 Antigen Profile

Protein Summary

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.

Gene names and symbols associated with RFWD3

  • ring finger and WD repeat domain 3 (Rfwd3) antibody
  • ring finger and WD repeat domain 3 (RFWD3) antibody
  • BC027246 antibody
  • RFWD3 antibody
  • RGD1305243 antibody
  • RNF201 antibody

Protein level used designations for RFWD3

ring finger and WD repeat domain 3 , RING finger and WD repeat domain-containing protein 3-like , E3 ubiquitin-protein ligase RFWD3 , RING finger and WD repeat domain-containing protein 3 , RING finger protein 201

GENE ID SPECIES
361409 Rattus norvegicus
415684 Gallus gallus
454242 Pan troglodytes
540072 Bos taurus
610424 Canis lupus familiaris
100055114 Equus caballus
100229473 Taeniopygia guttata
100387225 Callithrix jacchus
100461058 Pongo abelii
55159 Homo sapiens
234736 Mus musculus
Selected quality suppliers for anti-RFWD3 (RFWD3) Antibodies
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