Runt-Related Transcription Factor 2 (RUNX2) ELISA Kits

RUNX2 is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. Additionally we are shipping RUNX2 Antibodies (237) and RUNX2 Proteins (12) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RUNX2 12393 Q08775
RUNX2 860 Q13950
RUNX2 367218  
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Top RUNX2 ELISA Kits at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 13 to 16 Days
$560.00
Details
Mouse 0.117 ng/mL 0.312-20 ng/mL 96 Tests Log in to see 15 to 17 Days
$891.06
Details
Rat 0.78 ng/mL 3.12-200 ng/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Human 0.056 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 2 to 3 Days
$779.90
Details
Guinea Pig 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Rabbit 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details
Pig 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Chicken 1.875 ng/mL 3.125-200 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Monkey 0.188 ng/mL 0.313-20 ng/mL   96 Tests Log in to see 12 to 14 Days
$715.00
Details
Dog 0.1 ng/mL 1.0-25 ng/mL   96 Tests Log in to see 15 to 18 Days
$707.14
Details

Top referenced RUNX2 ELISA Kits

  1. Human RUNX2 ELISA Kit for Sandwich ELISA - ABIN416824 : Nagy, Eriksson, Yousry, Caidahl, Ingelsson, Hansson, Franco-Cereceda, Bäck: Valvular osteoclasts in calcification and aortic valve stenosis severity. in International journal of cardiology 2013 (PubMed)
    Show all 2 Pubmed References

More ELISA Kits for RUNX2 Interaction Partners

Zebrafish Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Runx2 may have an evolutionarily conserved role in axis formation

Mouse (Murine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. SIRT1 (show SIRT1 ELISA Kits) interacts with and promotes the transactivation potential of RUNX2.

  2. ABL (show ABL1 ELISA Kits) potentiated the assembly and activation of the RUNX2-TAZ (show TAZ ELISA Kits) master transcription factor complex that is required for osteoblastogenesis, while antagonizing PPARgamma (show PPARG ELISA Kits)-mediated adipogenesis.

  3. urther investigation indicated that p205 (show GNB2L1 ELISA Kits) may disturb the formation of Runx2/Ids (show IDS ELISA Kits) complex and free more Runx2 to induce the differentiation process. Taken together, our findings demonstrated for the first time that p205 (show GNB2L1 ELISA Kits) functions as an activator in osteoblast differentiation.

  4. identified a novel genomic region in which DNA methylation (show HELLS ELISA Kits) status is related to Runx2 expression and detected demethylation of Runx2-DMR (show WDR20 ELISA Kits) during osteoblastic differentiation in mouse and dog.

  5. overexpression of Fam3c (show FAM3C ELISA Kits) caused reduction of Runx2 expression at both mRNA and protein levels. Fam3c (show FAM3C ELISA Kits) was localized in the cytoplasm and it was not secreted outside the cell during osteoblast differentiation and therefore, may function intracellularly. Furthermore, Fam3c (show FAM3C ELISA Kits) and TGF-beta1 (show TGFB1 ELISA Kits) were found to regulate each other reciprocally

  6. MAP kinase (show MAPK1 ELISA Kits)-dependent RUNX2 phosphorylation Is necessary for epigenetic modification of chromatin during osteoblast differentiation.

  7. These results suggested that endogenous PTH enhanced BMPR2 expression by a cAMP/PKA/CREB pathway in osteoblasts, and increased RUNX2 expression through transduction of the BMP/pSMAD1/5/8 signaling pathway

  8. suggest that RUNX2 and USAG-1 (show SOSTDC1 ELISA Kits) act in an antagonistic manner

  9. results provide evidence that WWP2 (show WWP2 ELISA Kits) serves as a positive regulator of osteogenesis by augmenting RUNX2 transactivation in a non-proteolytic mono-ubiquitination manner.

  10. Klotho (show KL ELISA Kits) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (show GRK4 ELISA Kits)-RUNX2 pathway.

Human Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Mutation in the RUNX2 gene is associated with acute myeloid leukemia (show BCL11A ELISA Kits) patients with lympho-myeloid clonal hematopoiesis.

  2. present observations strongly suggest that RUNX2/mutant p53 (show TP53 ELISA Kits)/TAp63-regulatory axis is one of the key determinants of SAHA sensitivity of p53 (show TP53 ELISA Kits)-mutated pancreatic cancer cells

  3. All the three novel RUNX2 mutations significantly reduced the transactivation activity of RUNX2 on osteocalcin (show BGLAP ELISA Kits) promoter.

  4. miR (show MLXIP ELISA Kits)-466-mediated attenuation of RUNX2 as a novel therapeutic approach to regulate prostate cancer growth, particularly metastasis to bone.

  5. miR (show MLXIP ELISA Kits)-203 has a crucial role in suppressing heterotopic ossification by directly targeting Runx2.

  6. mechanical load upregulates expression of Runx2 gene via potentiation of PC1 (show PCSK1 ELISA Kits)-JAK2 (show JAK2 ELISA Kits)/STAT3 (show STAT3 ELISA Kits) signaling axis, culminating to possibly control osteoblastic differentiation and ultimately bone formation.

