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anti-SET and MYND Domain Containing 3 (SMYD3) Antibodies

SMYD3 encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Additionally we are shipping SMYD3 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SMYD3 64754 Q9H7B4
SMYD3 69726 Q9CWR2
SMYD3 498295  
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Top anti-SMYD3 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SMYD3 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated ChIP, WB WB Suggested Anti-SMYD3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Stomach Quiescent human colon carcinoma HCT116 cultures were treated with 10 % FBS for three time points (0, 15, 30min) or (0, 30, 60min) were used in Matrix-ChIP and real-time PCR assays at EGR1 gene (Exon1) and 15kb upstream site. 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SMYD3 antibody (N-term) in CEM cell line lysates (35ug/lane). SMYD3 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SMYD3 antibody (N-term) (ABIN391518) in CEM cell line lysates (35 µg/lane). SMYD3 (arrow) was detected using the purified polyclonal antibody. SMYD3 Antibody (N-term) (ABIN391518) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB SMYD3 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- SMYD3 Antigen Affinity purified polyclonal antibody at 1 μg/mL. The immunohistochemical section was developed using SABC method Western blot analysis of SMYD3 expression in HELA whole cell lysates (lane 1) and COLO320 whole cell lysates (lane 2). SMYD3 at 55KD was detected using rabbit anti- SMYD3 Antigen Affinity purified polyclonal antibody at0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$527.15
Details

SMYD3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SMYD3 Antibodies

  1. Human Polyclonal SMYD3 Primary Antibody for EIA, WB - ABIN453382 : Zou, Wang, Yang, Luo, Xie, Xi: Knockdown of SMYD3 by RNA interference down-regulates c-Met expression and inhibits cells migration and invasion induced by HGF. in Cancer letters 2009 (PubMed)
    Show all 5 references for ABIN453382

  2. Cow (Bovine) Polyclonal SMYD3 Primary Antibody for WB - ABIN2784278 : Silva, Hamamoto, Kunizaki, Tsuge, Nakamura, Furukawa: Enhanced methyltransferase activity of SMYD3 by the cleavage of its N-terminal region in human cancer cells. in Oncogene 2008 (PubMed)

  3. Human Polyclonal SMYD3 Primary Antibody for FACS, IHC (p) - ABIN391518 : Barlési, Giaccone, Gallegos-Ruiz, Span, Lefesvre, Kruyt, Rodriguez: Genotype analysis of the VNTR polymorphism in the SMYD3 histone methyltransferase gene: lack of correlation with the level of histone H3 methylation in NSCLC tissues or with the risk of NSCLC. in International journal of cancer. Journal international du cancer 2008 (PubMed)

More Antibodies against SMYD3 Interaction Partners

Human SET and MYND Domain Containing 3 (SMYD3) interaction partners

  1. A novel HBx-interacting protein (show HBXIP Antibodies), SMYD3, was identified, leading to proposal of a novel mechanism of AP-1 (show FOSB Antibodies) activation in HBV-infected cells.

  2. Postulate that AdoMet (show MAT1A Antibodies) cofactor acts like a key and locks Smyd3 in a closed conformation.

  3. Results showed that SMYD3 is overexpressed in human glioma and contributes to glioma tumorigenicity through p53 (show TP53 Antibodies).

  4. SMYD3 interacts with the human positive coactivator 4 (PC4 (show IFRD1 Antibodies)) and that such interaction potentiates a group of genes whose expression is linked to cell proliferation and invasion.

  5. Results support a proto-oncogenic role for SMYD3 in prostate carcinogenesis, mainly due to its methyltransferase enzymatic activity.

  6. role of histone methyltransferase SMYD3 in tumors

  7. Loss of SMYD3-HSP90 (show HSP90 Antibodies) interaction leads to SMYD3 mislocalization within the nucleus, thereby losing its chromatin association. This results in reduction of SMYD3-mediated cell proliferation and, potentially, impairment of SMYD3's oncogenic activity.

  8. High SMYD3 and pSTAT3 expressions may indicate poor prognosis of patients with gastric cancer

  9. Results suggest that high expression of SMYD3 is related to the occurrence of esophageal squamous cell carcinoma. Also, its suppression promoted the expression of RIZ1 (show PRDM2 Antibodies) suggesting a signal transduction pathway between SMYD3 and RIZ1 (show PRDM2 Antibodies).

  10. SMYD3 and MMP-9 (show MMP9 Antibodies) may play important roles in tumor invasion, metastasis, and prognosis and could work as promising targets for prognostic prediction in gastric cancer.

Mouse (Murine) SET and MYND Domain Containing 3 (SMYD3) interaction partners

  1. The transcription-potentiating function of Smyd3 is restricted to a particular set of genes.

  2. Epigenetic control of Foxp3 (show FOXP3 Antibodies) by SMYD3 H3K4 histone methyltransferase controls iTreg development and regulates pathogenic T-cell responses during pulmonary viral infection.

  3. These findings indicate that SMYD3 plays an important role in early embryonic lineage commitment and peri (show POSTN Antibodies)-implantation development through the activation of lineage-specific genes.

  4. represent the proof of principle that SMYD3 is a druggable target

  5. methylation of MAP3K2 by SMYD3 increases MAP kinase signalling and promotes the formation of Ras-driven carcinomas

  6. SMYD3 depletion prevents muscle loss and fiber size decrease; findings reveal a mechanistic link between SMYD3/BRD4 (show BRD4 Antibodies)-dependent transcriptional regulation, muscle mass determination, and skeletal muscle atrophy

  7. SMYD3 encodes a histone methyltransferase involved in the proliferation of cancer cells.

SMYD3 Antigen Profile

Protein Summary

This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SMYD3

  • SET and MYND domain containing 3 (LOC100347516) antibody
  • SET and MYND domain containing 3 (SMYD3) antibody
  • SET and MYND domain containing 3 (Smyd3) antibody
  • 2410008A19Rik antibody
  • bA74P14.1 antibody
  • KMT3E antibody
  • Zmynd1 antibody
  • ZNFN3A1 antibody

Protein level used designations for SMYD3

SET and MYND domain containing 3 , SET and MYND domain-containing protein 3 , bA74P14.1 (novel protein) , histone-lysine N-methyltransferase SMYD3 , zinc finger MYND domain-containing protein 1 , zinc finger protein, subfamily 3A (MYND domain containing), 1 , zinc finger, MYND domain containing 1 , SET and MYND domain-containing 3

GENE ID SPECIES
100347516 Oryctolagus cuniculus
64754 Homo sapiens
100294707 Sus scrofa
616050 Bos taurus
69726 Mus musculus
498295 Rattus norvegicus
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