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anti-Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) Antibodies

Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Additionally we are shipping ROBO1 Proteins (9) and ROBO1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ROBO1 24906 O55006
ROBO1 19876 O89026
ROBO1 6091 Q9Y6N7
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Top anti-ROBO1 Antibodies at antibodies-online.com

Showing 10 out of 79 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Goat Un-conjugated EIA, WB AP23652PU-N DUTT1 antibody staining of fetal Mouse Brain lysate at 0.05 µg/ml (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185537 (1µg/ml) staining of HUVEC lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Dog Rabbit Un-conjugated EIA, IHC (p), WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IP, IHC, ELISA, WB Affinity Purified anti-ROBO1 antibody was used at a concentration of 5 µg/ml to detect ROBO1 in a variety of tissues including multi-human, multi-brain and multi-cancer slides. This image shows staining of human brain tissue. Tissue was formalin-fixed and paraffin embedded. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Mouse Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$318.20
Details
Dog Goat Un-conjugated EIA, IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with ROBO1at 2 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Antibody (1 µg/ml) staining of HUVEC lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated ELISA, WB Detection limit for recombinant GST tagged ROBO1 is approximately 0.03 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details

ROBO1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ROBO1 Antibodies

  1. Dog (Canine) Polyclonal ROBO1 Primary Antibody for EIA, IHC (p) - ABIN401279 : Latil, Chêne, Cochant-Priollet, Mangin, Fournier, Berthon, Cussenot: Quantification of expression of netrins, slits and their receptors in human prostate tumors. in International journal of cancer. Journal international du cancer 2002 (PubMed)
    Show all 6 references for ABIN401279

  2. Human Polyclonal ROBO1 Primary Antibody for IP, IHC - ABIN1043879 : Li, Wang, Chen, Liang: [Auditory neuropathy in children(analysis of 14 cases)]. in Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 2005 (PubMed)

  3. Mouse (Murine) Polyclonal ROBO1 Primary Antibody for ELISA, WB - ABIN185724 : Andrews, Liapi, Plachez, Camurri, Zhang, Mori, Murakami, Parnavelas, Sundaresan, Richards: Robo1 regulates the development of major axon tracts and interneuron migration in the forebrain. in Development (Cambridge, England) 2006 (PubMed)

  4. Human Polyclonal ROBO1 Primary Antibody for WB - ABIN265227 : Dallol, Forgacs, Martinez, Sekido, Walker, Kishida, Rabbitts, Maher, Minna, Latif: Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers. in Oncogene 2002 (PubMed)

  5. Dog (Canine) Polyclonal ROBO1 Primary Antibody for WB - ABIN374636 : Hannula-Jouppi, Kaminen-Ahola, Taipale, Eklund, Nopola-Hemmi, Kääriäinen, Kere: The axon guidance receptor gene ROBO1 is a candidate gene for developmental dyslexia. in PLoS genetics 2005 (PubMed)

More Antibodies against ROBO1 Interaction Partners

Zebrafish Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) interaction partners

  1. These results demonstrate a key role for Robo-Slit signaling in vertebrate longitudinal axon guidance; Robo1 and Robo3 (show ROBO3 Antibodies) restricted the extent of defasciculation of the tract of the postoptic commissure.

Mouse (Murine) Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) interaction partners

  1. Robo1-Slit2 interaction required for pathfinding mechanism essential to establish the functionally important habenulo-interpeduncular connection.

  2. FLRT3 (show FLRT3 Antibodies) is a Robo1 coreceptor in developing axons.

  3. Slit2 (show SLIT2 Antibodies)/Robo1 signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

  4. Robo1/2 regulate follicle atresia through manipulating granulosa cell apoptosis in mice

  5. Roundabout receptor (Robo) genes are expressed in pulmonary neuroendocrine cells (PNECs), a rare, innervated epithelial population. Robo inactivation in mouse lung results in an inability of PNECs to cluster into sensory organoids and triggers increased neuropeptide production upon exposure to air.

  6. Slit2 (show SLIT2 Antibodies) signaling through Robo1 and Robo2 (show ROBO2 Antibodies) has a role in retinal neovascularization

  7. Data indicate the roles of Slit1 (show SLIT1 Antibodies)/Robo1 and Netrin1/DCC (show DCC Antibodies) signals in positioning motor neuron cell bodies.

  8. This study demonistrated that significant increase of interneurons in the cortices of Robo1-/- mice, implicate Robo1 in the regulation of progenitor cell dynamics in the developing forebrain.

  9. we report that Robo1 plays an important role in guiding olfactory sensory neurons in the mouse olfactory system during development.

  10. SDF-1-CXCR4 differentially regulates autoimmune diabetogenic T cell adhesion through ROBO1-SLIT2 interactions in mice.

