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SET Domain and Mariner Transposase Fusion Gene (SETMAR) ELISA Kits

SETMAR encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. Additionally we are shipping SETMAR Antibodies (33) and SETMAR Proteins (9) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SETMAR 6419 Q53H47
SETMAR 74729 Q80UJ9
SETMAR 500281 Q5I0M0
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Top SETMAR ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details
Rat
96 Tests Log in to see 11 to 13 Days
$875.60
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Cow
96 Tests Log in to see 11 to 13 Days
$1,029.60
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More ELISA Kits for SETMAR Interaction Partners

Human SET Domain and Mariner Transposase Fusion Gene (SETMAR) interaction partners

  1. The SET domain is needed for the 5' end of ss-overhang cleavage with fork and non-fork DNA without affecting the Metnase-DNA interaction. This domain has a positive role in restart of replication fork and the 5' end of ss-overhang cleavage.

  2. methylation of snRNP70 (show SNRNP70 ELISA Kits) by SETMAR regulates constitutive and/or alternative splicing

  3. Metnase may possess an important role in DNA repair, topoisomerase II (show TOP2 ELISA Kits) function, and the maintenance of stemness during colon cancer development.

  4. 293 T transfected with Metnase revealed a large number of rescued plasmids.

  5. found known and novel SETMAR splice variants to be significantly increased in acute myeloid leukemia (show BCL11A ELISA Kits)

  6. a single mutation DDN(610) --> DDD (show KRT5 ELISA Kits)(610), which restores the ancestral catalytic site, results in loss of function in Metnase

  7. phosphorylation of Metnase S495 differentiates between these two functions, enhancing DSB repair and repressing replication fork restart.

  8. Data show that DBN1 (show DBN1 ELISA Kits), SETMAR and HIG2 (show HILPDA ELISA Kits) are direct transcriptional targets of the SOX11 (show SOX11 ELISA Kits) protein.

  9. DNA repair protein (show ATRIP ELISA Kits) Metnase (also SETMAR), which has a SET histone methylase domain, localized to an induced DSB and directly mediated the formation of H3K36me2 near the induced DSB

  10. results establish Metnase as a key factor that promotes restart of stalled replication forks, and implicate Metnase in the repair of collapsed forks.

Mouse (Murine) SET Domain and Mariner Transposase Fusion Gene (SETMAR) interaction partners

  1. The suppression of Notch-1 (show NOTCH1 ELISA Kits) led to increased expression of Oct4 (show POU5F1 ELISA Kits) and Sox2 (show SOX2 ELISA Kits), but in decreased gene expression of cMET, Setmar and CD44 (show CD44 ELISA Kits).

  2. Metnase may have been selected for because it has a function opposing transposases and may thus play a key role in suppressing translocations that underlie oncogenicity.

SETMAR Antigen Profile

Antigen Summary

This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with SETMAR

  • SET domain and mariner transposase fusion gene (SETMAR) antibody
  • SET domain without mariner transposase fusion (SETMAR) antibody
  • SET domain without mariner transposase fusion (setmar) antibody
  • SET domain and mariner transposase fusion gene (setmar) antibody
  • SET domain without mariner transposase fusion (Setmar) antibody
  • 5830404F24Rik antibody
  • Etet2 antibody
  • HsMar1 antibody
  • Mar1 antibody
  • METNASE antibody
  • MGC151518 antibody
  • SETMAR antibody
  • zgc:172212 antibody

Protein level used designations for SETMAR

SET domain and mariner transposase fusion gene , histone-lysine N-methyltransferase SETMAR , SET domain and mariner transposase fusion , SET domain without mariner transposase fusion , metnase , histone-lysine N-methyltransferase SETMAR-like , SET domain and mariner transposase fusion gene-containing protein , SET domain and mariner transposase fusion gene-containing protein homolog , epidermal tumor expressed transcript 2

GENE ID SPECIES
427598 Gallus gallus
470738 Pan troglodytes
476549 Canis lupus familiaris
564575 Danio rerio
703880 Macaca mulatta
100135741 Xenopus (Silurana) tropicalis
100447656 Pongo abelii
100586616 Nomascus leucogenys
534913 Bos taurus
6419 Homo sapiens
511299 Bos taurus
74729 Mus musculus
500281 Rattus norvegicus
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