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SET Domain Containing (Lysine Methyltransferase) 8 Proteins

(SET Domain Containing (Lysine Methyltransferase) 8 (SETD8))

Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes (By similarity).

recommended

SETD8 Protein (AA 195-352) (His tag) (ABIN7125068)

SETD8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

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recommended

SETD8 Protein (AA 1-393) (Strep Tag) (ABIN3093468)

Crystallography grade SETD8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

SETD8 Protein (AA 1-349) (Strep Tag) (ABIN3134954)

Crystallography grade SETD8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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SET Domain Containing (Lysine Methyltransferase) 8 Proteins by Grade

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SET Domain Containing (Lysine Methyltransferase) 8 Proteins by Origin

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SET Domain Containing (Lysine Methyltransferase) 8 Proteins by Source

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Popular SET Domain Containing (Lysine Methyltransferase) 8 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

SETD8 Protein (AA 195-352) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7125068

Quantity 50 μg

Datasheet Datasheet

SETD8 Protein (AA 1-393) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3093468

Quantity 1 mg

Datasheet Datasheet

SETD8 Protein (AA 1-349) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3134954

Quantity 1 mg

Datasheet Datasheet

SETD8 Protein (AA 195-352) (His tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN5855179

Quantity 50 μg

Datasheet Datasheet

SETD8 Protein (GST tag)

Reactivity Human

Source Baculovirus infected Insect Cells, Insect cells (Sf9)

Validations

Cat. No. ABIN6700508

Quantity 50 μg

Datasheet Datasheet

SETD8 Protein (AA 1-336) (His tag)

Reactivity Xenopus tropicalis

Source Yeast

Validations

Cat. No. ABIN1618348

Quantity 1 mg

Datasheet Datasheet

SETD8 Protein (AA 1-352) (His tag)

Reactivity Cow

Source Yeast

Validations

Cat. No. ABIN1623210

Quantity 1 mg

Datasheet Datasheet

SETD8 Protein (AA 1-429) (His tag)

Reactivity Schizosaccharomyces pombe

Source Yeast

Validations

Cat. No. ABIN1591430

Quantity 1 mg

Datasheet Datasheet

Aliases for SET Domain Containing (Lysine Methyltransferase) 8 Proteins

lysine methyltransferase 5A (KMT5A) Proteins
lysine methyltransferase 5A (Kmt5a) Proteins
lysine methyltransferase 5Ab (kmt5ab) Proteins
lysine methyltransferase 5A S homeolog (kmt5a.S) Proteins
lysine methyltransferase 5Aa (kmt5aa) Proteins
2410195B05Rik Proteins
AA617402 Proteins
AW536475 Proteins
KMT5A Proteins
kmt5a Proteins
kmt5a-a Proteins
PR-Set7 Proteins
PR-SET7 Proteins
Pr-set7 Proteins
RGD1305893 Proteins
SET07 Proteins
SET8 Proteins
set8a Proteins
Setd8 Proteins
setd8 Proteins
setd8-a Proteins
setd8a Proteins
setd8b Proteins
wu:fc23f12 Proteins
wu:fj33f02 Proteins
zgc:153719 Proteins
zgc:171649 Proteins

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Popular SET Domain Containing (Lysine Methyltransferase) 8 Proteins

Aliases for SET Domain Containing (Lysine Methyltransferase) 8 Proteins

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