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anti-Roundabout, Axon Guidance Receptor, Homolog 4 (Drosophila) (ROBO4) Antibodies

Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. Additionally we are shipping ROBO4 Proteins (7) and ROBO4 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ROBO4 74144 Q8C310
ROBO4 54538 Q8WZ75
ROBO4 300518 Q80W87
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Top anti-ROBO4 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 2 to 3 Days
$304.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Mouse intestine cells probed with Rabbit Anti-Robo4 Polyclonal Antibody, FITC Conjugated (ABIN714866-FITC) (green) at 1:50 for 60 minutes compared to control cells (red). Rat brain lysate probed with Anti Robo4 Polyclonal Antibody, Unconjugated  at 1:3000 for 90 min at 37˚C. Predicted band 108kD. Observed band size: 171kD 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 16 Days
$218.90
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 5 to 6 Days
$506.80
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details

ROBO4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ROBO4 Antibodies

  1. Human Polyclonal ROBO4 Primary Antibody for ELISA - ABIN1999429 : Huminiecki, Gorn, Suchting, Poulsom, Bicknell: Magic roundabout is a new member of the roundabout receptor family that is endothelial specific and expressed at sites of active angiogenesis. in Genomics 2002 (PubMed)
    Show all 2 references for ABIN1999429

More Antibodies against ROBO4 Interaction Partners

Zebrafish Roundabout, Axon Guidance Receptor, Homolog 4 (Drosophila) (ROBO4) interaction partners

  1. Sox7 (show SOX7 Antibodies) and Sox18 (show SOX18 Antibodies)-mediated transcriptional regulation of Robo4 is important in the developing embryonic vasculature

  2. robo4 is essential for coordinated symmetric and directed sprouting of intersomitic vessels.

  3. Robo4 mediates attraction-signaling mechanisms through Rho GTPases in vertebrate vascular guidance

Mouse (Murine) Roundabout, Axon Guidance Receptor, Homolog 4 (Drosophila) (ROBO4) interaction partners

  1. Robo4 vaccines induce antibodies that retard tumor growth.

  2. Robo4 and Src family kinases are involved in the mechanisms of embryonic vascular defects caused by the Hrt/Hey deficiency.

  3. These results clearly indicate that Robo4 plays a role in hematopoietic stem cells trafficking such as bone marrow homing and peripheral mobilization.

  4. our results showed an important role of Robo4 in the regulation of cortical radial migration through Slit-dependent and -independent mechanisms

  5. Data found that expression of Slit2 (show SLIT2 Antibodies) and SDF1 (show CXCL12 Antibodies) were dynamically regulated in mesenchymal stem cells and OBC-like populations following radiation, while Robo4 expression was restricted to endothelial cells.

  6. augmenting the host Robo4/Slit2 system could provide a useful therapeutic approach to control pathological angiogenesis associated with HSV induced stromal keratitis

  7. Robo4 specifically binds to UNC5B (show UNC5B Antibodies), a vascular Netrin receptor, revealing unexpected interactions between two endothelial guidance receptors.

  8. Activating with the soluble ligand Slit an endothelium-specific, Robo4-dependent signaling pathway that strengthens the vascular barrier, diminishing deleterious aspects of the host's response to the pathogen-induced cytokine storm.

  9. enhanced growth of blood vessels in Robo4(-/-) endothelium is due to activation of vascular endothelial growth factor (VEGF)-R2 signaling through the Src and FAK kinases.

  10. Robo4 is a bona fide member of the Robo family and may provide a repulsive cue to migrating endothelial cells during vascular development.

Human Roundabout, Axon Guidance Receptor, Homolog 4 (Drosophila) (ROBO4) interaction partners

  1. there was a increase in Robo4 expression under hyperglycemic conditions, while there was a decrease under hypoxic and combined hypoxic and hyperglycemic conditions, suggesting Robo4 might play different roles in various stages of diabetic retinopathy

  2. These results suggest that Slit2 (show SLIT3 Antibodies)/Robo1 (show ROBO1 Antibodies) binding exerts an effect on cell migration, which is negatively regulated by Robo4, and Robo1 (show ROBO1 Antibodies) may function by interacting with CdGAP (show ARHGAP31 Antibodies) in HUVECs.

  3. results indicate that AP-1 (show FOSB Antibodies) complexes regulate Robo4 gene expression in endothelial cells

  4. BM Robo4 expression can serve as a new biomarker to predict clinical outcomes in AML (show RUNX1 Antibodies) patients and Robo4 may serve as a potential therapeutic target in patients with higher Robo4 expression.

  5. Robo4 suppressed glioma-induced endothelial cell proliferation, migration and tube formation in vitro by inhibiting VEGR2-mediated activation of PI3K (show PIK3CA Antibodies)/AKT (show AKT1 Antibodies) and FAK (show PTK2 Antibodies) signaling pathways.

  6. Increased or decreased expression of Robo4 by stimulation or knockdown of HIF-1alpha (show HIF1A Antibodies) suggesting that Robo4 is positively regulated by HIF-1alpha (show HIF1A Antibodies) under normoxic and hypoxic conditions in microvascular endothelial cells in vitro.

  7. Plasma Robo4 levels are increased, transiently, following cardiac surgery requiring CPB (show CPB1 Antibodies)

  8. This study demonistrated that roundabout (show ROBO1 Antibodies) 4 regulates blood-tumor barrier permeability through the modulation of ZO-1 (show TJP1 Antibodies), Occludin (show OCLN Antibodies), and Claudin-5 (show CLDN5 Antibodies) expression.

  9. Endothelial cell-specific DNA methylation (show HELLS Antibodies) pattern of the Robo4 proximal promoter is determined during cell differentiation and contributes to regulation of EC-specific Robo4 gene expression.

  10. SLIT3 (show SLIT1 Antibodies)-ROBO4 activation promotes vascular network formation in human engineered tissue and angiogenesis in vivo.

ROBO4 Antigen Profile

Protein Summary

Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins (By similarity).

Gene names and symbols associated with ROBO4

  • roundabout homolog 4 (robo4) antibody
  • roundabout homolog 4 (Drosophila) (Robo4) antibody
  • roundabout homolog 4, magic roundabout (Drosophila) (ROBO4) antibody
  • roundabout, axon guidance receptor, homolog 4 (Drosophila) (ROBO4) antibody
  • roundabout, axon guidance receptor, homolog 4 (Drosophila) (Robo4) antibody
  • 1200012D01Rik antibody
  • AI593217 antibody
  • ECSM4 antibody
  • MRB antibody
  • sc:d0823 antibody
  • wu:fa16f09 antibody

Protein level used designations for ROBO4

roundabout homolog 4 , magic roundabout , Magic roundabout , roundabout homolog 4, magic roundabout

GENE ID SPECIES
259253 Danio rerio
560765 Danio rerio
74144 Mus musculus
783785 Bos taurus
54538 Homo sapiens
489306 Canis lupus familiaris
100524821 Sus scrofa
300518 Rattus norvegicus
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