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anti-Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila) (ROBO2) Antibodies

ROBO2 belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. Additionally we are shipping ROBO2 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ROBO2 268902  
ROBO2 6092 Q9HCK4
ROBO2 84409  
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Top anti-ROBO2 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-ROBO2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using ROBO2 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated ELISA, WB 0.05 mg Log in to see 8 to 11 Days
$450.00
Details
Dog Goat Un-conjugated EIA, IHC (p) 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated IHC (p), WB Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Goat Un-conjugated IHC (p), ELISA Human Testis (formalin-fixed, paraffin-embedded) stained with ROBO2 antibody ABIN337029 at 5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Chicken Rabbit Un-conjugated WB Western blot analysis of ROBO2 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

ROBO2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ROBO2 Antibodies

  1. Human Monoclonal ROBO2 Primary Antibody for ELISA, WB - ABIN393348 : Rose, Behm, Drgon, Johnson, Uhl: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. in Molecular medicine (Cambridge, Mass.) 2010 (PubMed)
    Show all 5 references for ABIN393348

  2. Chicken Polyclonal ROBO2 Primary Antibody for WB - ABIN2782202 : Bertoli-Avella, Conte, Punzo, de Graaf, Lama, La Manna, Polito, Grassia, Nobili, Rambaldi, Oostra, Perrotta: ROBO2 gene variants are associated with familial vesicoureteral reflux. in Journal of the American Society of Nephrology : JASN 2008 (PubMed)

  3. Human Polyclonal ROBO2 Primary Antibody for ELISA, WB - ABIN334482 : Fujisawa, Wrana, Culotti: The slit receptor EVA-1 coactivates a SAX-3/Robo mediated guidance signal in C. elegans. in Science (New York, N.Y.) 2007 (PubMed)

  4. Human Polyclonal ROBO2 Primary Antibody for IHC, ELISA - ABIN1535320 : Kidd, Brose, Mitchell, Fetter, Tessier-Lavigne, Goodman, Tear: Roundabout controls axon crossing of the CNS midline and defines a novel subfamily of evolutionarily conserved guidance receptors. in Cell 1998 (PubMed)

More Antibodies against ROBO2 Interaction Partners

Zebrafish Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila) (ROBO2) interaction partners

  1. Genetic analysis showed that Caspase-3 (show CASP3 Antibodies), Caspase-9 (show CASP9 Antibodies), and p38 MAPK (show MAPK14 Antibodies) interacted with Slit1a-Robo2 signaling.

  2. The N-terminal domain unique to Robo3a (show ROBO3 Antibodies).1 mediates blockade of Robo2 repulsive activity.

  3. Robo2-Slit and Dcc (show DCC Antibodies)-Netrin1 coordinate the axonal projection choices of neurons developing in the forebrain.

  4. These results reveal that subtype-specific activity of Robo2 regulates subcircuit morphogenesis in the trigeminal sensory system.

  5. Increased arborization in robo2 mutants was phenocopied by dominant-negative Robo2 expressed in single retinal ganglion cells and rescued by full-length Robo2, indicating that Robo2 acts cell-autonomously.

  6. Robo2 acted initially to split the tract of the postoptic commissure into discrete fascicles upon entering a broad domain of Slit1a expression in the ventrocaudal diencephalon.

Mouse (Murine) Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila) (ROBO2) interaction partners

  1. Robo1 (show ROBO1 Antibodies)/2 regulate follicle atresia through manipulating granulosa cell apoptosis in mice

  2. Roundabout receptor (Robo) genes are expressed in pulmonary neuroendocrine cells (PNECs), a rare, innervated epithelial population. Robo inactivation in mouse lung results in an inability of PNECs to cluster into sensory organoids and triggers increased neuropeptide production upon exposure to air.

  3. Loss of Robo2 resulted in a failure of the normal separation of the mesenchyme from the Wolffian duct/ureteric epithelium.

  4. Mutations of the SLIT2 (show SLIT2 Antibodies)-ROBO2 pathway genes SLIT2 (show SLIT2 Antibodies) and SRGAP1 (show SRGAP1 Antibodies) confer risk for congenital anomalies of the kidney and urinary tract

  5. Slit2 (show SLIT2 Antibodies) signaling through Robo1 (show ROBO1 Antibodies) and Robo2 has a role in retinal neovascularization

  6. Mycbp2 (show MYCBP2 Antibodies) and Robo2 were found to cooperate within a genetic network that has profound effects on axon guidance

  7. Report role of Robo2 in development of the caval veins and pericardium.

  8. Inactivation of Robo 2 leads to mispositioning of the stomach in the thoracic instead of the abdominal cavity, which likely contributes to poor lung inflation and lethality at birth, reminiscent of congenital diaphragmatic hernia.

