anti-SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) Antibodies

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. Additionally we are shipping SETD7 Proteins (11) and SETD7 Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SETD7 80854 Q8WTS6
SETD7 73251 Q8VHL1
SETD7 689954  
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Top anti-SETD7 Antibodies at antibodies-online.com

Showing 10 out of 101 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-SET9 Ctr Pab (ABIN387997) is used in Western blot to detect SET9 in mouse brain tissue lysate. Western blot analysis of SET9(arrow) using rabbit polyclonal SET9 Antibody(ABIN387997). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the SET9 gene (Lane 2) (Origene Technologies). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated EIA, IHC (p), WB Immunoblot analysis.,.Recombinant SET7/9 was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-SET7/9(1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicated SET7/9(~50Da). 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated ChIP, IHC (p), WB Western blot analysis for Set7/9 using ABIN252611 at 1:500 on 20 ug of HeLa whole cell lysate. Western Blot: SETD7/9 Antibody [ABIN2526114] - Whole cell extract from MCF7 cells. Image from verified customer review. 0.2 mL Log in to see 7 to 9 Days
$317.63
Details
Bat Rabbit Un-conjugated IHC (p), WB Anti-SETD7 / SET7 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN960912 dilution 1:100. 50 μL Log in to see 7 to 9 Days
$451.00
Details
Bat Rabbit Un-conjugated WB 100 μg Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot: SETD7 Antibody [ABIN4085698] - Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded), 293T (T; 50 mcg), and mouse NIH3T3 (M; 50 mcg) cells. ABIN4085698 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. Immunohistochemistry-Paraffin: SETD7 Antibody [ABIN4085698] - FFPE section of human prostate carcinoma. Affinity purified rabbit anti-SET7 used at a dilution of 1:250 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Mouse Un-conjugated ELISA   100 μg Log in to see 20 to 21 Days
$218.90
Details

SETD7 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-SETD7 Antibodies

  1. Cow (Bovine) Polyclonal SETD7 Primary Antibody for WB - ABIN2783571 : Subramanian, Jia, Kapoor-Vazirani, Powell, Collins, Sharma, Peng, Cheng, Vertino: Regulation of estrogen receptor alpha by the SET7 lysine methyltransferase. in Molecular cell 2008 (PubMed)

  2. Human Polyclonal SETD7 Primary Antibody for ChIP, IHC (p) - ABIN252611 : Narayanan, Ruyechan, Kristie: The coactivator host cell factor-1 mediates Set1 and MLL1 H3K4 trimethylation at herpesvirus immediate early promoters for initiation of infection. in Proceedings of the National Academy of Sciences of the United States of America 2007 (PubMed)

More Antibodies against SETD7 Interaction Partners

Human SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. Methylation at K436 and K595 respectively by Set7 increases the stability and DNA binding ability of Gli3 (show GLI3 Antibodies), resulting in an enhancement of Shh (show SHH Antibodies) signaling activation.

  2. the methyltransferase Set9 potentiates TGF-beta (show TGFB1 Antibodies) signaling by targeting Smad7 (show SMAD7 Antibodies), an inhibitory downstream effector.

  3. SETD7 plays a critical role in HCC (show FAM126A Antibodies), and its immunohistochemistry signature provides potential clinical significance for personalized prediction of HCC (show FAM126A Antibodies) prognosis.

  4. These findings underscore the role of KMT7 as an important monomethyltransferase regulating HIV transcription through Tat (show TAT Antibodies).

  5. High SET7 expression is associated with breast cancer.

  6. SET7 was required for GATA1 (show GATA1 Antibodies)-induced breast tumor angiogenesis and growth in nude mice. GATA1 (show GATA1 Antibodies) and SET7 are independent poor prognostic factors in breast cancer.

  7. SET7/SET9-mediated YY1 (show YY1 Antibodies) methylation was shown to be involved in YY1 (show YY1 Antibodies)-regulated gene transcription and cell proliferation.

  8. These results demonstrate that S...O chalcogen bonds contribute to AdoMet (show MAT1A Antibodies) recognition and can enable methyltransferases to distinguish between substrate and product.

  9. Reduced expression of SET7 is associated with gastric cancer progression.

  10. study identified a novel locus associated with serum lycopene concentrations and results raise a number of possibilities regarding the nature of the relationship between SETD7 and lycopene, both independently associated with prostate cancer.

Mouse (Murine) SET Domain Containing (Lysine Methyltransferase) 7 (SETD7) interaction partners

  1. the methyltransferase Set9 potentiates TGF-beta (show TGFB1 Antibodies) signaling by targeting Smad7 (show SMAD7 Antibodies), an inhibitory downstream effector.

  2. SETD7 plays an important role in intestinal epithelial cell (IEC) biology during infection.

  3. We observe Set7-mediated modification of serum response factor (SRF) and mono-methylation of histone H4 lysine 4 (H3K4me1) regulate gene expression. We conclude the broad substrate specificity of Set7 serves to control key transcriptional networks in embryonic stem cells.

  4. SETD7 is required for Wnt (show WNT2 Antibodies)-driven intestinal tumorigenesis and regeneration. SETD7-dependent methylation of YAP (show YAP1 Antibodies) facilitates Wnt (show WNT2 Antibodies)-induced nuclear accumulation of beta-catenin (show CTNNB1 Antibodies).

  5. SET7/9 regulates Nos2 expression through methylation of H3K4 in beta cells.

  6. Data indicate that the ability of transcription factor Pdx1 (show PDX1 Antibodies) to regulate genes in beta cells is partially dependent upon its methylation by methyltransferase Set7/9.

  7. study found that Set7 is a modifier of the Hippo pathway. Mice that lack Set7 have a larger progenitor compartment in the intestine, coinciding with increased expression of Yes-associated protein target genes.

  8. The response to hyperglycemia in vascular endothelial cells involves Set7 mediated changes in chromatin remodeling and gene expression.

  9. Set7/9-mediated methylation of p53 (show TP53 Antibodies) does not represent a major regulatory event and does not appreciably control p53 (show TP53 Antibodies) activity in vivo.

  10. Set7/9 is dispensable for p53 (show TP53 Antibodies) function in the mouse.

SETD7 Antigen Profile

Protein Summary

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the -K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Gene names and symbols associated with SETD7

  • SET domain containing (lysine methyltransferase) 7 (SETD7) antibody
  • SET domain containing (lysine methyltransferase) 7 (setd7) antibody
  • SET domain containing (lysine methyltransferase) 7 (Setd7) antibody
  • 1600028F23Rik antibody
  • H3K4MT antibody
  • KMT7 antibody
  • mKIAA1717 antibody
  • Set7 antibody
  • Set7/9 antibody
  • SET9 antibody
  • zgc:92330 antibody
  • zgc:101860 antibody

Protein level used designations for SETD7

H3-K4-HMTase SETD7 , SET domain-containing protein 7 , histone H3-K4 methyltransferase SETD7 , histone H3-lysine 4-specific methyltransferase , histone-lysine N-methyltransferase SETD7 , lysine N-methyltransferase 7 , H3-K4 methyltransferase

GENE ID SPECIES
80854 Homo sapiens
436729 Danio rerio
73251 Mus musculus
689954 Rattus norvegicus
476079 Canis lupus familiaris
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