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anti-SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) Antibodies

Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Additionally we are shipping SCO2 Proteins (11) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SCO2 100126824 Q8VCL2
SCO2 9997 O43819
SCO2    
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Top anti-SCO2 Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB SCO2 Antibody (C-term)  western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the SCO2 antibody detected the SCO2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry of SCO2 in human liver tissue with this product at 2.5 μg/ml. Western blot analysis of SCO2 in human liver tissue lysate with this product at (A) 0.5, (B) 1 and (C) 2 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   100 μg Log in to see 15 to 19 Days
$455.07
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 11 to 13 Days
$541.80
Details
Human Rabbit Un-conjugated IHC, WB   200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of SCO2 in human liver tissue lysate with SCO2 antibody at (A) 0.5, (B) 1 and (C) 2 µg/mL. 0.1 mg Log in to see 2 to 3 Days
$330.00
Details

SCO2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)


Human , ,
,

, , , , ,
Rat (Rattus)


Top referenced anti-SCO2 Antibodies

  1. Human Polyclonal SCO2 Primary Antibody for IHC, ELISA - ABIN1003127 : Glerum, Shtanko, Tzagoloff: SCO1 and SCO2 act as high copy suppressors of a mitochondrial copper recruitment defect in Saccharomyces cerevisiae. in The Journal of biological chemistry 1996 (PubMed)
    Show all 4 references for ABIN1003127

More Antibodies against SCO2 Interaction Partners

Mouse (Murine) SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) interaction partners

  1. Data suggest that physical exercise attenuates age-related changes in mitochondrial COX biogenesis and p53 activity targeting SCO2 and mitochondria, and thereby induces antisenescent and protective effects in cardiac muscle.

  2. Results describe the tissue distribution of SCO1 and SCO2 in mouse and human tissues.

  3. To understand the biological role of SCO2, mice harboring both a Sco2 knock-out (KO) allele and a Sco2 knock-in (KI) E129K allele, corresponding to the common E140K mutation in humans, were studied.

  4. findings show that p53 modulates the balance between the utilization of respiratory and glycolytic pathways; identifed Synthesis of Cytochrome c Oxidase 2 (SCO2) as the downstream mediator of this effect

Human SCO2 Cytochrome C Oxidase Assembly Protein (SCO2) interaction partners

  1. Geranylgeranoic acid increased the SCO2 gene expression, which might enhance aerobic respiration.

  2. oncoprotein HBXIP (show HBXIP Antibodies) enhances glucose metabolism reprogramming through suppressing SCO2 and PDHA1 (show PDHA1 Antibodies) in breast cancer

  3. Cooperation between COA6 and SCO2 in COX2 (show COX2 Antibodies) maturation during cytochrome c (show CYCS Antibodies) oxidase assembly links two mitochondrial cardiomyopathies.

  4. Sco1 is a metallochaperone that selectively transfers Cu(I) ions based on loop recognition, whereas Sco2 is a copper-dependent thiol reductase of the cysteine ligands in the oxidase.

  5. Letter/Case Report: SCO2 mutations resulting in Leigh disease revealed at autopsy.

  6. mutation in LRPAP1 is associated with high myopia. Further studies are expected to evaluate the pathogenicity of the variants in CTSH, LEPREL1, ZNF644, SLC39A5, and SCO2.

  7. COX20 cooperates with SCO1 (show SCO1 Antibodies) and SCO2 to mature COX2 (show COX2 Antibodies) and promote the assembly of cytochrome c (show CYCS Antibodies) oxidase.

  8. alpha-particle-induced bystander effect is regulated by p53 and its downstream SCO2 in the irradiated hepatoma cells

  9. oroxylin A could increase protein and mRNA expression of TP53-induced glycolysis and apoptosis regulator (TIGAR (show C12orf5 Antibodies)) and synthesis of cytochrome c oxidase 2 (show COX2 Antibodies) (SCO2), which are the key metabolic modulators regulated by p53 (show TP53 Antibodies).

  10. Autosomal recessive mutations in SCO2 are known to be associated with COX (show COX8A Antibodies) deficiency recognized as fatal infantile cardio-encephalomyopathy

SCO2 Antigen Profile

Protein Summary

Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors\; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy.

Gene names and symbols associated with SCO2

  • SCO cytochrome oxidase deficient homolog 2 (yeast) (SCO2) antibody
  • SCO cytochrome oxidase deficient homolog 2 (yeast) (Sco2) antibody
  • SCO2 cytochrome c oxidase assembly protein (SCO2) antibody
  • CEMCOX1 antibody
  • MYP6 antibody
  • SCO1L antibody

Protein level used designations for SCO2

protein SCO2 homolog, mitochondrial , SCO cytochrome oxidase deficient homolog 2 , cytochrome oxidase deficient homolog 2

GENE ID SPECIES
100125923 Bos taurus
100126824 Mus musculus
9997 Homo sapiens
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