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RFWD3 Proteins

(Ring Finger and WD Repeat Domain 3 (RFWD3))

E3 ubiquitin-protein ligase that mediates the ubiquitination of p53/TP53 in the late response to DNA damage, and acts as a positive regulator of p53/TP53 stability, thereby regulating the G1/S DNA damage checkpoint. May act by catalyzing the formation of short polyubiquitin chains on p53/TP53 that are not targeted to the proteasome. In response to ionizing radiation, interacts with MDM2 and enhances p53/TP53 ubiquitination, possibly by restricting MDM2 from extending polyubiquitin chains on ubiquitinated p53/TP53. Plays a role in RPA-mediated DNA damage signaling and repair.

recommended

RFWD3 Protein (AA 651-749) (GST tag) (ABIN1317874)

RFWD3 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA

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recommended

RFWD3 Protein (AA 1-774) (Strep Tag) (ABIN3094992)

Crystallography grade RFWD3 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

RFWD3 Protein (AA 1-774) (Strep Tag) (ABIN3136488)

Crystallography grade RFWD3 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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RFWD3 Proteins by Grade

Find RFWD3 Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

RFWD3 Proteins by Origin

Find RFWD3 Proteins for a variety of species such as anti-Human RFWD3, anti-Mouse RFWD3. The species listed below are among those available. Click on a link to go to the corresponding products.

RFWD3 Proteins by Source

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RFWD3 Proteins by Protein Type

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RFWD3 Proteins by Application

Find RFWD3 Proteins validated for a specific application such as ELISA, WB, SDS, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular RFWD3 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

RFWD3 Protein (AA 651-749) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1317874

Quantity 10 μg

Datasheet Datasheet

RFWD3 Protein (AA 1-774) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3094992

Quantity 1 mg

Datasheet Datasheet

RFWD3 Protein (AA 1-774) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3136488

Quantity 1 mg

Datasheet Datasheet

Aliases for RFWD3 Proteins

ring finger and WD repeat domain 3 (Rfwd3) Proteins
ring finger and WD repeat domain 3 (RFWD3) Proteins
BC027246 Proteins
RFWD3 Proteins
RGD1305243 Proteins
RNF201 Proteins

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RFWD3 Proteins by Grade

RFWD3 Proteins by Origin

RFWD3 Proteins by Source

RFWD3 Proteins by Protein Type

RFWD3 Proteins by Application

Popular RFWD3 Proteins

Aliases for RFWD3 Proteins

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