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SATB2 encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. Additionally we are shipping SATB2 Antibodies (84) and many more products for this protein.
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Human SATB2 Protein expressed in Wheat germ - ABIN2752928
Nodin, Johannesson, Wangefjord, OConnor, Lindquist, Uhlén, Jirström, Eberhard: Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer. in Diagnostic pathology 2012
Overexpression of SATB2 repressed the expression of extracellular signal-regulated kinase 5 (ERK5 (show MAPK7 Proteins)), and activation of ERK5 (show MAPK7 Proteins) restored the SATB2-induced inhibition of proliferation and migration in gastric cancer.
this study shows that SATB2 can be used as an additional marker with similar sensitivity and specificity as CK20 (show KRT20 Proteins) for the diagnosis of Merkel cell carcinoma
Case Reports: cutaneous osteoblastic osteosarcomas positive for SATB2.
these results suggest miR (show MLXIP Proteins)-31 inhibited triple negative breast cancer cells migration and invasion through suppressing SATB2 expression.
SATB2 regulates the mitosis of cell cycle and affects G1 cell cycle via interaction with CDK2 (show CDK2 Proteins).
Low expression of SATB2 is associated with colorectal cancer.
Ovarian tumors with mucinous or endometrioid features that express SATB2 are unlikely to be of primary ovarian origin and more likely to be of colorectal/appendiceal origin.
SATB2 expression increased anchorage-independent growth and cell migration in human bronchial epithelial cells
Data suggest that MIRN-33a-5p is highly induced by TNFa (show TNF Proteins) and BMP-2 (show BMP2 Proteins) in bone marrow stromal cells; anti-osteogenic TNFa (show TNF Proteins) down-regulates SATB2 expression indirectly; pro-osteogenic BMP-2 (show BMP2 Proteins) up-regulates SATB2 expression directly.
SATB2 is a sensitive marker for hindgut well-differentiated neuroendocrine tumors though it is not entirely specific.
results suggest that expression of Sp7 (show SP7 Proteins) during the early stage of Satb2-induced osteogenic differentiation of BMSCs is regulated by miR (show MLXIP Proteins)-27a.
Data show that Satb2 is required by both callosal projection neurons and subcerebral projection neurons for proper differentiation and axon pathfinding.
Satb2 and Fezf2 (show FEZF2 Proteins) regulation promotes subcerebral projection neuron identity in the developing cerebral cortex
Satb2 may also be related to the establishment of species-specific neuropeptide co-phenotypes during postnatal development.
Target genes of miR (show MLXIP Proteins)-27a ware significantly up-regulated in Satb2-overexpressing cells.
A comprehensive overview of Satb2 expression in the adult mouse brain.
The Satb2 proteins are dispensable for X chromosome inactivation in mice.
the CB(1 (show CNR1 Proteins)) receptor contributes to the generation of deep-layer cortical neurons by coupling endocannabinoid signals from the neurogenic niche to the intrinsic proneurogenic Ctip2/Satb2 axis
Our results indicate a cell autonomous and non-cell autonomous role for Satb2 in regulating the adhesive and/or repulsive properties of cerebral pyramidal neurons.
Genetic evidence obtained in the mouse confirmed the importance of SATB2 regulation by miR (show MLXIP Proteins)-34b/c
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.
DNA-binding protein SATB2
, special AT-rich sequence-binding protein 2
, special AT-rich sequence binding protein
, SATB homeobox 2
, special AT-rich sequence binding protein 2
, SATB family member 2
, KIAA1034-like DNA binding protein
, two cut domains-containing homeodomain protein