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May have a role in a signaling pathway. Additionally we are shipping SASH1 Antibodies (67) and and many more products for this protein.
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SASH1 acts through NOTCH1 (show NOTCH1 Proteins) and its inhibitor DLK1 (show DLK1 Proteins) in a three-dimensional model of lumenogenesis involving CEACAM1 (show CEACAM1 Proteins).
SASH1 is cleaved by caspase-3 (show CASP3 Proteins) following Ultraviolet C-induced apoptosis.
a novel p53 (show TP53 Proteins)/POMC (show POMC Proteins)/Galphas (show GNAS Proteins)/SASH1 autoregulatory positive feedback loop is regulated by SASH1 mutations to induce pathological hyperpigmentation phenotype.
Overexpression of SASH1 inhibits TGF-beta1 (show TGFB1 Proteins)-induced EMT (show ITK Proteins).
Overexpression of SASH1 suppressed the expression of Shh (show SHH Proteins).
The loss or inhibition of SASH1 expression may play an important role in thyroid cancer development, invasion, and metastasis.
Two SNPs were significantly associated with rotator cuff tearing, residing in SAP30BP (show SAP30BP Proteins) on chromosome 17 and SASH1 on chromosome 6.
SASH1 expression is increased in atherosclerotic carotids in smokers and its silencing affects endothelial angiogenic functions
SASH1 expression strongly correlated with glioma grades, showing higher expression at a lower grade.
Data suggest that SASH1 (SAM and SH3 domain-containing protein 1) should be added to the list of genes responsible for autosomal-dominant and -recessive genodermatosis.
SASH1 acts to assemble a signaling complex downstream of TLR4 (show TLR4 Proteins) to activate early endothelial responses to receptor activation.
Not expressed in the investigated haematopoietic cell lines, while transcripts were found in whole splenic B-cells from both wild type and Btk (show BTK Proteins)-defective mice.
May have a role in a signaling pathway. Could act as a tumor suppressor.
SAM and SH3 domain containing 1
, SAM and SH3 domain-containing protein 1-like
, SAM and SH3 domain-containing protein 1
, proline-glutamate repeat-containing protein
, putative adapter and scaffold protein 1