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anti-SET Domain Containing 8 Pseudogene 1 (SETD8P1) Antibodies

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3.

list all antibodies Gene Name GeneID UniProt
SETD8P1 80854 Q8WTS6
SETD8P1 73251 Q8VHL1
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Top anti-SET Domain Containing 8 Pseudogene 1 Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-SET7 Pab(ABIN387998) in mouse brain tissue lysate (35 µg/lane). SET7(arrow) was detected using the purified polyclonal antibody (1:70 dilution). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.05 mg Log in to see 2 to 3 Days
$515.63
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$415.58
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$415.58
Details
Human Rabbit Un-conjugated ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit HRP ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit Un-conjugated IHC, ELISA, WB   200 μL Log in to see 11 to 16 Days
$532.71
Details

SETD8P1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human
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Mouse (Murine)


Top referenced anti-SET Domain Containing 8 Pseudogene 1 Antibodies

  1. Human Polyclonal SETD8P1 Primary Antibody for WB - ABIN387998 : Chuikov, Kurash, Wilson, Xiao, Justin, Ivanov, McKinney, Tempst, Prives, Gamblin, Barlev, Reinberg: Regulation of p53 activity through lysine methylation. in Nature 2004 (PubMed)
    Show all 5 references for ABIN387998

More Antibodies against SET Domain Containing 8 Pseudogene 1 Interaction Partners

Human SET Domain Containing 8 Pseudogene 1 (SETD8P1) interaction partners

  1. High SET7 (show SETD7 Antibodies) expression is associated with breast cancer.

  2. SET7 (show SETD7 Antibodies) was required for GATA1 (show GATA1 Antibodies)-induced breast tumor angiogenesis and growth in nude mice. GATA1 (show GATA1 Antibodies) and SET7 (show SETD7 Antibodies) are independent poor prognostic factors in breast cancer.

  3. SET7/SET9-mediated YY1 (show YY1 Antibodies) methylation was shown to be involved in YY1 (show YY1 Antibodies)-regulated gene transcription and cell proliferation.

  4. These results demonstrate that S...O chalcogen bonds contribute to AdoMet (show MAT1A Antibodies) recognition and can enable methyltransferases to distinguish between substrate and product.

  5. Reduced expression of SET7 (show SETD7 Antibodies) is associated with gastric cancer progression.

  6. study identified a novel locus associated with serum lycopene concentrations and results raise a number of possibilities regarding the nature of the relationship between SETD7 (show SETD7 Antibodies) and lycopene, both independently associated with prostate cancer.

  7. Lysine methylation by SETD7 (show SETD7 Antibodies) is important for the fine-tuning of reactive oxygen species signaling through its regulation on pro-inflammatory responses.

  8. Knock-down of SETD7 (show SETD7 Antibodies) causes differentiation defects in human embryonic stem cell including delay in both the silencing of pluripotency-related genes and the induction of differentiation genes.

  9. Unleashed expression of Mdm2 (show MDM2 Antibodies) in cancer patients with diminished expression of Set7/9 is associated with poor survival outcome.

  10. Based on our results miR (show MLXIP Antibodies)-153 inhibits proliferation and suppresses EMT (show ITK Antibodies) and the invasive potential of ovarian cancer cells through downregulation of SET7 (show SETD7 Antibodies) and ZEB2 (show ZEB2 Antibodies), supporting the pursuit of miR (show MLXIP Antibodies)-153 as a potential target for ovarian cancer intervention.

Mouse (Murine) SET Domain Containing 8 Pseudogene 1 (SETD8P1) interaction partners

  1. SETD7 (show SETD7 Antibodies) is required for Wnt (show WNT2 Antibodies)-driven intestinal tumorigenesis and regeneration. SETD7 (show SETD7 Antibodies)-dependent methylation of YAP (show YAP1 Antibodies) facilitates Wnt (show WNT2 Antibodies)-induced nuclear accumulation of beta-catenin (show CTNNB1 Antibodies).

  2. SET7/9 regulates Nos2 expression through methylation of H3K4 in beta cells.

  3. Data indicate that the ability of transcription factor Pdx1 (show PDX1 Antibodies) to regulate genes in beta cells is partially dependent upon its methylation by methyltransferase Set7/9.

  4. study found that Set7 (show SETD7 Antibodies) is a modifier of the Hippo pathway. Mice that lack Set7 (show SETD7 Antibodies) have a larger progenitor compartment in the intestine, coinciding with increased expression of Yes-associated protein target genes.

  5. The response to hyperglycemia in vascular endothelial cells involves Set7 (show SETD7 Antibodies) mediated changes in chromatin remodeling and gene expression.

  6. Set7/9-mediated methylation of p53 (show TP53 Antibodies) does not represent a major regulatory event and does not appreciably control p53 (show TP53 Antibodies) activity in vivo.

  7. Set7/9 is dispensable for p53 (show TP53 Antibodies) function in the mouse.

  8. Define a biological function for Set7 (show SETD7 Antibodies) in muscle differentiation and provide a molecular mechanism by which Set7 (show SETD7 Antibodies) modulates myogenic transcription factors during muscle differentiation.

  9. Pdx1 (show PDX1 Antibodies)-dependent Set7/9 expression may be crucial to enhancing chromatin accessibility and transcription of beta-cell genes.

  10. Methylation of p53 (show TP53 Antibodies) by Set7 (show SETD7 Antibodies) mediates p53 (show TP53 Antibodies) acetylation and activity in vivo.

SET Domain Containing 8 Pseudogene 1 (SETD8P1) Antigen Profile

Protein Summary

Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the -K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation.

Gene names and symbols associated with SETD8P1

  • SET domain containing (lysine methyltransferase) 7 (SETD7) antibody
  • SET domain containing (lysine methyltransferase) 7 (Setd7) antibody
  • 1600028F23Rik antibody
  • H3K4MT antibody
  • KMT7 antibody
  • mKIAA1717 antibody
  • Set7 antibody
  • Set7/9 antibody
  • SET9 antibody

Protein level used designations for SETD8P1

H3-K4-HMTase SETD7 , SET domain-containing protein 7 , histone H3-K4 methyltransferase SETD7 , histone H3-lysine 4-specific methyltransferase , histone-lysine N-methyltransferase SETD7 , lysine N-methyltransferase 7 , H3-K4 methyltransferase

GENE ID SPECIES
80854 Homo sapiens
73251 Mus musculus
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