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Ryanodine Receptor 2 (Cardiac) (RYR2) ELISA Kits

RYR2 encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. Additionally we are shipping RYR2 Antibodies (32) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
RYR2 6262 Q92736
Anti-Rat RYR2 RYR2 689560 B0LPN4
Anti-Mouse RYR2 RYR2 20191 E9Q401
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Top RYR2 ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.107 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details

More ELISA Kits for RYR2 Interaction Partners

Rabbit Ryanodine Receptor 2 (Cardiac) (RYR2) interaction partners

  1. Two regions of the ryanodine receptor (show RYR3 ELISA Kits) calcium channel are involved in Ca(2 (show CA2 ELISA Kits)+)-dependent inactivation

  2. [REVIEW] The efficacy of divalent calcium ion (Ca2 (show CA2 ELISA Kits)+) release in the myocardium depends on the amount of Ca2 (show CA2 ELISA Kits)+ loaded into the Ca2 (show CA2 ELISA Kits)+ store and the way in which this Ca2 (show CA2 ELISA Kits)* load influences the activity of the ryanodine receptor (show RYR3 ELISA Kits) Ca2+ release channel (RyR2).

  3. There were substantial transmural gradients in Cav1.2 (show CACNA1C ELISA Kits), KChIP2 (show KCNIP2 ELISA Kits), ERG (show KCNH2 ELISA Kits), KvLQT1 (show KCNQ1 ELISA Kits), Kir2.1 (show KCNJ2 ELISA Kits), NCX1 (show SLC8A1 ELISA Kits), SERCA2a (show ATP2A2 ELISA Kits) and RyR2 at the mRNA and, in some cases, protein level-in every case the mRNA or protein was more abundant in the epicardium than the endocardium.

  4. phosphorylation and K201 acted similarly to change the conformation of RyR1/2 and regulate FKBP12/12.6 binding.

Human Ryanodine Receptor 2 (Cardiac) (RYR2) interaction partners

  1. Studies indicate that the ryanodine receptors (RyRs: RyR1 (show RYR1 ELISA Kits), RyR2, RyR3 (show RYR3 ELISA Kits)) and inositol 1,4,5-trisphosphate receptors (IP3Rs: IP3R1 (show ITPR1 ELISA Kits), IP3R2 (show ITPR2 ELISA Kits), IP3R3 (show ITPR3 ELISA Kits)) are the major Ca(2 (show CA2 ELISA Kits)+) release channels (CRCs) on the endo/sarcoplasmic reticulum (ER/SR).

  2. although the EF-hand domain is not required for RyR2 activation by cytosolic Ca(2 (show CA2 ELISA Kits)+), it plays an important role in luminal Ca(2 (show CA2 ELISA Kits)+) activation and SOICR

  3. Half of the RYR2 mutations in catecholaminergic polymorphic ventricular tachycardia cohort were de novo, and most of the remaining mutations were inherited from mothers.

  4. A deletion of exon 3 of the RYR2 gene was found in a family with catecholaminergic polymorphic ventricular tachycardia.

  5. G357S_RyR2 mutation in the cardiac ryanodine receptor was identified in 179 family members with Catecholaminergic polymorphic ventricular tachycardia and in 6 Sudden cardiac death cases.

  6. We propose a mechanism in which RYR2 sequence variants result in aberrant stress-induced calcium release into the mitochondria of autonomic neurons, resulting in an increased risk to develop autonomic/functional disease such as cyclic vomiting syndrome.

  7. Our study identifies a significant role of RyR2 rs3766871 minor allele for increased susceptibility to VT/VF in a population of implanted with a cardioverter defibrillator patients with heart failure.

  8. unlike RyR1 (show RYR1 ELISA Kits) normal WT RyR2 does not bind dantrolene in spite of the fact that the RyR1 (show RYR1 ELISA Kits) dantrolene-binding site (residues 590-609) is conserved in RyR2

  9. How phosphorylation of RyR (show RYR1 ELISA Kits) affects channel activity and whether proteins such as the FK-506 binding proteins (FKBP12 and FKBP12.6 (show FKBP1B ELISA Kits)) are involved in heart failure

  10. induced Pluripotent Stem Cell-derived cardiomyocytes are useful for investigating the similarities/differences in the pathophysiological consequences of RyR2 versus CASQ2 (show CASQ2 ELISA Kits) mutations underlying Catecholaminergic polymorphic ventricular tachycardia.

