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Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Additionally we are shipping ROBO1 Proteins (9) and ROBO1 Kits (5) and many more products for this protein.
Showing 10 out of 93 products:
Dog (Canine) Polyclonal ROBO1 Primary Antibody for EIA, IHC (p) - ABIN401279
Latil, Chêne, Cochant-Priollet, Mangin, Fournier, Berthon, Cussenot: Quantification of expression of netrins, slits and their receptors in human prostate tumors. in International journal of cancer. Journal international du cancer 2002
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Mouse (Murine) Polyclonal ROBO1 Primary Antibody for ELISA, WB - ABIN185724
Andrews, Liapi, Plachez, Camurri, Zhang, Mori, Murakami, Parnavelas, Sundaresan, Richards: Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. in Development (Cambridge, England) 2006
Human Polyclonal ROBO1 Primary Antibody for IP, IHC - ABIN1043879
Li, Wang, Chen, Liang: [Auditory neuropathy in children(analysis of 14 cases)]. in Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 2005
Human Polyclonal ROBO1 Primary Antibody for WB - ABIN265227
Dallol, Forgacs, Martinez, Sekido, Walker, Kishida, Rabbitts, Maher, Minna, Latif: Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. in Oncogene 2002
Human Polyclonal ROBO1 Primary Antibody for ELISA, WB - ABIN185537
Hannula-Jouppi, Kaminen-Ahola, Taipale, Eklund, Nopola-Hemmi, Kääriäinen, Kere: The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. in PLoS genetics 2005
These results demonstrate a key role for Robo-Slit signaling in vertebrate longitudinal axon guidance; Robo1 and Robo3 (show ROBO3 Antibodies) restricted the extent of defasciculation of the tract of the postoptic commissure.
restoration of miR (show MLXIP Antibodies)-218 inhibited retinal angiogenesis via targeting Robo1. MiR (show MLXIP Antibodies)-218 contributed to the inhibition of retinal angiogenesis and miR (show MLXIP Antibodies)-218 might be a new therapeutic target for preventing retinal neovascularization..
In mice with oxygen-induced retinopathy (OIR), the expression level of miR-218 was significantly downregulated. Robo1 expression was suppressed by miR-218. Furthermore, in the mice with OIR, the expression level of miR-218 was significantly downregulated, and that of miR-218-1 and its host gene, Slit2, was concomitantly downregulated as well.
Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.
FLRT3 (show FLRT3 Antibodies) is a Robo1 coreceptor in developing axons.
Slit2 (show SLIT2 Antibodies)/Robo1 signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.
Robo1/2 regulate follicle atresia through manipulating granulosa cell apoptosis in mice
Roundabout receptor (Robo) genes are expressed in pulmonary neuroendocrine cells (PNECs), a rare, innervated epithelial population. Robo inactivation in mouse lung results in an inability of PNECs to cluster into sensory organoids and triggers increased neuropeptide production upon exposure to air.
Slit2 (show SLIT2 Antibodies) signaling through Robo1 and Robo2 (show ROBO2 Antibodies) has a role in retinal neovascularization
Data indicate the roles of Slit1 (show SLIT1 Antibodies)/Robo1 and Netrin1/DCC (show DCC Antibodies) signals in positioning motor neuron cell bodies.
This study demonistrated that significant increase of interneurons in the cortices of Robo1-/- mice, implicate Robo1 in the regulation of progenitor cell dynamics in the developing forebrain.
Over-expression of miR (show MLXIP Antibodies)-218 in glioma cells may inhibit the proliferation and tumorigenicity through targeting Robo1, suggesting that miR (show MLXIP Antibodies)-218 could be a potential target for developing therapies in treating glioma.
Significantly increased serum Slit2 (show SLIT3 Antibodies) levels and hepatic expression of Slit2 (show SLIT3 Antibodies) and Robo1 were observed in patients with liver fibrosis.
our findings indicated that Slit2 (show SLIT3 Antibodies)/Robo1 axis possibly be regarded as a significant clinical parameter for predicting brain metastasis in breast cancer patients.
miR (show MLXIP Antibodies)-29a markedly inhibits the protein expression of Robo1 in mesenchymal stem cells.
A SLIT2 (show SLIT3 Antibodies)/ROBO1 signaling circuit as a key regulatory mechanism.
These results suggest that Slit2 (show SLIT3 Antibodies)/Robo1 binding exerts an effect on cell migration, which is negatively regulated by Robo4 (show ROBO4 Antibodies), and Robo1 may function by interacting with CdGAP (show ARHGAP31 Antibodies) in HUVECs.
ROBO1 somatic mutation is associated with myelodysplastic syndrome progression. Overexpression of ROBO1 produces anti-proliferative and pro-apoptotic effects in leukaemia cells. However, this effect was lost in ROBO mutants.
Robo1 promoted cell division cycle 42 (Cdc42 (show CDC42 Antibodies)) expression in HUVECs, and a distorted actin cytoskeleton in HUVECs was observed when Robo1 expression was suppressed. In conclusion, Robo1 promoted angiogenesis in HCC (show FAM126A Antibodies) mediated by Cdc42 (show CDC42 Antibodies).
Data indicate that SLIT2 (show SLIT3 Antibodies), miR (show MLXIP Antibodies)-218-1, RET (show RET Antibodies)/PLAG1 (show PLAG1 Antibodies) and SLIT2 (show SLIT3 Antibodies)/ROBO1 pathway involved in Hirschsprung's disease.
these studies demonstrate that miR (show MLXIP Antibodies)-219-5p inhibited cancer cell growth and invasion by direct targeting ROBO1, implicating miR (show MLXIP Antibodies)-219-5p as an attractive candidate for cancer therapy.
Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.
roundabout (axon guidance receptor, Drosophila) homolog 1
, roundabout, axon guidance receptor, homolog 1 (Drosophila)
, Roundabout1 protein
, roundabout 1
, roundabout homolog 1
, roundabout, axon guidance receptor, homolog 1
, roundabout homolog 1-like
, divalent metal transporter-1
, protein RoBo-1
, rodent bone protein
, deleted in U twenty twenty