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anti-Runt-Related Transcription Factor 3 (RUNX3) Antibodies

RUNX3 encodes a member of the runt domain-containing family of transcription factors. Additionally we are shipping RUNX3 Proteins (13) and RUNX3 Kits (2) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
RUNX3 12399  
RUNX3 864 Q13761
RUNX3 156726  
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Top anti-RUNX3 Antibodies at antibodies-online.com

Showing 10 out of 187 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-RUNX3 Antibody Titration: 1.25ug/mlELISA Titer: 1:12500Positive Control: NIH/3T3 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in HL-60 cell line lysates (35 ug/lane) using RUNX3 Antibody (Center) Cat.-No. AP53770PU-N. This demonstrates the RUNX3 antibody detected the RUNX3 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ICC, FACS, IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Allophycocyanin FACS Detection of RUNX3/CBFA3 in Human PBMC lymphocytes by Flow Cytometry. Human peripheral blood mononuclear cells (PBMC) lymphocytes either (A) untreated or (B) treated with PMA were stained with Mouse Anti-Human RUNX3/CBFA3 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$439.69
Details
Human Mouse Un-conjugated FACS, ICC, SimWes, WB Detection of Human RUNX3/CBFA3 by Simple WesternTM. Simple Western lane view shows lysates of Jurkat human acute T cell leukemia cell line and Daudi human Burkitt's lymphoma cell line, loaded at 0.5 mg/mL. A specific band was detected for RUNX3/CBFA3 at approximately 54 kDa (as indicated) using 10 ug/mL of Mouse Anti-Human/Mouse RUNX3/CBFA3 Monoclonal Antibody. This experiment was conducted under reducing conditions and using the 12-230 kDa separation system. Detection of RUNX3/CBFA3 in Human PBMC by Flow Cytometry. Human PBMC unstimulated (light orange filled histogram) or treated with 50ng/mL PMA (dark orange filled histogram) were stained with Mouse Anti-Human/Mouse RUNX3/CBFA3 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 6 to 7 Days
$333.38
Details
Human Rabbit Un-conjugated IF, IHC (p), WB RUNX3 Antibody (Center) (ABIN658684) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the RUNX3 antibody detected the RUNX3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 14 Days
$175.80
Details
Mouse Rabbit Un-conjugated WB Anti- RUNX3 antibody, Western blotting All lanes: Anti RUNX3  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Mouse Liver Tissue Lysate at 50ug Predicted bind size: 44KD Observed bind size: 44KD 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- RUNX3 Picoband antibody, IHC(P) IHC(P): Rat Spleen Tissue Anti- RUNX3 Picoband antibody, IHC(P) IHC(P): Human Intestinal Cancer Tissue 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated ELISA, WB RUNX3 polyclonal antibody (A01), Lot # 070226JCSa Western Blot analysis of RUNX3 expression in HepG2 . Western Blot detection against Immunogen (35.57 KDa) . 50 μL Log in to see 9 Days
$298.57
Details

RUNX3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-RUNX3 Antibodies

  1. Human Polyclonal RUNX3 Primary Antibody for EIA, WB - ABIN954644 : Tsang, Lamb, Romero-Gallo, Huang, Ito, Peek, Ito, Chen: Helicobacter pylori CagA targets gastric tumor suppressor RUNX3 for proteasome-mediated degradation. in Oncogene 2010 (PubMed)
    Show all 5 references for ABIN954644

  2. Human Polyclonal RUNX3 Primary Antibody for ELISA, WB - ABIN560191 : Nakamura, Senzaki, Yoshikawa, Nishimura, Inoue, Ito, Ozaki, Shiga: Dynamic regulation of the expression of neurotrophin receptors by Runx3. in Development (Cambridge, England) 2008 (PubMed)
    Show all 5 references for ABIN560191

  3. Human Monoclonal RUNX3 Primary Antibody for FACS, ICC - ABIN4899364 : Chopin, Seillet, Chevrier, Wu, Wang, Morse, Belz, Nutt: Langerhans cells are generated by two distinct PU.1-dependent transcriptional networks. in The Journal of experimental medicine 2013 (PubMed)
    Show all 2 references for ABIN4899364

