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anti-Runt-Related Transcription Factor 2 (RUNX2) Antibodies

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Additionally we are shipping RUNX2 Kits (49) and RUNX2 Proteins (12) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RUNX2 12393 Q08775
RUNX2 860 Q13950
RUNX2 367218  
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Top anti-RUNX2 Antibodies at antibodies-online.com

Showing 10 out of 201 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:2500Positive Control: HepG2 cell lysate Sample Type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Anti-rabbit-HRP Secondary Antibody Dilution: 1:00,000 Color/Signal Descriptions: RUNX2  Gene Name: Anonymous Submitted by: 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate WB Suggested Anti-RUNX2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate  RUNX2 is strongly supported by BioGPS gene expression data to be expressed in Human 721_B cells 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-RUNX2 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated DB Dot blot analysis of anti-Phospho-RUNX2-S533 Antibody (ABIN389942) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of anti-RUNX2 Antibody (S533) (ABIN392133) in HepG2 cell line lysates (35 µg/lane). RUNX2 (arrow) was detected using the purified polyclonal antibody. RUNX2 Antibody (S533) (ABIN392133) western blot analysis in Hob cell line lysates.This demonstrates the RUNX2 antibody detected the RUNX2 protein (arrow)(Kindly provided by Dr. John Wu). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Observed bind size: 62KD Anti-RUNX2 Picoband antibody,  All lanes: Anti RUNX2  at 0.5ug/ml WB: Recombinant Human RUNX2 Protein 0.5ng Predicted bind size: 50KD Observed bind size: 50KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-Runx2 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Rat Liver WB Suggested Anti-Runx2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Rat Liver 100 μL Log in to see 2 to 3 Days
$289.00
Details

RUNX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RUNX2 Antibodies

  1. Human Polyclonal RUNX2 Primary Antibody for DB - ABIN389942 : McNamara, Sjöström, Burgess, Kim, Liu, Gordonov, Moghe, Meek, Oreffo, Su, Dalby: Skeletal stem cell physiology on functionally distinct titania nanotopographies. in Biomaterials 2011 (PubMed)
    Show all 8 references for ABIN389942

  2. Human Polyclonal RUNX2 Primary Antibody for EIA - ABIN358487 : Ermakov, Malkin, Keter, Kobyliansky, Livshits: Family-based association study of polymorphisms in the RUNX2 locus with hand bone length and hand BMD. in Annals of human genetics 2008 (PubMed)
    Show all 3 references for ABIN358487

  3. Human Polyclonal RUNX2 Primary Antibody for WB - ABIN2780588 : Lee, Lee, Ryoo, Park, Park, Bae, Cho, Park: The odontogenic ameloblast-associated protein (ODAM) cooperates with RUNX2 and modulates enamel mineralization via regulation of MMP-20. in Journal of cellular biochemistry 2010 (PubMed)
    Show all 2 references for ABIN2780588

  4. Human Polyclonal RUNX2 Primary Antibody for EIA, WB - ABIN360019 : Rich, Rosová, Nolta, Myckatyn, Sandell, McAlinden: Upregulation of Runx2 and Osterix during in vitro chondrogenesis of human adipose-derived stromal cells. in Biochemical and biophysical research communications 2008 (PubMed)
    Show all 2 references for ABIN360019

  5. Cow (Bovine) Polyclonal RUNX2 Primary Antibody for WB - ABIN2774905 : Guo, Chung, Yang, Karsenty, Bringhurst, Kronenberg: PTH/PTHrP receptor delays chondrocyte hypertrophy via both Runx2-dependent and -independent pathways. in Developmental biology 2006 (PubMed)
    Show all 2 references for ABIN2774905

  6. Chicken Polyclonal RUNX2 Primary Antibody for WB - ABIN2774906 : Ducy, Zhang, Geoffroy, Ridall, Karsenty: Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. in Cell 1997 (PubMed)

More Antibodies against RUNX2 Interaction Partners

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. our studies reveal a novel function for Runx2 in regulating mammary epithelial cell regenerative potential, possibly acting as a downstream target of WNT (show WNT2 Antibodies) signalling.

  2. MED23 (show MED23 Antibodies) binds to RUNX2 and modulates its transcriptional activity.

  3. Hand1 (show HAND1 Antibodies) downregulated Ihh (show IHH Antibodies) gene expression in vitro by inhibiting Runx2 transactivation of the Ihh (show IHH Antibodies) proximal promoter.

  4. increased intranuclear actin forces MSC (show MSC Antibodies) into osteogenic lineage through controlling Runx2 activity; this process may be useful for clinical objectives of forming bone.

  5. We observed that tranilast increased mRNA expression of both Sox9 (show SOX9 Antibodies) and Runx2 in differentiating ATDC5 chondrogenic progenitor cells.

  6. Results propose that Utx (show KDM6A Antibodies) plays important roles in osteoblast differentiation by controlling the expressions of Runx2 and Osterix (show SP7 Antibodies).

  7. Somatic transmission of Runx2 mRNAs in osteoblasts and osteosarcoma cells represents a versatile mechanism for translational rather than transcriptional induction.