  9. Robo2 signaling acts as a negative regulator on nephrin (show NPHS1 Antibodies) to influence podocyte foot process architecture.

  10. Gbx2 (show GBX2 Antibodies) regulates thalamocortical axon guidance by modifying the LIM (show PDLIM5 Antibodies) and Robo codes.

Human Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila) (ROBO2) interaction partners

  1. Overexpression of ROBO2 induces its tumor suppressive effects in Breast cancer

  2. ROBO2 somatic mutation is associated with myelodysplastic syndrome progression. Overexpression of ROBO2 produces anti-proliferative and pro-apoptotic effects in leukemia cells. This effect was lost in ROBO mutants and ROBO-SLIT2 signaling is impaired.

  3. Common variation near ROBO2 is associated with expressive vocabulary in infancy.

  4. Mutations of the SLIT2 (show SLIT3 Antibodies)-ROBO2 pathway genes SLIT2 (show SLIT3 Antibodies) and SRGAP1 (show SRGAP1 Antibodies) confer risk for congenital anomalies of the kidney and urinary tract

  5. Down-regulation of ROBO2 expression is associated with prostate cancers.

  6. Frameshift mutations of ROBO1 (show ROBO1 Antibodies) and ROBO2 genes and alteration of ROBO2 expression in gastric and colorectal cancers suggest that both genes might play roles in the pathogenesis of both cancers.

  7. The finding that a polymorphism associated with the ROBO2 gene, which is involved in neurodevelopment, confers risk for the common emotionally reactive, impulsive aspects of conduct disorder, independent of concurrent risk for psychopathy.

  8. Results not completely rule out that some ROBO2 variants may be the sole cause of vesicoureteric reflux, but it is clear from the overall frequency that most of them cannot be.

  9. data suggests the importance of abrogation of SLIT2 (show SLIT3 Antibodies)-ROBO1 (show ROBO1 Antibodies) and SLIT2 (show SLIT3 Antibodies)-ROBO2 interactions in the initiation and progression of CACX and also for early diagnosis and prognosis of the disease

  10. Disruption of ROBO2 is associated with urinary tract anomalies and confers risk of vesicoureteral reflux.

ROBO2 Antigen Profile

Protein Summary

This gene belongs to the ROBO family, part of the immunoglobulin superfamily proteins that are highly conserved from fly to human. The encoded protein is a receptor for SLIT2, molecules known to function in axon guidance and cell migration. Defects in this gene are the cause of vesicoureteral reflux type 2. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with ROBO2

  • roundabout, axon guidance receptor, homolog 2 (Drosophila) (ROBO2) antibody
  • roundabout, axon guidance receptor, homolog 2 (Drosophila) (LOC100221297) antibody
  • roundabout, axon guidance receptor, homolog 2 (Drosophila) (robo2) antibody
  • roundabout homolog 2 (robo2) antibody
  • roundabout homolog 2 (Drosophila) (Robo2) antibody
  • roundabout homolog 2-like (LOC534842) antibody
  • roundabout, axon guidance receptor, homolog 2 (robo2) antibody
  • roundabout, axon guidance receptor, homolog 2 (Drosophila) (Robo2) antibody
  • 2600013A04Rik antibody
  • 9430089E08Rik antibody
  • BB097918 antibody
  • D230004I22Rik antibody
  • mKIAA1568 antibody
  • ROBO2 antibody
  • SAX3 antibody
  • unp1881 antibody

Protein level used designations for ROBO2

roundabout, axon guidance receptor, homolog 2 (Drosophila) , roundabout homolog 2-like , ast , astray , zmp:0000000549 , roundabout homolog 2 , roundabout, axon guidance receptor, homolog 2 , Robo 2 , roundabout-2 , roundabout 2 precursor , Roundabout2 protein

GENE ID SPECIES
100068957 Equus caballus
460517 Pan troglodytes
100221297 Taeniopygia guttata
100388667 Callithrix jacchus
100493913 Xenopus (Silurana) tropicalis
100545405 Meleagris gallopavo
100567276 Anolis carolinensis
60309 Danio rerio
268902 Mus musculus
534842 Bos taurus
100462919 Xenopus laevis
6092 Homo sapiens
487691 Canis lupus familiaris
84409 Rattus norvegicus
395291 Gallus gallus
100739586 Sus scrofa
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