anti-SET Domain Containing 1A (SETD1A) Antibodies

SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4.

list all antibodies Gene Name GeneID UniProt
SETD1A 9739 O15047
SETD1A 233904  
SETD1A    
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Top anti-SETD1A Antibodies at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB Host: Rabbit Target Name: SETD1A Sample Type: Breast Tumor lysates Antibody Dilution: 1.0ug/ml 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), IHC, WB Detection of Human hSET1 by Western Blot. Samples: Whole cell lysate (WCL, 100 or 200 mcg) and nuclear extract (NE, 100 and 200 mcg) from HEK293T cells. Antibody: ABIN151989 used at the indicated concentrations. Detection: Chemiluminescence with an exposure time of 1 minute. Immunohistochemistry-Paraffin: SETD1A Antibody [ABIN151989] - Human colon carcinoma. Antibody used at a dilution of 1:1,000. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated ChIP, IHC (p), IP, IHC, WB Detection of Human hSET1 by Western Blot and Immunoprecipitation. Samples: A. Whole cell lysate (WCL, 100 or 200 mcg) and nuclear extract (NE, 100 and 200 mcg) from 293T cells. B. Nuclear extract (5 mg) from 293T cells. Antibodies: A. ABIN151990 used at the indicated concentrations for WB. B. Affinity purified anti-hSET1 antibodies ABIN151989, ABIN151990, ABIN151991, and another hSET1 antibody used at 5 mcg/5mg NE for IP. Immunoprecipitated hSET1 was detected using ABIN151990 at 0.2 mcg/ml. Detection: Chemiluminescence with exposure times of 30 seconds (A) and 10 seconds (B). Chromatin Immunoprecipitation: SETD1A Antibody [ABIN151990] - ChIP-chip scatter plot of anti-hSET1 (ABIN151990) enriched DNA binding sites versus input reference DNA. A. 10 mcg of ABIN151990 was used to immunoprecipitate chromatin from K562 cells according to Ren et al (Genes Dev. 2002 16: 245-256). Immunoprecipitated DNA and reference DNA were amplified via ligation-mediated PCR and the products labeled with fluorescent dUTPs. The labeled ChIP and reference DNA were pooled, hybridized to a DNA microarray, and analyzed. Data points below the +3 SD curve (red line) represent significantly enriched binding sites. B. As a control, a similar experiment was performed using normal rabbit IgG. Compared to the anti-hSET1 ChIP, normal rabbit IgG showed little enrichment. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated WB SETD1A Antibody (Center) (ABIN1881793) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the SETD1A antibody detected the SETD1A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p) Immunocytochemistry/Immunofluorescence: SETD1A Antibody [NBP1-81513] - Staining of human cell line A-431 shows positivity in nucleus but not nucleoli. Immunohistochemistry-Paraffin: SETD1A Antibody [NBP1-81513] - Staining of human duodenum shows strong nuclear positivity. 0.1 mL Log in to see 10 to 13 Days
$439.69
Details
Mouse Rabbit Un-conjugated ELISA, WB 50 μL Log in to see 2 to 3 Days
$185.00
Details
Human Mouse Un-conjugated IHC, WB Western Blot: SETD1A Antibody (7B7) [NBP2-45790] - Analysis of HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SETD1A. Immunohistochemistry: SETD1A Antibody (7B7) [NBP2-45790] - Analysis of Human tonsil tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min) 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Mouse Un-conjugated IHC (p), WB   100 μL Log in to see 7 to 9 Days
$493.17
Details
Human Rabbit Un-conjugated WB Western blot analysis in 293 cell line lysates (35ug/lane). 400 μL Log in to see 2 to 3 Days
$515.63
Details

SETD1A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine) ,


Dog (Canine) ,


Top referenced anti-SETD1A Antibodies

  1. Human Polyclonal SETD1A Primary Antibody for WB - ABIN1881793 : Lee, Skalnik: CpG-binding protein (CXXC finger protein 1) is a component of the mammalian Set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex. in The Journal of biological chemistry 2005 (PubMed)
    Show all 6 references for 1881793

  2. Human Polyclonal SETD1A Primary Antibody for ChIP, IHC (p) - ABIN151990 : Lee, Tate, You, Skalnik: Identification and characterization of the human Set1B histone H3-Lys4 methyltransferase complex. in The Journal of biological chemistry 2007 (PubMed)
    Show all 5 references for 151990

  3. Human Polyclonal SETD1A Primary Antibody for ICC, IF - ABIN151989 : Zager, Johnson: Renal ischemia-reperfusion injury upregulates histone-modifying enzyme systems and alters histone expression at proinflammatory/profibrotic genes. in American journal of physiology. Renal physiology 2009 (PubMed)
    Show all 2 references for 151989

  4. Human Polyclonal SETD1A Primary Antibody for ICC, IF - ABIN4353047 : Cho, Shimazu, Toyokawa, Daigo, Maehara, Hayami, Ito, Masuda, Ikawa, Field, Tsuchiya, Ohnuma, Ponder, Yoshida, Nakamura, Hamamoto: Enhanced HSP70 lysine methylation promotes proliferation of cancer cells through activation of Aurora kinase B. in Nature communications 2012 (PubMed)

More Antibodies against SETD1A Interaction Partners

Human SET Domain Containing 1A (SETD1A) interaction partners

  1. data indicate that Setd1a and NURF (show RBBP4 Antibodies) complexes are specifically targeted to and coordinately regulate erythroid promoter chromatin dynamics during erythroid lineage differentiation

  2. Targeted Disruption of the Interaction between WD-40 Repeat Protein 5 (show CAPS Antibodies) (WDR5 (show WDR5 Antibodies)) and Mixed Lineage Leukemia (MLL (show MLL Antibodies))/SET1 Family Proteins Specifically Inhibits MLL1 and SETd1A Methyltransferase Complexes.