  8. The data indicate a critical role of Runx2 in Smooth muscle cell (SMC (show DYM Antibodies)) osteogenic phenotype change and mineral deposition in a mouse model of Arterial medial calcification (AMC).

  9. Gene expression of Tau, a neuronal phosphoprotein with important roles in neuronal biology and microtubule dynamics and assembly, was high in wild-type molars but severely reduced in transgenic(Col1a1 (show COL1A1 Antibodies)-Runx2) molars.

  10. Runx2/miR (show MLXIP Antibodies)-3960/miR (show MLXIP Antibodies)-2861 positive feedback loop plays an important role in osteogenic transdifferentiation of vascular smooth muscle cells and contributes to vascular calcification.

Human Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. GnRH (show GNRH1 Antibodies) regulates trophoblast invasion via RUNX2-mediated MMP2 (show MMP2 Antibodies)/MMP9 (show MMP9 Antibodies) expression.

  2. An osteogenic medium is required for the differentiation of adul tmesenchymal stem cells, which is also under RUNX2 regulation. These findings are potentially valuable for clinical practice.

  3. This integrative genomic study confirmed the role of RUNX2 as a potential driver of AS and identified a new AS susceptibility gene, CACNA1C (show CACNA1C Antibodies), belonging to the calcium signaling pathway.

  4. It is suggested that oxytalan-positive POFs, purportedly originating from the periodontal ligament, express molecules that are specific to bone and cementum (Runx-2, BMP-2 (show BMP2 Antibodies)), or cementum only (CAP).

  5. results reveal the regulatory circuit between RUNX2 and SMURF1 (show SMURF1 Antibodies) controls RUNX2 expression and regulates odntoblastic differentiation in hDPSCs.

  6. Data suggest that RUNX2 transcription factor:TAZ transcriptional co-activator and activation of sE-Cadherin/proto-oncogene (show RAB1A Antibodies) protein HER-2 (show ERBB2 Antibodies) signaling could be potential oncogenic pathways for breast cancer (BC) metastasis.

  7. RUNX2 mediates epigenetic regulation of the survival of p53 (show TP53 Antibodies) defective osteosarcoma cells.

  8. Studies indicate the involvement of estrogen signaling in breast cancer development and the interaction between RUNX2 and estrogen-dependent pathways can contribute to the mechanisms involved in cancer transformation. [review]

  9. that STAT-5 (show STAT5A Antibodies), RUNX-2, and FGFR-2 (show FGFR2 Antibodies) may have a role in the progression of the mucinous phenotype, in which nuclear STAT-5 (show STAT5A Antibodies) may inhibit RUNX-2 prometastatic effect

  10. Our findings suggest that suppression of miR (show MLXIP Antibodies)-222-3p activity promoted osteogenic differentiation hBMSCs through regulating Smad5 (show SMAD5 Antibodies)-RUNX2 signaling axis.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data also indicate that MGP (show MGP Antibodies) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

RUNX2 Antigen Profile

Protein Summary

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Gene names and symbols associated with RUNX2

  • runt-related transcription factor 2a (runx2a) antibody
  • transcription factor Cbfa1 (runx2) antibody
  • runt-related transcription factor 2 (RUNX2) antibody
  • runt-related transcription factor 2 (runx2) antibody
  • runt related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (LOC100339156) antibody
  • runt-related transcription factor 2-like (LOC100737965) antibody
  • AML3 antibody
  • Cbf antibody
  • CBF-alpha-1 antibody
  • Cbfa-1 antibody
  • CBFA1 antibody
  • CCD antibody
  • CCD1 antibody
  • CLCD antibody
  • LS3 antibody
  • OSF-2 antibody
  • OSF2 antibody
  • PEA2aA antibody
  • Pebp2a1 antibody
  • pebp2a2 antibody
  • PEBP2aA antibody
  • pebp2aa1 antibody
  • Pebpa2a antibody
  • RUNX2 antibody

Protein level used designations for RUNX2

runt-related transcription factor 2 , transcription factor Runx2a , transcription factor Cbfa1 , runt-related transcription factor 2-like , AKV core binding factor , CBF-alpha-1 , PEA2-alpha A , PEBP2 alpha A , SL3-3 enhancer factor 1 alpha A subunit , acute myeloid leukemia 3 protein , core binding factor alpha 1 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt domain, alpha subunit 1 , PEBP2-alpha A , SL3/AKV core-binding factor alpha A subunit , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , runt-related factor 2 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II , core binding factor alpha 1 subunit

GENE ID SPECIES
405784 Danio rerio
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
12393 Mus musculus
860 Homo sapiens
474923 Canis lupus familiaris
536911 Bos taurus
100008943 Oryctolagus cuniculus
367218 Rattus norvegicus
100037059 Xenopus laevis
373919 Gallus gallus
100734175 Cavia porcellus
100033890 Equus caballus
100155806 Sus scrofa
100339156 Oryctolagus cuniculus
100861217 Capra hircus
101115489 Ovis aries
100737965 Sus scrofa
Selected quality suppliers for anti-RUNX2 (RUNX2) Antibodies
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