SET Binding Protein 1 (SETBP1) ELISA Kits

SETBP1 encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. Additionally we are shipping SETBP1 Antibodies (27) and SETBP1 Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SETBP1 SETBP1 26040 Q9Y6X0
Anti-Mouse SETBP1 SETBP1 240427 Q9Z180
Anti-Rat SETBP1 SETBP1 291423  
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More ELISA Kits for SETBP1 Interaction Partners

Human SET Binding Protein 1 (SETBP1) interaction partners

  1. SETBP1 is a major oncogene (show RAB1A ELISA Kits) in myeloid neoplasms, which cooperates with various genetic events and causes distinct phenotypes of myelodysplastic/myeloproliferative neoplasms and secondary acute myeloid leukemia (show BCL11A ELISA Kits).

  2. Results indicate a genotype-phenotype correlation in germline SET binding protein 1 (SETBP1) mutations spanning a molecular, cellular and clinical phenotype.

  3. AML (show RUNX1 ELISA Kits) with RUNX1 (show RUNX1 ELISA Kits)/RUNX1T1 (show RUNX1T1 ELISA Kits) rearrangement displayed c.2903C>T alteration in the mutational hotspot of SETBP1.

  4. Data describe a new recurrent chromosome translocation, t(12;18)(q14-q15;q12-21), in lipomas and osteochondrolipoma resulting in HMGA2-SETBP1 fusion which suggest a close developmental relationship between the two tumor types.

  5. we described a patient not fulfilling the clinical criteria and showing mutation in SETBP1, we suggest that the facial gestalt associated with neurological involvement would be sufficient to indicate molecular analysis of this particular gene.

  6. Correlation of myelodysplastic syndromes with i(17)(q10 (show EIF2C2 ELISA Kits)) and TP53 (show TP53 ELISA Kits) and SETBP1 mutations.

  7. The SETBP1 and ASXL1 (show ASXL1 ELISA Kits) mutations have pathogenetic roles in CSF3R (show CSF3R ELISA Kits)-mutated chronic neutrophilic leukemia.

  8. SETBP1 mutation might not be involved in the leukemogenisis of acute lymphoblastic leukemia

  9. SETBP1 mutations are critical drivers of ASXL1 (show ASXL1 ELISA Kits)-mutated myelodysplastic syndrome.

  10. mutation analysis of CSF3R (show CSF3R ELISA Kits), SETBP1 and CALR (show CALR ELISA Kits) should be included in the diagnostic criteria for chronic neutrophilic leukemia

Mouse (Murine) SET Binding Protein 1 (SETBP1) interaction partners

  1. We demonstrated that Nup98 (show NUP98 ELISA Kits)-TopIIbeta and Nup98 (show NUP98 ELISA Kits)-SETBP1 negatively regulate the XPO1 (show XPO1 ELISA Kits)-mediated protein export. Our results will contribute to the understanding of the molecular mechanism by which the Nup98 (show NUP98 ELISA Kits)-fusion proteins induce tumorigenesis.

  2. Setbp1 overexpression also causes transcriptional repression of critical hematopoiesis regulator gene Runx1 (show RUNX1 ELISA Kits)

  3. Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 (show HOXA9 ELISA Kits) and Hoxa10 (show HOXA10 ELISA Kits).

SETBP1 Antigen Profile

Antigen Summary

This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals. The encoded protein has been shown to bind the SET nuclear oncogene which is involved in DNA replication. Mutations in this gene are associated with Schinzel-Giedion midface retraction syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SETBP1

  • SET binding protein 1 (SETBP1) antibody
  • SET binding protein 1 (setbp1) antibody
  • SET binding protein 1 (Setbp1) antibody
  • C130092E12 antibody
  • mKIAA0437 antibody
  • Seb antibody
  • SETBP1 antibody

Protein level used designations for SETBP1

A20-binding inhibitor of NF-kappaB activation 2 , SET binding protein 1 , SET-binding protein-like , SET-binding protein

617265 Bos taurus
416376 Gallus gallus
490472 Canis lupus familiaris
100053128 Equus caballus
100737551 Sus scrofa
455390 Pan troglodytes
529737 Bos taurus
796785 Danio rerio
100013797 Monodelphis domestica
100080512 Ornithorhynchus anatinus
100125067 Xenopus (Silurana) tropicalis
100228402 Taeniopygia guttata
100356045 Oryctolagus cuniculus
100385749 Callithrix jacchus
100449471 Pongo abelii
100568022 Anolis carolinensis
100601169 Nomascus leucogenys
26040 Homo sapiens
240427 Mus musculus
291423 Rattus norvegicus
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