  4. Human Monoclonal RUNX3 Primary Antibody for ICC, FACS - ABIN1724742 : Mei, Bai, Liu, Li, Wu, Yu, Zheng: RUNX3 expression is lost in glioma and its restoration causes drastic suppression of tumor invasion and migration. in Journal of cancer research and clinical oncology 2011 (PubMed)

  5. Human Polyclonal RUNX3 Primary Antibody for IF, IHC (p) - ABIN658684 : Zhu, Xu, Hu, Feng, Jiang, Hou, Cao, Han, Ling, Ge: Pim-1 acts as an oncogene in human salivary gland adenoid cystic carcinoma. in Journal of experimental & clinical cancer research : CR 2015 (PubMed)

  6. Cow (Bovine) Polyclonal RUNX3 Primary Antibody for WB - ABIN2780022 : Yarmus, Woolf, Bernstein, Fainaru, Negreanu, Levanon, Groner: Groucho/transducin-like Enhancer-of-split (TLE)-dependent and -independent transcriptional regulation by Runx3. in Proceedings of the National Academy of Sciences of the United States of America 2006 (PubMed)

More Antibodies against RUNX3 Interaction Partners

Zebrafish Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. successive induction of the transcription factors Runx3, Egr1 and Sox9b constitutes a regulatory cascade that controls expression of Follistatin A in pharyngeal endoderm, the latter modulating BMP signaling in developing cranial cartilage in zebrafish

  2. Runx3 expression leads to an increase in primitive blood cell numbers, together with an increase in runx1 (show RUNX1 Antibodies)-expressing cells in the ventral wall of the dorsal aorta.

  3. Zebrafish embryos lacking Rad21 (show RAD21 Antibodies), or cohesin subunit Smc3 (show SMC3 Antibodies), fail to express runx3 and lose hematopoietic runx1 (show RUNX1 Antibodies) expression in early embryonic development.

Mouse (Murine) Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. our data suggest that Runx3 may play a crucial role in the development of DRGs by regulating the expression of Ntrk3 (show NTRK3 Antibodies) variants

  2. Runx3 is crucial for the phenotypic and functional changes observed in ThPok (show ZBTB7B Antibodies)-deficient invariant natural killer T cells.

  3. the transcription factor Runx3 was essential for the normal development of subsets of innate lymphoid cells (ILCs) in the mucosa

  4. Runx1 and Runx3 are the downstream effectors of Nanog, especially in the early and intermediate osteogenic differentiation of the mouse mesenchymal cell line C3H10T1/2.

  5. nonpermissive expression of RUNX3 protein is restricted at the translational level, and that the repression is further enforced by a transcriptional regulation for maintenance of diverse developmental plasticity of T cells for different effector subsets.

  6. Our findings establish Nr4a1 (show NR4A1 Antibodies) as a novel and critical player in the regulation of CD8 (show CD8A Antibodies) T cell development through the direct suppression of Runx3.

  7. Runx1 (show RUNX1 Antibodies) Runx3 DKO mice exhibit bone marrow failure and myeloproliferative disorder. RUNX proteins are important for FANCD2 (show FANCD2 Antibodies) recruitment to DNA repair foci.

  8. inflammation-mediated tumor promotion requires leukocytic Runx3 expression

  9. Bone histomorphometry revealed that decreased osteoblast numbers and reduced mineral deposition capacity in Runx3-deficient mice cause this bone formation deficiency.

  10. RUNX3 expression suppresses metastasis and angiogenesis of human prostate cancer.

Human Runt-Related Transcription Factor 3 (RUNX3) interaction partners

  1. RUNX3 promoter methylation is linked to the origin of HCC (show FAM126A Antibodies) but not to its progression from non-metastatic to metastatic stages.

