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Involved in the modulation of neuronal aggregation.
demonstrated SCO-spondin expression at relevant steps of gestation in the placenta
expression of SCO-spondin is not restricted to the subcommissural organ but it also occurs in the floor plate, a key structure participating in neuronal differentiation and patterning of the neural tube
Results indicate that 5HT (show DDC ELISA Kits) down-regulates SCO-spondin biosynthesis but apparently not its release, and suggest that 5HT (show DDC ELISA Kits) may exert the effect on the SCO (show SNAI1 ELISA Kits) via the cerebrospinal fluid.
Involved in the modulation of neuronal aggregation. May be involved in developmental events during the formation of the central nervous system (By similarity).
SCO protein, thrombospondin domain containing
, SCO-spondin homolog (Bos taurus)
, subcommissural organ spondin