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SET Domain Containing (Lysine Methyltransferase) 7 Proteins (SETD7)

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. Additionally we are shipping SETD7 Antibodies (86) and SETD7 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SETD7 80854 Q8WTS6
SETD7 73251 Q8VHL1
Rat SETD7 SETD7 689954  
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Top SETD7 Proteins at antibodies-online.com

Showing 9 out of 11 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,001.17
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$365.64
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 1 to 2 Days
$455.00
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Log in to see 1 to 2 Days
$455.00
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 19 Days
$785.40
Details

SETD7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
,
Mouse (Murine)

Top referenced SETD7 Proteins

  1. Human SETD7 Protein expressed in Escherichia coli (E. coli) - ABIN2004086 : Martens, Verlaan, Kalkhoven, Zantema: Cascade of distinct histone modifications during collagenase gene activation. in Molecular and cellular biology 2003 (PubMed)

More Proteins for SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) Interaction Partners

Human SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. study identified a novel locus associated with serum lycopene concentrations and results raise a number of possibilities regarding the nature of the relationship between SETD7 and lycopene, both independently associated with prostate cancer.

  2. Lysine methylation by SETD7 is important for the fine-tuning of reactive oxygen species signaling through its regulation on pro-inflammatory responses.

  3. Knock-down of SETD7 causes differentiation defects in human embryonic stem cell including delay in both the silencing of pluripotency-related genes and the induction of differentiation genes.

  4. Unleashed expression of Mdm2 (show MDM2 Proteins) in cancer patients with diminished expression of Set7/9 is associated with poor survival outcome.

  5. Based on our results miR (show MLXIP Proteins)-153 inhibits proliferation and suppresses EMT (show ITK Proteins) and the invasive potential of ovarian cancer cells through downregulation of SET7 and ZEB2, supporting the pursuit of miR (show MLXIP Proteins)-153 as a potential target for ovarian cancer intervention.

  6. Findings indicate the regulation of Wnt/beta-catenin signaling and the role of SET domain-containing protein 7/9 (SET7/9) in cancer cells.

  7. Set7-induced epigenetic changes contribute to vascular dysfunction in patients with T2DM.

  8. SET9 enriches at hypoxia response elements sites of HIF-1 (show HIF1A Proteins) responsive glycolytic genes and stabilizes HIF-1alpha (show HIF1A Proteins) at these sites in hypoxia.

  9. Set7/9 is a potential biomarker in tumour cells and is associated with overexpressed E2F1 (show E2F1 Proteins) activity.

  10. Results show that histone-lysine N-methyltransferase Set7 facilitates hepatitis C virus (HCV) replication through the attenuation of interferon-alpha (IFN-alpha (show IFNA Proteins)) signaling pathways and IFN-related effectors.

Mouse (Murine) SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. SETD7 is required for Wnt (show WNT2 Proteins)-driven intestinal tumorigenesis and regeneration. SETD7-dependent methylation of YAP (show YAP1 Proteins) facilitates Wnt (show WNT2 Proteins)-induced nuclear accumulation of beta-catenin (show CTNNB1 Proteins).

  2. SET7/9 regulates Nos2 expression through methylation of H3K4 in beta cells.

  3. Data indicate that the ability of transcription factor Pdx1 (show PDX1 Proteins) to regulate genes in beta cells is partially dependent upon its methylation by methyltransferase Set7/9.

  4. study found that Set7 is a modifier of the Hippo pathway. Mice that lack Set7 have a larger progenitor compartment in the intestine, coinciding with increased expression of Yes-associated protein target genes.

  5. The response to hyperglycemia in vascular endothelial cells involves Set7 mediated changes in chromatin remodeling and gene expression.

  6. Set7/9-mediated methylation of p53 (show TP53 Proteins) does not represent a major regulatory event and does not appreciably control p53 (show TP53 Proteins) activity in vivo.

  7. Set7/9 is dispensable for p53 (show TP53 Proteins) function in the mouse.

  8. Define a biological function for Set7 in muscle differentiation and provide a molecular mechanism by which Set7 modulates myogenic transcription factors during muscle differentiation.

  9. Pdx1 (show PDX1 Proteins)-dependent Set7/9 expression may be crucial to enhancing chromatin accessibility and transcription of beta-cell genes.

  10. Methylation of p53 (show TP53 Proteins) by Set7 mediates p53 (show TP53 Proteins) acetylation and activity in vivo.

SETD7 Protein Profile

Protein Summary

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the -K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Gene names and symbols associated with SETD7

  • SET domain containing (lysine methyltransferase) 7 (SETD7)
  • SET domain containing (lysine methyltransferase) 7 (setd7)
  • SET domain containing (lysine methyltransferase) 7 (Setd7)
  • 1600028F23Rik protein
  • H3K4MT protein
  • KMT7 protein
  • mKIAA1717 protein
  • Set7 protein
  • Set7/9 protein
  • SET9 protein
  • zgc:92330 protein
  • zgc:101860 protein

Protein level used designations for SETD7

H3-K4-HMTase SETD7 , SET domain-containing protein 7 , histone H3-K4 methyltransferase SETD7 , histone H3-lysine 4-specific methyltransferase , histone-lysine N-methyltransferase SETD7 , lysine N-methyltransferase 7 , H3-K4 methyltransferase

GENE ID SPECIES
80854 Homo sapiens
436729 Danio rerio
73251 Mus musculus
689954 Rattus norvegicus
476079 Canis lupus familiaris
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