  2. hypermethylation modifications of CpG13, CpG14, and CpG15 (show NRN1 Antibodies) in the promoter region of Runx3 could result in the down regulation of Runx3 expression to affect the prognosis of Chronic Atrophic Gastritis Patients. So the methylation levels of these CpG sites in Runx3 in the peripheral blood can be used as the biomarker for predicting the healing prognosis of Chronic Atrophic Gastritis Patients patients.

  3. miR (show MLXIP Antibodies)-148a-3p may regulate RUNX3 expression through the modulation of DNMT1 (show DNMT1 Antibodies)-dependent DNA methylation (show HELLS Antibodies) in laryngeal squamous cell carcinoma.

  4. miR (show MLXIP Antibodies)-130b expression was downregulated, while RUNX3 mRNA was upregulated, in EOC tissues compared to normal ovarian tissues (both P=0.001). Importantly, the expression level of miR (show MLXIP Antibodies)-130b in EOC tissues was negatively correlated with that of RUNX3 mRNA significantly.

  5. N-myc protein (show MYCN Antibodies) also could bind to the promoter of pri-miR (show MLXIP Antibodies)-4295 and inhibit the expression of RUNX3 in glioma cells.

  6. miR (show MLXIP Antibodies)-532-5p functions as an oncogenic miRNA by promoting cell growth, migration and invasion in human gastric cancer cells via regulation of RUNX3 gene expression.

  7. loss of RUNX3 expression contributed to 5-FU and CDDP resistance by inducing multidrug resistance proteins expression.

  8. Results show up-regulation of TrkB (show NTRK2 Antibodies) and down-regulation of Runx3 and Keap1 (show KEAP1 Antibodies) in breast cancer cells and suggest that TrkB (show NTRK2 Antibodies) plays a key role in tumorigenicity and metastasis of breast cancer cells through suppression of Runx3 or Keap1 (show KEAP1 Antibodies).

  9. In the present review, we summarize the proposed roles of RUNX3 in metastasis and, when applicable, highlight the mechanism by which they function.

  10. the AA genotype and A allele of rs2236852 polymorphism confer a decreased CRC (show CALR Antibodies) risk, while the TA haplotype (rs760805 and rs2236852) increases the risk for CRC (show CALR Antibodies) development in Mexican patients.

RUNX3 Antigen Profile

Protein Summary

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with RUNX3

  • runt-related transcription factor 3 (runx3) antibody
  • runt-related transcription factor 3 (RUNX3) antibody
  • frRunx3/p45 (frrunx3) antibody
  • runt related transcription factor 3 (Runx3) antibody
  • runt-related transcription factor 3 (Runx3) antibody
  • AML2 antibody
  • Cbfa3 antibody
  • frrunx3 antibody
  • Pebp2a3 antibody
  • PEBP2aC antibody
  • runx3 antibody
  • runxb antibody

Protein level used designations for RUNX3

runt-related transcription factor b , runt-related transcription factor 3 , core-binding factor 3 , frRunx3/p45 , CBF-alpha-3 , PEA2-alpha C , PEBP2-alpha C , SL3-3 enhancer factor 1 alpha C subunit , SL3/AKV core-binding factor alpha C subunit , acute myeloid leukemia 2 protein , core binding factor alpha 3 , core-binding factor subunit alpha-3 , oncogene AML-2 , polyomavirus enhancer-binding protein 2 alpha C subunit , runt domain, alpha subunit 3 , transcription factor AML2/CBFA3 , PEA2 alpha C , PEBP2 alpha C , acute myeloid leukemia gene 2 , core-binding factor, runt domain, alpha subunit 3 , transcription factor AML2 , Runt related transcription factor 3 , Runx3 MASN-variant

GENE ID SPECIES
58127 Danio rerio
403159 Sus scrofa
456633 Pan troglodytes
100049632 Takifugu rubripes
100474431 Ailuropoda melanoleuca
100500732 Xenopus laevis
12399 Mus musculus
864 Homo sapiens
617389 Bos taurus
156726 Rattus norvegicus
769687 Gallus gallus
487366 Canis lupus familiaris
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