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anti-SHANK-Associated RH Domain Interacting Protein (SHARPIN) Antibodies

directly interacts with the ankyrin repeats of Shank; may be involved in regulating the function of Shank. Additionally we are shipping and SHARPIN Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SHARPIN 106025 Q91WA6
SHARPIN 81858 Q9H0F6
SHARPIN 81859 Q9EQL9
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Top anti-SHARPIN Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SHARPIN Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Hela cell lysate WB Suggested Anti-SHARPIN  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Hela cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB SHARPIN Antibody (Center)  western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the SHARPIN antibody detected the SHARPIN protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.89 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   200 μL Log in to see 11 to 16 Days
$532.71
Details
Human Rabbit FITC ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details
Human Rabbit PE ELISA, WB   200 μL Log in to see 16 Days
$710.29
Details

SHARPIN Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Human ,
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Rat (Rattus) ,


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More Antibodies against SHARPIN Interaction Partners

Mouse (Murine) SHANK-Associated RH Domain Interacting Protein (SHARPIN) interaction partners

  1. Study identifies a role for SHARPIN in TCR signaling whereby it maintains immunological homeostasis and tolerance by regulating Treg cells.

  2. severity of the esophagitis was not affected by crossing SHARPIN-deficient mice with lymphocyte-deficient Rag1 (show RAG1 Antibodies) null mice

  3. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.

  4. Data indicate that genetic ablation of caspase-1 (show CASP1 Antibodies) and -11 from cpdm mice significantly reduced skin inflammation in sharpin-deficient mice.

  5. Our results suggest that SHARPIN plays a significant role in skeletal homeostasis and that this role is strongly regulated through TNF (show TNF Antibodies) pathways.

  6. Sharpin deficiency sensitized primary murine keratinocytes, human keratinocytes, and mouse embryonic fibroblasts to TNF (show TNF Antibodies)-induced apoptosis.

  7. Tnfr1 (show TNFRSF1A Antibodies), but not Tnfr2 (show TNFRSF1B Antibodies), deficiency suppresses inflammation in sharpin deficient mice.

  8. SHARPIN is required for optimal NLRP3 (show NLRP3 Antibodies) inflammasome activation.

  9. Sharpin deficiency results in chronic proliferative dermatitis/ autoinflammatory disease in the absence of B and T lymphocytes and IL4 (show IL4 Antibodies)/IL13 (show IL13 Antibodies) signaling.

  10. SHARPIN controls lymphocyte migration by endogenously maintaining LFA-1 (show ITGAL Antibodies) inactive to allow adjustable detachment of the uropods in polarized cells.

Human SHANK-Associated RH Domain Interacting Protein (SHARPIN) interaction partners

  1. Data show that SHANK-associated RH domain interacting protein (SHARPIN) gene expression in breast cancer patients predicts clinical outcomes.

  2. the roles of SHARPIN in inhibiting integrin activity and supporting linear ubiquitination are (molecularly) distinct.

  3. progesterone significantly reduced SIPL1 mRNA and protein expression in MCF7 cells. As progesterone enhances breast cancer tumorigenesis in context dependent manner, inhibition of SIPL1 expression may contribute to progesterone's non-tumorigenic function

  4. SIPL1 binds PTEN (show PTEN Antibodies) and enhances PTEN (show PTEN Antibodies) polyubiquitination.

  5. Sharpin deficiency sensitized primary murine keratinocytes, human keratinocytes, and mouse embryonic fibroblasts to TNF (show TNF Antibodies)-induced apoptosis.

  6. SIPL1 promotes AKT (show AKT1 Antibodies) activation by decreasing the amount of PTEN (show PTEN Antibodies) protein in CHO (show COL11A1 Antibodies)-K1 cells.

  7. SHARPIN controls lymphocyte migration by endogenously maintaining LFA-1 (show ITGAL Antibodies) inactive to allow adjustable detachment of the uropods in polarized cells.

  8. crystals of SHARPIN belonged to the primitive tetragonal space group P4(3)2(1)2, with unit-cell parameters a = b = 61.55, c = 222.81 A

  9. the crystal structure of the N-terminal portion of SHARPIN, which adopts the highly conserved pleckstrin (show PLEK Antibodies) homology superfold that is often used as a scaffold to create protein interaction modules

  10. SHARPIN inhibits the critical switching of beta1-integrins from inactive to active conformations.

SHARPIN Antigen Profile

Protein Summary

directly interacts with the ankyrin repeats of Shank; may be involved in regulating the function of Shank

Gene names and symbols associated with SHARPIN

  • SHANK-associated RH domain interacting protein (Sharpin) antibody
  • SHANK-associated RH domain interactor (SHARPIN) antibody
  • SHANK-associated RH domain interactor (Sharpin) antibody
  • 0610041B22Rik antibody
  • AW121341 antibody
  • Conneck1 antibody
  • cpdm antibody
  • RBCKL1 antibody
  • SIPL1 antibody

Protein level used designations for SHARPIN

mSIPL1 , protein kinase C-interacting protein RBCC like 1 , shank-associated RH domain-interacting protein , shank-interacting protein-like 1 , sharpin , hSIPL1 , SHANK-associated RH domain interacting protein , shank-interacting protein

GENE ID SPECIES
106025 Mus musculus
81858 Homo sapiens
81859 Rattus norvegicus
512499 Bos taurus
475122 Canis lupus familiaris
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