  3. Study provides evidence that increased Set1 binding at the promoter induces aberrant epigenetic alterations and up-regulates CREMA in systemic lupus erythematosus.

  4. Collectively called the WRAD complex, these proteins are pivotal to the HMT (show HNMT Antibodies) activity of the SET1 complexes. Recent reports highlight the novel non-canonical functions of WRAD in cellular processes other than its well-studied role in histone methylation and gene expression.

  5. Given the critical tumor suppressor role of p53 (show TP53 Antibodies), SETD1A-mediated suppression of this pathway (even in the absence of p53 (show TP53 Antibodies) mutations), would be predicted to have profound consequences on tumorigenesis.

  6. Findings provide evidence that SET1A cooperates with CUDR to play a positive potential role during hepatocarcinogenesis and hepatocyte-like stem cells' malignant transformation epigenetically.

  7. Loss-of-function variants in SETD1A cause a range of neurodevelopmental disorders in a Finnish population.

  8. Set1 role in cellular reprogramming and its interactions with Dpy30 (show DPY30 Antibodies),Myc (show MYC Antibodies),Sox2 (show SOX2 Antibodies) and Ash2l (show ASH2L Antibodies) reprogramming factors

  9. This study demonstrated that SETD1A mutation showing the highest statistical significance in Autism and Schizophrenia.

  10. suppresses BTG2 (show BTG2 Antibodies) expression through its induction of several BTG2 (show BTG2 Antibodies)-targeting miRNAs

Mouse (Murine) SET Domain Containing 1A (SETD1A) interaction partners

  1. data indicate that Setd1a and NURF (show RBBP4 Antibodies) complexes are specifically targeted to and coordinately regulate erythroid promoter chromatin dynamics during erythroid lineage differentiation

  2. miR (show MLXIP Antibodies)-29a mimic transfection lowered collagen 1alpha1, DNMT1 (show DNMT1 Antibodies), DNMT3b (show DNMT3B Antibodies) and SET1A expression in hepatic stellate cells.

  3. our study provides valuable information on the molecular interactions between OSKM(Oct4 (show POU5F1 Antibodies), Sox2 (show SOX2 Antibodies), Klf4 (show KLF4 Antibodies), and Myc (show MYC Antibodies)) and cofactors and molecular mechanisms for the functional importance of Set1a in ESCs (show NR2E3 Antibodies) and early development

  4. revealed a critical role of Setd1a and its mediated epigenetic modifications in regulating the IgH rearrangement and B-cell development

  5. The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b (show SETD1B Antibodies) becomes essential after gastrulation.

  6. embryonic stem cells lacking Cfp1 (CXXC1 (show CXXC1 Antibodies)(-/-)) are viable but show increased levels of global histone H3K4 methylation, suggesting that Cfp1 (show CXXC1 Antibodies) functions to inhibit or restrict the activity of the Setd1A histone H3K4 methyltransferase complex.

  7. mNSC1 lacks protein-coding capacity

SETD1A Antigen Profile

Protein Summary

SET1A is a component of a histone methyltransferase (HMT) complex that produces mono-, di-, and trimethylated histone H3 at Lys4. The complex is the analog of the S. cerevisiae Set1/COMPASS complex (Lee and Skalnik, 2005

Gene names and symbols associated with SETD1A

  • SET domain containing 1A (SETD1A) antibody
  • SET domain containing 1A (setd1a) antibody
  • SET domain containing 1A (Pat9b_4052) antibody
  • SET domain containing 1A (Setd1a) antibody
  • BC010250 antibody
  • KMT2F antibody
  • mKIAA0339 antibody
  • mNSC1 antibody
  • Nsccn1 antibody
  • NV15594 antibody
  • Set1 antibody
  • Set1A antibody

Protein level used designations for SETD1A

SET domain containing 1A , histone-lysine N-methyltransferase SETD1A , histone-lysine N-methyltransferase SETD1-like protein , histone-lysine N-methyltransferase SETD1A-like , SET domain-containing protein 1A , hSET1A , lysine N-methyltransferase 2F , set1/Ash2 histone methyltransferase complex subunit SET1 , non-selective cation channel 1

GENE ID SPECIES
468101 Pan troglodytes
556535 Danio rerio
782887 Bos taurus
10074221 Pantoea sp. At-9b
100063523 Equus caballus
100121025 Nasonia vitripennis
100432076 Pongo abelii
100511747 Sus scrofa
100602268 Nomascus leucogenys
9739 Homo sapiens
233904 Mus musculus
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