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Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. Additionally we are shipping SETDB2 Antibodies (67) and SETDB2 Proteins (4) and many more products for this protein.
Results indicate that the IgE-associated AT/G polymorphism (rs386770867) regulates transcription of SETDB2.
these findings identify Setdb2 as a novel regulator of the immune system in acute respiratory viral infection.
Results provide evidence that CLLD8/KMT1F is recruited to heterochromatin regions and contributes in vivo to the deposition of trimethyl marks in concert with SUV39H1 (show SUV39H1 ELISA Kits)/KMT1A.SUV39H1/KMT1A (show SUV39H1 ELISA Kits).
Results suggest that a Setdb2-mediated regulatory crosstalk between the type I interferons and NF-kappaB (show NFKB1 ELISA Kits) pathways is a mechanism for virus-induced susceptibility to bacterial superinfection.
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003
chronic lymphocytic leukemia deletion region 8
, chronic lymphocytic leukemia deletion region gene 8 protein
, histone-lysine N-methyltransferase SETDB2
, lysine N-methyltransferase 1F
, Setdb2-Phf11-1-Phf11-2 fusion