  7. the Runx2 knockdown cells displayed activation of AMP-activated protein kinase (AMPKalpha (show GRK4 ELISA Kits)), the sensor of cellular metabolism. Importantly, the Runx2 knockdown in bone-derived cells resulted in increased sensitivity to both Erk1/2 (show MAPK1/3 ELISA Kits) inhibition and AMPKalpha (show GRK4 ELISA Kits) activation by PD184161 and metformin, respectively, despite increased IGF-1Rbeta and AMPKalpha (show GRK4 ELISA Kits) levels.

  8. RUNX2 mutation disturbs the modulatory effects of dental follicle cells and periodontal ligament cells on the differentiation of osteoclasts and osteoblasts, thereby interfering with bone remodelling. These effects may contribute in part to the pathological manifestations of retention of primary teeth and delayed eruption of permanent teeth in patients with cleidocranial dysplasia.

  9. RUNX2/P57 (show CDKN1C ELISA Kits) gene expression is strongly activated, in a process that is accompanied by enrichment of activating histone marks (H3K4me3, H3ac, and H3K27ac) at the P1 promoter region, to control osteogenic lineage commitment of umbilical cord derived mesenchymal stem cells.

  10. provide evidence to show that CBX4 may serve as a tumor suppressor in colorectal carcinoma by recruiting HDAC3 (show HDAC3 ELISA Kits) to the Runx2 promoter to impede Runx2 expression

Rabbit Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. The results suggest that gene therapy using Runx2-modi fi ed dental pulp stem cells was more effective during bone deposition and new bone formation in tibia Distraction osteogenesis.

  2. Runx2-modified adipose-derived stem cells promote tendon graft integration in anterior cruciate ligament reconstruction.

  3. The OPG (show TNFSF11 ELISA Kits) expression levels decreased while those of RANKL (show TNFSF11 ELISA Kits) and RUNX2 increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

Xenopus laevis Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. These data also indicate that MGP (show MGP ELISA Kits) is under dual regulation by runx2 through the use of various isoforms and context-dependent formation of transcriptional complexes.

Pig (Porcine) Runt-Related Transcription Factor 2 (RUNX2) interaction partners

  1. Klotho (show KL ELISA Kits) gene deficiency promotes high-fat diet-induced fibrosis in aortic valves, likely through the AMPKalpha (show GRK4 ELISA Kits)-RUNX2 pathway.

RUNX2 Antigen Profile

Antigen Summary

This gene is a member of the RUNX family of transcription factors and encodes a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. The protein can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in this gene have been associated with the bone development disorder cleidocranial dysplasia (CCD). Transcript variants that encode different protein isoforms result from the use of alternate promoters as well as alternate splicing.

Gene names and symbols associated with RUNX2

  • runt-related transcription factor 2a (runx2a) antibody
  • transcription factor Cbfa1 (runx2) antibody
  • runt-related transcription factor 2 (RUNX2) antibody
  • runt-related transcription factor 2 (runx2) antibody
  • runt related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (Runx2) antibody
  • runt-related transcription factor 2 (LOC100339156) antibody
  • runt-related transcription factor 2-like (LOC100737965) antibody
  • AML3 antibody
  • Cbf antibody
  • CBF-alpha-1 antibody
  • Cbfa-1 antibody
  • CBFA1 antibody
  • CCD antibody
  • CCD1 antibody
  • CLCD antibody
  • LS3 antibody
  • OSF-2 antibody
  • OSF2 antibody
  • PEA2aA antibody
  • Pebp2a1 antibody
  • pebp2a2 antibody
  • PEBP2aA antibody
  • pebp2aa1 antibody
  • Pebpa2a antibody
  • RUNX2 antibody

Protein level used designations for RUNX2

runt-related transcription factor 2 , transcription factor Runx2a , transcription factor Cbfa1 , runt-related transcription factor 2-like , AKV core binding factor , CBF-alpha-1 , PEA2-alpha A , PEBP2 alpha A , SL3-3 enhancer factor 1 alpha A subunit , acute myeloid leukemia 3 protein , core binding factor alpha 1 , osteoblast-specific transcription factor 2 , polyomavirus enhancer-binding protein 2 alpha A subunit , runt domain, alpha subunit 1 , PEBP2-alpha A , SL3/AKV core-binding factor alpha A subunit , core-binding factor, runt domain, alpha subunit 1 , oncogene AML-3 , runt-related factor 2 , core-binding factor subunit alpha-1 , runt related transcription factor 2 , Runx2 spliced isoform , runt-related transcription factor 2 type I , runt-related transcription factor 2 type II , core binding factor alpha 1 subunit

GENE ID SPECIES
405784 Danio rerio
445986 Takifugu rubripes
449531 Canis lupus familiaris
472017 Pan troglodytes
703331 Macaca mulatta
100080409 Ornithorhynchus anatinus
100189546 Xenopus (Silurana) tropicalis
100222668 Taeniopygia guttata
100406564 Callithrix jacchus
100453201 Pongo abelii
100549663 Meleagris gallopavo
100555776 Anolis carolinensis
100619969 Monodelphis domestica
12393 Mus musculus
860 Homo sapiens
474923 Canis lupus familiaris
536911 Bos taurus
100008943 Oryctolagus cuniculus
367218 Rattus norvegicus
100037059 Xenopus laevis
373919 Gallus gallus
100734175 Cavia porcellus
100033890 Equus caballus
100155806 Sus scrofa
100339156 Oryctolagus cuniculus
100861217 Capra hircus
101115489 Ovis aries
100737965 Sus scrofa
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