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SATB2 encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. Additionally we are shipping SATB2 Proteins (4) and many more products for this protein.
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Human Polyclonal SATB2 Primary Antibody for IHC, ELISA - ABIN1003123
Dickinson, Kohwi-Shigematsu: Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential. in Molecular and cellular biology 1995
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Human Polyclonal SATB2 Primary Antibody for EIA, IHC (p) - ABIN500676
Szemes, Gyorgy, Paweletz, Dobi, Agoston: Isolation and characterization of SATB2, a novel AT-rich DNA binding protein expressed in development- and cell-specific manner in the rat brain. in Neurochemical research 2006
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Human Polyclonal SATB2 Primary Antibody for ICC, IF - ABIN4352126
Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006
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Human Polyclonal SATB2 Primary Antibody for EIA, IHC (p) - ABIN500674
Dobreva, Chahrour, Dautzenberg, Chirivella, Kanzler, Fariñas, Karsenty, Grosschedl: SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. in Cell 2006
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Human Polyclonal SATB2 Primary Antibody for EIA, WB - ABIN954675
McGovern, Gardet, Törkvist, Goyette, Essers, Taylor, Neale, Ong, Lagacé, Li, Green, Stevens, Beauchamp, Fleshner, Carlson, DAmato, Halfvarson, Hibberd, Lördal, Padyukov, Andriulli, Colombo, Latiano et al.: Genome-wide association identifies multiple ulcerative colitis susceptibility loci. ... in Nature genetics 2010
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Human Polyclonal SATB2 Primary Antibody for ICC, IF - ABIN4352127
Nodin, Johannesson, Wangefjord, OConnor, Lindquist, Uhlén, Jirström, Eberhard: Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer. in Diagnostic pathology 2012
Case Reports: cutaneous osteoblastic osteosarcomas positive for SATB2.
these results suggest miR (show MLXIP Antibodies)-31 inhibited triple negative breast cancer cells migration and invasion through suppressing SATB2 expression.
SATB2 regulates the mitosis of cell cycle and affects G1 cell cycle via interaction with CDK2 (show CDK2 Antibodies).
Low expression of SATB2 is associated with colorectal cancer.
Ovarian tumors with mucinous or endometrioid features that express SATB2 are unlikely to be of primary ovarian origin and more likely to be of colorectal/appendiceal origin.
SATB2 expression increased anchorage-independent growth and cell migration in human bronchial epithelial cells
Data suggest that MIRN-33a-5p is highly induced by TNFa (show TNF Antibodies) and BMP-2 (show BMP2 Antibodies) in bone marrow stromal cells; anti-osteogenic TNFa (show TNF Antibodies) down-regulates SATB2 expression indirectly; pro-osteogenic BMP-2 (show BMP2 Antibodies) up-regulates SATB2 expression directly.
SATB2 is a sensitive marker for hindgut well-differentiated neuroendocrine tumors though it is not entirely specific.
We found that IGFBP6 (show IGFBP6 Antibodies) and SATB2 were significantly down-regulated in HIV-infected CEM*174 cells and 3 different cohorts of HIV/AIDS patients while their promoters were predominantly hyper-methylated compared with normal controls.
data suggest that SATB2 functions as a tumor suppressor in the development and progression of clear cell renal cell carcinoma (show MOK Antibodies)
Data show that Satb2 is required by both callosal projection neurons and subcerebral projection neurons for proper differentiation and axon pathfinding.
Satb2 and Fezf2 (show FEZF2 Antibodies) regulation promotes subcerebral projection neuron identity in the developing cerebral cortex
Satb2 may also be related to the establishment of species-specific neuropeptide co-phenotypes during postnatal development.
Target genes of miR (show MLXIP Antibodies)-27a ware significantly up-regulated in Satb2-overexpressing cells.
A comprehensive overview of Satb2 expression in the adult mouse brain.
The Satb2 proteins are dispensable for X chromosome inactivation in mice.
the CB(1 (show CNR1 Antibodies)) receptor contributes to the generation of deep-layer cortical neurons by coupling endocannabinoid signals from the neurogenic niche to the intrinsic proneurogenic Ctip2 (show BCL11B Antibodies)/Satb2 axis
Our results indicate a cell autonomous and non-cell autonomous role for Satb2 in regulating the adhesive and/or repulsive properties of cerebral pyramidal neurons.
Genetic evidence obtained in the mouse confirmed the importance of SATB2 regulation by miR (show MLXIP Antibodies)-34b/c
SATB2 may play a crucial role in protecting against oxidative stress-induced (show SQSTM1 Antibodies) osteoblast apoptosis.
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.
DNA-binding protein SATB2
, special AT-rich sequence-binding protein 2
, special AT-rich sequence binding protein
, SATB homeobox 2
, special AT-rich sequence binding protein 2
, SATB family member 2
, KIAA1034-like DNA binding protein
, two cut domains-containing homeodomain protein