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Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Additionally we are shipping SAR1A Antibodies (48) and SAR1A Proteins (17) and many more products for this protein.
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Data indicate that hydroxyurea (HU) induces SAR1 (show IQGAP1 ELISA Kits) protein expression, which in turn activates gamma-globin (show HBG1 ELISA Kits) expression, predominantly through the Gialpha/JNK (show MAPK8 ELISA Kits)/Jun (show JUN ELISA Kits) pathway.
although Sar1A antagonizes the lipoprotein secretion-promoting activity of Sar1B (show SAR1B ELISA Kits), both isoforms modulate the expression of genes encoding cholesterol biosynthetic enzymes and the synthesis of cholesterol de novo.
Sar1 (show IQGAP1 ELISA Kits) mutant proteins added to metaphase-arrested Xenopus laevis egg extracts cause dramatic effects on membrane organization.
the behavior of the human of Sar1A and Sar1B (show SAR1B ELISA Kits), a key component of the COPII family of vesicle coat proteins, was examined.
Sedlin (show TRAPPC2 ELISA Kits) bound and promoted efficient cycling of Sar1 (show IQGAP1 ELISA Kits), a guanosine triphosphatase that can constrict membranes, and thus allowed nascent carriers to grow and incorporate procollagen prefibrils.
lipid-directed and tether-assisted Sar1 (show IQGAP1 ELISA Kits) organization controls membrane constriction to regulate ER export.
the intracellular trafficking of hCaR (show CXADR ELISA Kits) from the endoplasmic reticulum is Sar1 (show IQGAP1 ELISA Kits)-dependent via coat protein (show GOLPH3 ELISA Kits) complex-II vesicles.
The Sec31 (show EXOC1 ELISA Kits) fragment stimulates GAP activity of Sec23/24, and a convergence of Sec31 (show EXOC1 ELISA Kits) and Sec23 residues at the Sar1 (show IQGAP1 ELISA Kits) GTPase (show RACGAP1 ELISA Kits) active site explains how GTP (show AK3 ELISA Kits) hydrolysis is triggered leading to COPII coat (show SEC23A ELISA Kits) disassembly.
Sar 1 (show IQGAP1 ELISA Kits) H79G mutants efficiently blocked the plasma membrane trafficking of the Kir3.1 (show KCNJ3 ELISA Kits)/Kir3.4 (show KCNJ5 ELISA Kits) complex however they did not block the Gbeta1gamma2/Kir3.1 (show KCNJ3 ELISA Kits) interaction.
Kir6.2 (show KCNJ11 ELISA Kits) contains a di-acidic endoplasmic reticulum exit signal, which promotes endoplasmic reticulum exit via a process that requires Sar1 (show IQGAP1 ELISA Kits).
Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Required to maintain SEC16A localization at discrete locations on the ER membrane perhaps by preventing its dissociation. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining endoplasmic reticulum exit sites (ERES) (By similarity).
GTP-binding protein Sar1A
, GTP-binding protein SAR1a
, GTP-binding protein SAR1A
, SAR1a gene homolog 1
, COPII-associated small GTPase
, SAR1 gene homolog A