You are viewing an incomplete version of our website. Please click to reload the website as full version.

anti-SH2 Domain Protein 2A (SH2D2A) Antibodies

SH2D2A encodes an adaptor protein thought to function in T-cell signal transduction. Additionally we are shipping SH2 Domain Protein 2A Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SH2D2A 9047 Q9NP31
SH2D2A 310688  
SH2D2A 27371 Q9QXK9
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-SH2 Domain Protein 2A Antibodies at antibodies-online.com

Showing 10 out of 61 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB SH2D2A Antibody (Center) (ABIN651523) western blot analysis in MDA-MB435 cell line lysates (35 µg/lane). This demonstrates the SH2D2A antibody detected the SH2D2A protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Anti-SH2D2A mouse monoclonal antibody (ABIN2455606) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH2D2A (RC204162). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SH2D2A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SH2D2A. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB HEK293T cells transfected with either RC204162 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SH2D2A antibody (ABIN2455613), and then analyzed by flow cytometry. Anti-SH2D2A mouse monoclonal antibody (ABIN2455613) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY SH2D2A (RC204162). 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC204162 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-SH2D2A antibody (ABIN2455617), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SH2D2A (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SH2D2A. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HepG2 cells, using SH2D2A Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Human Rabbit Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 11 to 16 Days
$412.86
Details
Human Rabbit APC ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

SH2D2A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,
, ,
,
, , , , ,
Rat (Rattus)


Mouse (Murine) ,
, ,
,

Top referenced anti-SH2 Domain Protein 2A Antibodies

  1. Human Polyclonal SH2D2A Primary Antibody for WB - ABIN651523 : Lorentzen, Smestad, Lie, Oturai, Akesson, Saarela, Myhr, Vartdal, Celius, Sørensen, Hillert, Spurkland, Harbo: The SH2D2A gene and susceptibility to multiple sclerosis. in Journal of neuroimmunology 2008 (PubMed)

  2. Human Monoclonal SH2D2A Primary Antibody for FACS, IF - ABIN2455613 : Pandya, Leergaard, Dissen, Haraldsen, Spurkland: Expression of the T cell-specific adapter protein in human tissues. in Scandinavian journal of immunology 2014 (PubMed)

More Antibodies against SH2 Domain Protein 2A Interaction Partners

Human SH2 Domain Protein 2A (SH2D2A) interaction partners

  1. TSAD binds to and co-localizes with Nck (show NCK1 Antibodies). Expression of TSAD increases both Nck (show NCK1 Antibodies)-Lck (show LCK Antibodies) and Nck (show NCK1 Antibodies)-SLP-76 (show LCP2 Antibodies) interaction in T cells.

  2. The kinase Itk (show ITK Antibodies) and the adaptor TSAd change the specificity of the kinase Lck (show LCK Antibodies) in T cells by promoting the phosphorylation of Tyr192.

  3. Data indicate the expression pattern of T cell-specific adapter protein (TSAd) in various healthy lymphoid and non-lymphoid tissues.

  4. in chronic inflammatory demyelinating polyneuropathy we found an association with a homozygous genotype for a low repeat number of tandem GA in the SH2D2A gene

  5. TSAd, through its interaction with both Itk and Lck, primes Itk for Lck mediated phosphorylation and thereby regulates CXCL12 induced T cell migration and actin cytoskeleton rearrangements

  6. TSAd associates with laminin binding protein (show RPSA Antibodies) and mediates T lymphocyte migration during T cell activation

  7. TSAd appears to contribute to interleukin-2 (show IL2 Antibodies) synthesis at multiple different levels

  8. upon chemokine (show CCL1 Antibodies) stimulation, Lad (show DLD Antibodies) acts as an adaptor protein that links the G protein beta subunit (show GNB3 Antibodies) to the tyrosine kinases Lck (show LCK Antibodies) and Zap-70 (show ZAP70 Antibodies), thereby mediating T-cell migration

  9. SH2D2A expression is regulated both at the transcriptional and translational level.

  10. lymphocyte-specific protein tyrosine kinase (show LCK Antibodies) binds to T cell-specific adapter protein (TSAd) prolines and phosphorylates and interacts with the three C-terminal TSAd tyrosines

Mouse (Murine) SH2 Domain Protein 2A (SH2D2A) interaction partners

  1. Sh2d2a protein deficient mice display reduced clearance of Dm157 MCMV infection in the spleen.

  2. The kinase Itk (show ITK Antibodies) and the adaptor TSAd change the specificity of the kinase Lck (show LCK Antibodies) in T cells by promoting the phosphorylation of Tyr192.

  3. Results suggest a modulatory role for T cell specific adapter protein SH2D2A in T cell mediated immune surveillance of cancer.

  4. Data show that tyrosine phosphorylation of VEGF receptor 2 (VEGFR2) facilitates binding of VEGFR2 (show KDR Antibodies) to the Rous sarcoma (Src (show SRC Antibodies)) homology 2-domain of T cell-specific adaptor (TSAd), which in turn regulates VEGF (show VEGFA Antibodies)-induced activation of the c-Src tyrosine kinase (show CSK Antibodies).

  5. results show that TSAd, particularly the SH2 (show MYO15 Antibodies) domain of TSAd, is essential for the effector functions of T cells.

  6. TSAd, through its interaction with both Itk and Lck, primes Itk for Lck mediated phosphorylation and thereby regulates CXCL12 induced T cell migration and actin cytoskeleton rearrangements

  7. role of TSAd as a critical regulator of T cell death whose absence promotes systemic autoimmunity

  8. TSAd appears to contribute to interleukin-2 (show IL2 Antibodies) synthesis at multiple different levels

  9. The major role of T cell-specific adapter protein in peripheral T cell cytoplasm is for activation of LCK (show LCK Antibodies) protein tyrosine kinase (show YES1 Antibodies) at the outset of T cell receptor signal transduction

  10. Although Rlk/Itk-binding protein (RIBP) is coexpressed with related adaptor lymphocytes of unknown function X (ALX) protein on both T- and B-lymphocytes during cell development, no redundancy or synergy is found.

SH2 Domain Protein 2A (SH2D2A) Antigen Profile

Protein Summary

This gene encodes an adaptor protein thought to function in T-cell signal transduction. A related protein in mouse is responsible for the activation of lymphocyte-specific protein-tyrosine kinase and functions in downstream signaling. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with SH2D2A

  • SH2 domain containing 2A (SH2D2A) antibody
  • SH2 domain containing 2A (Sh2d2a) antibody
  • SH2 domain protein 2A (Sh2d2a) antibody
  • F2771 antibody
  • Lad antibody
  • Ribp antibody
  • SCAP antibody
  • Tsad antibody
  • VRAP antibody

Protein level used designations for SH2D2A

SH2 domain protein 2A , SH2 domain-containing protein 2A , T cell specific adapter protein TSAd , T lymphocyte specific adaptor protein , VEGF receptor-associated protein , Lck-associated adapter protein , Rlk/Itk-binding protein , T cell-specific adapter protein , p56Lck-associated adapter protein

GENE ID SPECIES
9047 Homo sapiens
100687395 Canis lupus familiaris
530059 Bos taurus
310688 Rattus norvegicus
27371 Mus musculus
Selected quality suppliers for anti-SH2 Domain Protein 2A (SH2D2A) Antibodies
Did you look for something else?