Human Roundabout, Axon Guidance Receptor, Homolog 1 (Drosophila) (ROBO1) interaction partners

  1. Significantly increased serum Slit2 (show SLIT3 Antibodies) levels and hepatic expression of Slit2 (show SLIT3 Antibodies) and Robo1 were observed in patients with liver fibrosis.

  2. our findings indicated that Slit2 (show SLIT3 Antibodies)/Robo1 axis possibly be regarded as a significant clinical parameter for predicting brain metastasis in breast cancer patients.

  3. miR (show MLXIP Antibodies)-29a markedly inhibits the protein expression of Robo1 in mesenchymal stem cells.

  4. A SLIT2 (show SLIT3 Antibodies)/ROBO1 signaling circuit as a key regulatory mechanism.

  5. These results suggest that Slit2 (show SLIT3 Antibodies)/Robo1 binding exerts an effect on cell migration, which is negatively regulated by Robo4 (show ROBO4 Antibodies), and Robo1 may function by interacting with CdGAP (show ARHGAP31 Antibodies) in HUVECs.

  6. ROBO1 somatic mutation is associated with myelodysplastic syndrome progression. Overexpression of ROBO1 produces anti-proliferative and pro-apoptotic effects in leukaemia cells. However, this effect was lost in ROBO mutants.

  7. Robo1 promoted cell division cycle 42 (Cdc42 (show CDC42 Antibodies)) expression in HUVECs, and a distorted actin cytoskeleton in HUVECs was observed when Robo1 expression was suppressed. In conclusion, Robo1 promoted angiogenesis in HCC (show FAM126A Antibodies) mediated by Cdc42 (show CDC42 Antibodies).

  8. Data indicate that SLIT2 (show SLIT3 Antibodies), miR (show MLXIP Antibodies)-218-1, RET (show RET Antibodies)/PLAG1 (show PLAG1 Antibodies) and SLIT2 (show SLIT3 Antibodies)/ROBO1 pathway involved in Hirschsprung's disease.

  9. these studies demonstrate that miR (show MLXIP Antibodies)-219-5p inhibited cancer cell growth and invasion by direct targeting ROBO1, implicating miR (show MLXIP Antibodies)-219-5p as an attractive candidate for cancer therapy.

  10. Slit2 (show SLIT3 Antibodies)/Robo1 signaling promotes intestinal tumorigenesis through Src (show SRC Antibodies)-mediated activation of the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway.

ROBO1 Antigen Profile

Protein Summary

Bilateral symmetric nervous systems have special midline structures that establish a partition between the two mirror image halves. Some axons project toward and across the midline in response to long-range chemoattractants emanating from the midline. The product of this gene is a member of the immunoglobulin gene superfamily and encodes an integral membrane protein that functions in axon guidance and neuronal precursor cell migration. This receptor is activated by SLIT-family proteins, resulting in a repulsive effect on glioma cell guidance in the developing brain. A related gene is located at an adjacent region on chromosome 3. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ROBO1

  • roundabout homolog 1 (robo1) antibody
  • roundabout, axon guidance receptor, homolog 1 (Drosophila) (ROBO1) antibody
  • roundabout, axon guidance receptor, homolog 1 (robo1) antibody
  • roundabout, axon guidance receptor, homolog 1 (Drosophila) (robo1) antibody
  • RoBo-1 (LOC24906) antibody
  • roundabout homolog 1 (Drosophila) (Robo1) antibody
  • roundabout, axon guidance receptor, homolog 1 (Drosophila) (Robo1) antibody
  • AW494633 antibody
  • AW742721 antibody
  • DMT-1 antibody
  • DUTT1 antibody
  • Gm310 antibody
  • MGC122264 antibody
  • ROBO1 antibody
  • roundabout antibody
  • roundabout-1 antibody
  • SAX3 antibody

Protein level used designations for ROBO1

roundabout (axon guidance receptor, Drosophila) homolog 1 , roundabout, axon guidance receptor, homolog 1 (Drosophila) , Roundabout1 protein , roundabout-1 , roundabout 1 , roundabout homolog 1 , roundabout, axon guidance receptor, homolog 1 , roundabout homolog 1-like , divalent metal transporter-1 , protein RoBo-1 , rodent bone protein , deleted in U twenty twenty

GENE ID SPECIES
30769 Danio rerio
395292 Gallus gallus
399392 Xenopus laevis
460518 Pan troglodytes
536815 Bos taurus
722879 Macaca mulatta
100027473 Monodelphis domestica
100069075 Equus caballus
100124716 Xenopus (Silurana) tropicalis
100344245 Oryctolagus cuniculus
100387812 Callithrix jacchus
100459973 Pongo abelii
100517310 Sus scrofa
100545249 Meleagris gallopavo
100559253 Anolis carolinensis
100595092 Nomascus leucogenys
24906 Rattus norvegicus
19876 Mus musculus
6091 Homo sapiens
58946 Rattus norvegicus
487690 Canis lupus familiaris
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