Mouse (Murine) Ryanodine Receptor 2 (Cardiac) (RYR2) interaction partners

  1. Inhibition of RyR2 phosphorylation can suppress sarcoplasmic reticulum Ca(2 (show CA2 ELISA Kits)+) leak in mdx (show DMD ELISA Kits) mouse hearts in part by reducing RyR2 oxidation.

  2. Interacting network of the gap junction protein connexin43 (show GJA1 ELISA Kits), which includes Ryr2 and Cox1 (show COX1 ELISA Kits), is modulated by ischemia and reperfusion in the heart.

  3. While CASQ2 (show CASQ2 ELISA Kits) stabilizes RyR2 rendering it refractory in the diastolic phase, HRC (show HRC ELISA Kits) enhances RyR2 activity facilitating RyR2 recovery from refractoriness.

  4. These results provide no evidence that the H29D mutation enhances the cytosolic Ca2 (show CA2 ELISA Kits)+ activation of RyR2.

  5. CaMK2d (show CAMK2B ELISA Kits)-dependent phosphorylation of RyR2-S2814 is significant in cardiomyopathy, independent of hypertrophy, induced by prolonged beta-adrenergic receptor stimulation.

  6. RyR2 activity determines the potency of open-state blockers flecainide and R-propafenone for suppressing arrhythmogenic Ca2 (show CA2 ELISA Kits)+ waves in cardiomyocytes.

  7. Flecainide (1 mum) rescues the RyR2-P2328S atrial arrhythmogenic phenotype by restoring compromised INa (show INA ELISA Kits) and lambda, changes recently attributed to increased sarcoplasmic reticular Ca(2 (show CA2 ELISA Kits)+) release.

  8. The data suggest that the uneven distribution of dyads or calcium release sites within the cells resulting from an overall reduction in RyR2 content may contribute to the poor cardiac performance and early death of Ryr2 (ADA/ADA (show ADA ELISA Kits)) mice

  9. Data indicate that leaky ryanodine receptor 2 cardiac calcium release channel RyR2 cause mitochondrial Ca2 (show CA2 ELISA Kits)+ overload and dysfunction in heart failure (HF).

  10. Simultaneous detection of GFP-RyR2 clusters and Ca(2 (show CA2 ELISA Kits)+) sparks showed that Ca(2 (show CA2 ELISA Kits)+) sparks originated exclusively from RyR2 clusters. Ca(2 (show CA2 ELISA Kits)+) sparks from RyR2 clusters induced no detectable changes in mitochondrial Ca(2 (show CA2 ELISA Kits)+) level

RYR2 Antigen Profile

Antigen Summary

This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.

Gene names and symbols associated with RYR2

  • ryanodine receptor 2 (cardiac) (RYR2) antibody
  • ryanodine receptor 2-like (LOC537376) antibody
  • cardiac ryanodine receptor (RYR-2) antibody
  • ryanodine receptor 2 (cardiac) (Ryr2) antibody
  • ryanodine receptor 2, cardiac (Ryr2) antibody
  • 9330127I20Rik antibody
  • ARVC2 antibody
  • ARVD2 antibody
  • RyR antibody
  • RYR-2 antibody
  • RYR2 antibody
  • VTSIP antibody

Protein level used designations for RYR2

cardiac muscle ryanodine receptor , ryanodine receptor 2 (cardiac) , ryanodine receptor 2-like , Ca2+ release channel , cardiac muscle ryanodine receptor-calcium release channel , cardiac muscle-type ryanodine receptor , ryanodine receptor 2 , type 2 ryanodine receptor , cardiac ryanodine receptor 2 , cardiac-type ryanodine receptor , islet-type ryanodine receptor , kidney-type ryanodine receptor , ryanodine receptor type II , calcium release channel , ryanodine receptor type 2

GENE ID SPECIES
457846 Pan troglodytes
100028207 Monodelphis domestica
100057437 Equus caballus
100406916 Callithrix jacchus
537376 Bos taurus
100009536 Oryctolagus cuniculus
403615 Canis lupus familiaris
100731307 Cavia porcellus
6262 Homo sapiens
689560 Rattus norvegicus
20191 Mus musculus
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