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Runt-Related Transcription Factor 2 (RUNX2) ELISA Kits

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Additionally we are shipping RUNX2 Antibodies (235) and RUNX2 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RUNX2 12393 Q08775
RUNX2 860 Q13950
RUNX2 367218  
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Top RUNX2 ELISA Kits at antibodies-online.com

Showing 10 out of 46 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Mouse 0.116 ng/mL 0.31-20 ng/mL Typical Standard Curve for Mouse RUNX2 ELISA. 96 Tests Log in to see 13 to 16 Days
$576.00
Details
Rat 0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 1.875 ng/mL 3.125-200 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Sheep
  96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced RUNX2 ELISA Kits

  1. Human RUNX2 ELISA Kit for Sandwich ELISA - ABIN416824 : Nagy, Eriksson, Yousry, Caidahl, Ingelsson, Hansson, Franco-Cereceda, Bäck: Valvular osteoclasts in calcification and aortic valve stenosis severity. in International journal of cardiology 2013 (PubMed)
    Show all 2 references for ABIN416824

More ELISA Kits for RUNX2 Interaction Partners

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Klotho (show KL ELISA Kits) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (show GRK4 ELISA Kits)-RUNX2 pathway.

  2. Runx2 might act downstream of C/EBPbeta (show CEBPB ELISA Kits) to regulate the expression of Cox-2 (show COX2 ELISA Kits), Vegf (show VEGFA ELISA Kits) and Mmp9 (show MMP9 ELISA Kits) in the uterine stromal cells.

  3. PP5 (show PPP5C ELISA Kits) is a unique phosphatase reciprocally regulating PPARgamma (show PPARG ELISA Kits) and RUNX2 activities in marrow mesenchymal stem cell

  4. results reveal a central mechanism underlying lineage-specific regulation by a Runx2/DICER (show DICER1 ELISA Kits)/miRNAs cascade during osteogenic differentiation and bone development

  5. Perlecan (show HSPG2 ELISA Kits) is required for the chondrogenic and adipogenic differentiation from SMCs via its regulation of the Sox9 (show SOX9 ELISA Kits) and PPARgamma (show PPARG ELISA Kits) gene expression, but not for osteogenic differentiation via Runx2

  6. results indicate that the activity of the canonical Wnt (show WNT2 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway in osteoblast is modulated by Runx2fa

  7. in murine bone marrow stromal cells undergoing osteogenic differentiation, TNF-alpha (show TNF ELISA Kits) and it activated NF-kappaB (show NFKB1 ELISA Kits) pathway inhibit the expression of Runx2 gene, and suppress the Runx2-mediated osteogenic gene transcription via the 9.0 kb BSP (show KLK6 ELISA Kits) promoter.

  8. results suggest that 1,25(OH)D induces the transdifferentiation of osteoblasts to adipocytes via Runx2 downregulation in osteoblasts.

  9. In a model of instability-induced osteoarthritis, Runx2 was overexpressed in articular chondrocytes and osteophyte-forming cells in LOX-1 (show OLR1 ELISA Kits)(+)/(+) mice and was significantly downregulated in articular chondrocytes and osteophyte-forming cells in LOX-1 (show OLR1 ELISA Kits)(-)/(-) mice.

  10. miR23b inhibits BMP9induced C2C12 myoblast osteogenesis via targeting of the Runx2 gene, acting as a suppressor.

Human Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. deregulation of miR (show MLXIP ELISA Kits)-320a/RUNX2/CYP11A1 (show CYP11A1 ELISA Kits) (CYP19A1 (show CYP19A1 ELISA Kits)) cascade plays an important role in the development of estrogen deficiency in human cumulus granulosa cells

  2. These results indicate that VEGF-C (show VEGFC ELISA Kits)-induced MSC (show MSC ELISA Kits) osteogenesis is mediated through VEGFR2 (show KDR ELISA Kits) and VEGFR3 (show FLT4 ELISA Kits), and followed the activation of the ERK (show EPHB2 ELISA Kits)/RUNX2 signaling pathway.

  3. TRbeta (show TXNRD2 ELISA Kits) suppressed Runx2 transcriptional activities, thus confirming TRbeta (show TXNRD2 ELISA Kits) regulation of Runx2 at functional thyroid hormone (show PTH ELISA Kits)-response elements. Significantly, these findings indicate that a ratio of the tumor-suppressor TRbeta (show TXNRD2 ELISA Kits) and tumor-promoting Runx2 may reflect tumor aggression and serve as biomarkers in biopsy tissues. The discovery of this TRbeta (show TXNRD2 ELISA Kits)-Runx2 signaling supports the emerging role of TRbeta (show TXNRD2 ELISA Kits) as a tumor supp...

