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SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) ELISA Kits

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. Additionally we are shipping SETD7 Antibodies (86) and SETD7 Proteins (11) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SETD7 80854 Q8WTS6
Anti-Mouse SETD7 SETD7 73251 Q8VHL1
Anti-Rat SETD7 SETD7 689954  
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Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.054 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days

More ELISA Kits for SETD7 Interaction Partners

Human SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. Lysine methylation by SETD7 is important for the fine-tuning of reactive oxygen species signaling through its regulation on pro-inflammatory responses.

  2. Knock-down of SETD7 causes differentiation defects in human embryonic stem cell including delay in both the silencing of pluripotency-related genes and the induction of differentiation genes.

  3. Unleashed expression of Mdm2 (show MDM2 ELISA Kits) in cancer patients with diminished expression of Set7/9 is associated with poor survival outcome.

  4. Based on our results miR (show MLXIP ELISA Kits)-153 inhibits proliferation and suppresses EMT (show ITK ELISA Kits) and the invasive potential of ovarian cancer cells through downregulation of SET7 and ZEB2 (show ZEB2 ELISA Kits), supporting the pursuit of miR (show MLXIP ELISA Kits)-153 as a potential target for ovarian cancer intervention.

  5. Findings indicate the regulation of Wnt/beta-catenin signaling and the role of SET domain-containing protein 7/9 (SET7/9) in cancer cells.

  6. Set7-induced epigenetic changes contribute to vascular dysfunction in patients with T2DM.

  7. SET9 enriches at hypoxia response elements sites of HIF-1 (show HIF1A ELISA Kits) responsive glycolytic genes and stabilizes HIF-1alpha (show HIF1A ELISA Kits) at these sites in hypoxia.

  8. Set7/9 is a potential biomarker in tumour cells and is associated with overexpressed E2F1 (show E2F1 ELISA Kits) activity.

  9. Results show that histone-lysine N-methyltransferase Set7 facilitates hepatitis C virus (HCV) replication through the attenuation of interferon-alpha (IFN-alpha (show IFNA ELISA Kits)) signaling pathways and IFN-related effectors.

  10. Set7-dependent gene expression changes that occurred independent of H3K4m1 may involve transcription factor lysine methylation events.

Mouse (Murine) SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. SETD7 is required for Wnt (show WNT2 ELISA Kits)-driven intestinal tumorigenesis and regeneration. SETD7-dependent methylation of YAP (show YAP1 ELISA Kits) facilitates Wnt (show WNT2 ELISA Kits)-induced nuclear accumulation of beta-catenin (show CTNNB1 ELISA Kits).

  2. SET7/9 regulates Nos2 expression through methylation of H3K4 in beta cells.

  3. Data indicate that the ability of transcription factor Pdx1 (show PDX1 ELISA Kits) to regulate genes in beta cells is partially dependent upon its methylation by methyltransferase Set7/9.

  4. study found that Set7 is a modifier of the Hippo pathway. Mice that lack Set7 have a larger progenitor compartment in the intestine, coinciding with increased expression of Yes-associated protein target genes.

  5. The response to hyperglycemia in vascular endothelial cells involves Set7 mediated changes in chromatin remodeling and gene expression.

  6. Set7/9-mediated methylation of p53 (show TP53 ELISA Kits) does not represent a major regulatory event and does not appreciably control p53 (show TP53 ELISA Kits) activity in vivo.

  7. Set7/9 is dispensable for p53 (show TP53 ELISA Kits) function in the mouse.

  8. Define a biological function for Set7 in muscle differentiation and provide a molecular mechanism by which Set7 modulates myogenic transcription factors during muscle differentiation.

  9. Pdx1 (show PDX1 ELISA Kits)-dependent Set7/9 expression may be crucial to enhancing chromatin accessibility and transcription of beta-cell genes.

  10. Methylation of p53 (show TP53 ELISA Kits) by Set7 mediates p53 (show TP53 ELISA Kits) acetylation and activity in vivo.

SETD7 Antigen Profile

Antigen Summary

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the -K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Gene names and symbols associated with SETD7

  • SET domain containing (lysine methyltransferase) 7 (SETD7) antibody
  • SET domain containing (lysine methyltransferase) 7 (setd7) antibody
  • SET domain containing (lysine methyltransferase) 7 (Setd7) antibody
  • 1600028F23Rik antibody
  • H3K4MT antibody
  • KMT7 antibody
  • mKIAA1717 antibody
  • Set7 antibody
  • Set7/9 antibody
  • SET9 antibody
  • zgc:92330 antibody
  • zgc:101860 antibody

Protein level used designations for SETD7

H3-K4-HMTase SETD7 , SET domain-containing protein 7 , histone H3-K4 methyltransferase SETD7 , histone H3-lysine 4-specific methyltransferase , histone-lysine N-methyltransferase SETD7 , lysine N-methyltransferase 7 , H3-K4 methyltransferase

80854 Homo sapiens
436729 Danio rerio
73251 Mus musculus
689954 Rattus norvegicus
476079 Canis lupus familiaris
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