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SATB2 encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. Additionally we are shipping SATB2 Proteins (4) and many more products for this protein.
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Human Polyclonal SATB2 Primary Antibody for ICC, IF - ABIN4352126
Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006
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Human Polyclonal SATB2 Primary Antibody for IHC, ELISA - ABIN1003122
Dickinson, Kohwi-Shigematsu: Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential. in Molecular and cellular biology 1995
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Human Polyclonal SATB2 Primary Antibody for IHC, ELISA - ABIN1003123
Szemes, Gyorgy, Paweletz, Dobi, Agoston: Isolation and characterization of SATB2, a novel AT-rich DNA binding protein expressed in development- and cell-specific manner in the rat brain. in Neurochemical research 2006
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Human Polyclonal SATB2 Primary Antibody for IP - ABIN315852
Liu, Xu, Yang, Zhong, Song, Li, Hu, Chen, Hu, Han, Zeng: Decreased expression of SATB2: a novel independent prognostic marker of worse outcome in laryngeal carcinoma patients. in PLoS ONE 2012
Human Polyclonal SATB2 Primary Antibody for ICC, IF - ABIN4352127
Nodin, Johannesson, Wangefjord, OConnor, Lindquist, Uhlén, Jirström, Eberhard: Molecular correlates and prognostic significance of SATB1 expression in colorectal cancer. in Diagnostic pathology 2012
our data reveal that SATB2 in alveolar bone mesenchymal stem cells (AB-BMSCs) associates with their age-related properties, and prevents AB-BMSCs senescence via maintaining Nanog expression.
SATB2 is frequently expressed in appendiceal mucinous neoplasms. In the context of a mucinous neoplasm involving the ovary, any SATB2 positivity should raise the possibility of appendiceal origin.
our results strongly indicate that the crosstalk between p38 (show CRK Antibodies) and Akt (show AKT1 Antibodies) pathways can determine special AT-rich sequence-binding protein 2 expression and epithelial character of non-small-cell lung carcinoma cells
SATB2 immunohistochemistry is not useful in supporting urothelial versus gastrointestinal or endocervical origin in the differential diagnosis of glandular lesions of the bladder/urinary tract.
we report a exon frameshift mutation in SATB2 in a 15-year-old patient with cleft palate, apparent ID, mild facial dysmorphism, and low weight with additional features of osteoporosis, fractures, progressive tibial bowing, and scoliosis. it provides further evidence of a single-nucleotide, potentially dominant-negative SATB2 allele in association with phenotypes beyond those typically associated with deletion of the gene
Indicate that beta-catenin (show CTNNB1 Antibodies) and SATB2 are useful immunohistochemical markers for differentiating between pulmonary enteric adenocarcinoma and metastatic colorectal carcinoma.
SATB2 can directly bind to the regulatory elements in the genetic loci of several stem cell markers and consequently inhibit the progression of CRC (show CALR Antibodies) by negatively regulating stemness of CRC (show CALR Antibodies) cells
miR (show MLXIP Antibodies)-599 directly binds to the 3'untranslated region of SATB2, and western blotting showed that miR (show MLXIP Antibodies)-599 suppresses the expression of SATB2 at the protein level. This study indicates that miR (show MLXIP Antibodies)-599 promotes proliferation and invasion of non-small cell lung cancer cell lines via SATB2.
SATB2 is a highly sensitive marker for osteosarcomatous differentiation in gynecologic tract
Although SATB2 immunoexpression helps to distinguish osteosarcoma from their mimickers, the identification of malignant osteoid matrix formation and the integration of clinical and radiological data remain the corner stone of osteosarcoma diagnosis and as yet no antibody has equalled the diagnostic value of this important morphologic hallmark.
Satb2 is a genetic determinant that mediates proper circuit development in a core sensory-to-motor spinal network.
Data indicate two special AT-rich sequence-binding protein 2 (SATB2) sequence variants in two unrelated patients presenting with Rett-like phenotypes.
results suggest that expression of Sp7 (show SP7 Antibodies) during the early stage of Satb2-induced osteogenic differentiation of BMSCs is regulated by miR (show MLXIP Antibodies)-27a.
Data show that Satb2 is required by both callosal projection neurons and subcerebral projection neurons for proper differentiation and axon pathfinding.
Satb2 and Fezf2 (show FEZF2 Antibodies) regulation promotes subcerebral projection neuron identity in the developing cerebral cortex
Satb2 may also be related to the establishment of species-specific neuropeptide co-phenotypes during postnatal development.
Target genes of miR (show MLXIP Antibodies)-27a ware significantly up-regulated in Satb2-overexpressing cells.
A comprehensive overview of Satb2 expression in the adult mouse brain.
The Satb2 proteins are dispensable for X chromosome inactivation in mice.
the CB(1 (show CNR1 Antibodies)) receptor contributes to the generation of deep-layer cortical neurons by coupling endocannabinoid signals from the neurogenic niche to the intrinsic proneurogenic Ctip2 (show BCL11B Antibodies)/Satb2 axis
This gene encodes a DNA binding protein that specifically binds nuclear matrix attachment regions. The encoded protein is involved in transcription regulation and chromatin remodeling. Defects in this gene are associated with isolated cleft palate and mental retardation. Alternate splicing results in multiple transcript variants that encode the same protein.
DNA-binding protein SATB2
, special AT-rich sequence-binding protein 2
, special AT-rich sequence binding protein
, SATB homeobox 2
, special AT-rich sequence binding protein 2
, SATB family member 2
, KIAA1034-like DNA binding protein
, two cut domains-containing homeodomain protein