  4. Sm51 plays an important role in regulating osteogenic differentiation of mesenchymal stem cells through increasing Runx2 expression

  5. One association in the CTNNA2 (show CTNNA2 ELISA Kits) gene on chromosome 2p12 [rs1567532, hazard ratio (HR) = 1.75, 95% confidence interval (CI) 1.19-2.58, P = 0.005 for homozygotes for the minor allele] and one in the last intron of the RUNX2 gene on chromosome 6p21 (rs12209785, HR = 0.88, 95% CI 0.80-0.98, P = 0.014 for heterozygotes) are of particular relevance. These loci do not coincide with those that showed the strongest associations in t

  6. miR (show MLXIP ELISA Kits)-590-5p promotes osteoblast differentiation by indirectly protecting and stabilizing the Runx2 protein by targeting Smad7 (show SMAD7 ELISA Kits) gene expression.

  7. The results indicate that Runx2 could promote EMT (show ITK ELISA Kits) and VM formation in HCC (show FAM126A ELISA Kits) and Galectin-3 (show LGALS3 ELISA Kits) might have some function in this process.

  8. the findings of the present study provided novel insights into the control of IPO8 (show IPO8 ELISA Kits) transcription, and may enhance understanding regarding RUNX2 regulatory mechanisms in osteoblast differentiation, bone development, and degenerative bone disease.

  9. Findings suggest thatSirt1 may regulate the expression of Runx2, which is the osteogenic transcription factor, and the production of MMP-13 (show MMP13 ELISA Kits) from chondrocytes in OA.

  10. Runx2 is a direct downstream target of miR (show MLXIP ELISA Kits)-455 in hepatocellular carcinoma.

Rabbit Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  2. The OPG (show TNFSF11 ELISA Kits) expression levels decreased while those of RANKL (show TNFSF11 ELISA Kits) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data also indicate that MGP (show MGP ELISA Kits) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

Pig (Porcine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Klotho (show KL ELISA Kits) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (show GRK4 ELISA Kits)-RUNX2 pathway.

RUNX2 Antigen Profile

Antigen Summary

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Gene names and symbols associated with RUNX2

  • runt-related transcription factor 2a (runx2a) antibody
  • transcription factor Cbfa1 (runx2) antibody
  • runt-related transcription factor 2 (RUNX2) antibody
  • runt-related transcription factor 2 (runx2) antibody
  • runt related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (LOC100339156) antibody
  • runt-related transcription factor 2-like (LOC100737965) antibody
  • AML3 antibody
  • Cbf antibody
  • CBF-alpha-1 antibody
  • Cbfa-1 antibody
  • CBFA1 antibody
  • CCD antibody
  • CCD1 antibody
  • CLCD antibody
  • LS3 antibody
  • OSF-2 antibody
  • OSF2 antibody
  • PEA2aA antibody
  • Pebp2a1 antibody
  • pebp2a2 antibody
  • PEBP2aA antibody
  • pebp2aa1 antibody
  • Pebpa2a antibody
  • RUNX2 antibody

Protein level used designations for RUNX2

runt-related transcription factor 2 , transcription factor Runx2a , transcription factor Cbfa1 , runt-related transcription factor 2-like , AKV core binding factor , CBF-alpha-1 , PEA2-alpha A , PEBP2 alpha A , SL3-3 enhancer factor 1 alpha A subunit , acute myeloid leukemia 3 protein , core binding factor alpha 1 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt domain, alpha subunit 1 , PEBP2-alpha A , SL3/AKV core-binding factor alpha A subunit , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , runt-related factor 2 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II , core binding factor alpha 1 subunit

GENE ID SPECIES
405784 Danio rerio
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
12393 Mus musculus
860 Homo sapiens
474923 Canis lupus familiaris
536911 Bos taurus
100008943 Oryctolagus cuniculus
367218 Rattus norvegicus
100037059 Xenopus laevis
373919 Gallus gallus
100734175 Cavia porcellus
100033890 Equus caballus
100155806 Sus scrofa
100339156 Oryctolagus cuniculus
100861217 Capra hircus
101115489 Ovis aries
100737965 Sus scrofa
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