SHANK-Associated RH Domain Interacting Protein (SHARPIN) ELISA Kits

directly interacts with the ankyrin repeats of Shank; may be involved in regulating the function of Shank. Additionally we are shipping SHARPIN Antibodies (52) and and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
SHARPIN 106025 Q91WA6
SHARPIN 81858 Q9H0F6
SHARPIN 81859 Q9EQL9
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Top SHARPIN ELISA Kits at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human
96 Tests Log in to see 15 to 18 Days
$875.60
Details
Mouse
96 Tests Log in to see 15 to 18 Days
$875.60
Details
Rat
96 Tests Log in to see 15 to 18 Days
$875.60
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Cow
96 Tests Log in to see 15 to 18 Days
$1,029.60
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More ELISA Kits for SHARPIN Interaction Partners

Mouse (Murine) SHANK-Associated RH Domain Interacting Protein (SHARPIN) interaction partners

  1. LUBAC components control TLR3 (show TLR3 ELISA Kits)-mediated innate immunity, thereby preventing development of immunodeficiency and autoinflammation.

  2. Suppression of SHARPIN impaired cell proliferation, angiogenesis, and invasion and reduced levels of MMP-9 in P (show EPHB2 ELISA Kits)rost (show AKT1 ELISA Kits)ate cancer cells and reduced the size of Metastatic Lung tumors induced by these cells in mice.

  3. Together, these data imply that SHARPIN regulates the normal invasive mammary gland branching morphogenesis in an epithelial cell extrinsic manner by controlling the organisation of the stromal extracellular matrix.

  4. Study found that the NZF domain of SHARPIN, but not that of HOIL-1L (show RBCK1 ELISA Kits), is critical for effective protection from programmed cell death by enhancing the recruitment of the linear ubiquitin chain assembly complex to the activated TNFR (show TNFRSF1A ELISA Kits) complex. The binding activity to K63-linked ubiquitin chains that the NZF domain of SHARPIN, but not that of HOIL-1L (show RBCK1 ELISA Kits), possesses appears to be involved in the recruitment.

  5. this study reveals a critical function of SHARPIN in TCR-induced NF-kappaB (show NFKB1 ELISA Kits) and JNK (show MAPK8 ELISA Kits) signalling and thymic Treg cell generation

  6. SHARPIN-deficient mice develop a chronic proliferative dermatitis presenting angiogenesis and lymphatic dilatation.

  7. Study identifies a role for SHARPIN in TCR signaling whereby it maintains immunological homeostasis and tolerance by regulating Treg cells.

  8. severity of the esophagitis was not affected by crossing SHARPIN-deficient mice with lymphocyte-deficient Rag1 (show RAG1 ELISA Kits) null mice

  9. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.

  10. Data indicate that genetic ablation of caspase-1 (show CASP1 ELISA Kits) and -11 from cpdm mice significantly reduced skin inflammation in sharpin-deficient mice.

Human SHANK-Associated RH Domain Interacting Protein (SHARPIN) interaction partners

  1. LUBAC components control TLR3 (show TLR3 ELISA Kits)-mediated innate immunity, thereby preventing development of immunodeficiency and autoinflammation.

  2. Overexpression of SHARPIN in Prostate cancer cells promoted cell growth and reduced apoptosis through NF-kB/ERK (show EPHB2 ELISA Kits)/Akt (show AKT1 ELISA Kits) pathway and apoptosis-associated proteins. SHARPIN enhances the metastasis of prostate cancer and impair patient survivals.

  3. Our study firstly identifies the role of SHARPIN in promoting wild-type P53 (show TP53 ELISA Kits) degradation and correlates with poor prognosis in P53 (show TP53 ELISA Kits) wild-type breast cancer.

  4. Data show that SHANK-associated RH domain interacting protein (SHARPIN) gene expression in breast cancer patients predicts clinical outcomes.

  5. the roles of SHARPIN in inhibiting integrin activity and supporting linear ubiquitination are (molecularly) distinct.

  6. progesterone significantly reduced SIPL1 mRNA and protein expression in MCF7 cells. As progesterone enhances breast cancer tumorigenesis in context dependent manner, inhibition of SIPL1 expression may contribute to progesterone's non-tumorigenic function

  7. SIPL1 binds PTEN and enhances PTEN polyubiquitination.

  8. Sharpin deficiency sensitized primary murine keratinocytes, human keratinocytes, and mouse embryonic fibroblasts to TNF (show TNF ELISA Kits)-induced apoptosis.

  9. SIPL1 promotes AKT (show AKT1 ELISA Kits) activation by decreasing the amount of PTEN protein in CHO (show COL11A1 ELISA Kits)-K1 cells.

  10. SHARPIN controls lymphocyte migration by endogenously maintaining LFA-1 (show ITGAL ELISA Kits) inactive to allow adjustable detachment of the uropods in polarized cells.

SHARPIN Antigen Profile

Antigen Summary

directly interacts with the ankyrin repeats of Shank; may be involved in regulating the function of Shank

Gene names and symbols associated with SHARPIN

  • SHANK-associated RH domain interacting protein (Sharpin) antibody
  • SHANK-associated RH domain interactor (SHARPIN) antibody
  • SHANK-associated RH domain interactor (Sharpin) antibody
  • 0610041B22Rik antibody
  • AW121341 antibody
  • Conneck1 antibody
  • cpdm antibody
  • RBCKL1 antibody
  • SIPL1 antibody

Protein level used designations for SHARPIN

mSIPL1 , protein kinase C-interacting protein RBCC like 1 , shank-associated RH domain-interacting protein , shank-interacting protein-like 1 , sharpin , hSIPL1 , SHANK-associated RH domain interacting protein , shank-interacting protein

GENE ID SPECIES
106025 Mus musculus
81858 Homo sapiens
81859 Rattus norvegicus
512499 Bos taurus
475122 Canis lupus familiaris
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