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anti-SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) Antibodies

Acts as a transcriptional repressor. Additionally we are shipping SIN3 Transcription Regulator Homolog B (Yeast) Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIN3B 23309 O75182
SIN3B 683381  
SIN3B 20467 Q62141
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Top anti-SIN3 Transcription Regulator Homolog B (Yeast) Antibodies at antibodies-online.com

Showing 10 out of 51 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SIN3B Antibody Titration: 0.2-1 ug/mlPositive Control: Human brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SIN3B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HCT15 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SIN3B Antibody Titration: 2.5ug/mlELISA Titer: 1:1562500Positive Control: SP2/0 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Mouse Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Mouse Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IC, IF, WB Immunofluorescent analysis of SIN3B staining in HCT116 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Western blot analysis of SIN3B expression in HCT116 (A) whole cell lysates. 200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

SIN3B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SIN3 Transcription Regulator Homolog B (Yeast) Antibodies

  1. Mouse (Murine) Polyclonal SIN3B Primary Antibody for WB - ABIN2779895 : Nomura, Uda-Tochio, Murai, Mori, Nishimura: The neural repressor NRSF/REST binds the PAH1 domain of the Sin3 corepressor by using its distinct short hydrophobic helix. in Journal of molecular biology 2005 (PubMed)

  2. Cow (Bovine) Polyclonal SIN3B Primary Antibody for WB - ABIN2784243 : Dhanda, Lindberg, Olsson: The human SIN3B corepressor forms a nucleolar complex with leukemia-associated ETO homologues. in BMC molecular biology 2008 (PubMed)

More Antibodies against SIN3 Transcription Regulator Homolog B (Yeast) Interaction Partners

Human SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) interaction partners

  1. these results suggest that stress-induced Sin3B activation is p53 (show TP53 Antibodies)-dependent and is essential for p53 (show TP53 Antibodies)-mediated repression of its selective target genes.

  2. The study suggests that the difference in the conformation of native state structure or structural flexibility of the paired amphi pathic helices (PAH) domains of Sin3B might be responsible for interacting with specific binding partners.

  3. A conserved Myc (show MYC Antibodies) region (amino acids 186-203) is required for the interaction with Sin3 proteins. Histone deacetylase 1 (show HDAC1 Antibodies) is recruited to Myc (show MYC Antibodies)-Sin3b complexes, and its deacetylase activity is required for the effects of Sin3b on Myc (show MYC Antibodies).

  4. this study highlights an essential role for Sin3B in IFN-c induced COL1A2 (show COL1A2 Antibodies) repression in smooth muscle cells.

  5. Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression

  6. the essential role of Sin3B as an important associate of p53 (show TP53 Antibodies) in mediating the cellular responses to stress and in the transcriptional repression of genes

  7. identification of a mammalian complex containing the corepressor Sin3B, the histone deacetylase HDAC1 (show HDAC1 Antibodies), Mrg15 (show MORF4L1 Antibodies), and the PHD (show PDC Antibodies) finger-containing Pf1 (show PHF12 Antibodies)

  8. disruption of the function of a specific Sin3A (show SIN3A Antibodies)/B domain leads to epigenetic reprogramming and derepression of specific subsets of genes in breast cancer cells

  9. SMAR1 (show BANP Antibodies) regulates cyclin D1 (show CCND1 Antibodies) by modification of chromatin through the SIN3/histone deacetylase 1 (show HDAC1 Antibodies) complex

  10. The interaction between SIN3B and ETO (show RUNX1T1 Antibodies) required an intact amino-terminus of ETO (show RUNX1T1 Antibodies) and the NHR2 domain.

Mouse (Murine) SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) interaction partners

  1. Sin3B is required for the senescent phenotype and elevated levels of reactive oxygen species elicited upon Bmi-1 (show BMI1 Antibodies) depletion.

  2. Senescence-associated SIN3B promotes inflammation and pancreatic cancer progression

  3. interaction with Sin3B influences Na(v)-channel trafficking or stability in the membrane.

  4. Sin3 has an important role in the regulation of cell cycle kinetics of the myogenic progenitor cell population

  5. Results describe a novel transcriptional role for Sin3A and Sin3B proteins associated with maintenance of differentiated muscle cells.

  6. RNF220 was identified as a novel ubiquitin ligase for Sin3B.

  7. ESET (show SETDB1 Antibodies) histone methyltransferase can form a large, multi-protein complex(es) with mSin3A/B co-repressors and HDAC1 (show HDAC1 Antibodies)/2 that participates in multiple pathways of transcriptional repression.

  8. When tethered in cis (show CISH Antibodies) to DNA, the transcriptional corepressor mSin3B inhibits polyomavirus (Py) ori-dependent DNA replication in vivo.

  9. Phe-7 is the critical determinant and provides the molecular specificity for the association between Sin3 and Mad in regulating cell growth and differentiation.

  10. The Myt1 (show MYT1 Antibodies) family of zinc finger proteins, when bound to a neural promoter, can recruit Sin3B. Depending on the relative availability of Sin3B isoforms, the Myt1 (show MYT1 Antibodies) gene family may favor the silencing of genes during neural development.

SIN3 Transcription Regulator Homolog B (Yeast) (SIN3B) Antigen Profile

Protein Summary

Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3B to DNA. Also forms a complex with FOXK1 which represses transcription (By similarity).

Gene names and symbols associated with SIN3B

  • SIN3 homolog B, transcription regulator (yeast) (sin3b) antibody
  • SIN3 transcription regulator family member B (SIN3B) antibody
  • SIN3 transcription regulator homolog B (sin3b) antibody
  • SIN3 transcription regulator homolog B (yeast) (SIN3B) antibody
  • SIN3 transcription regulator homolog B (yeast) (Sin3b) antibody
  • transcriptional regulator, SIN3B (yeast) (Sin3b) antibody
  • 2810430C10Rik antibody
  • fj63d08 antibody
  • si:dkey-6n6.6 antibody
  • wu:fj63d08 antibody

Protein level used designations for SIN3B

paired amphipathic helix protein Sin3b , SIN3 homolog B, transcription regulator , SIN3 homolog B, transcriptional regulator , SIN3 transcription regulator homolog B , histone deacetylase complex subunit Sin3b , transcriptional corepressor Sin3b , transcriptional regulator, SIN3B , transcriptional regulator, SIN3 yeast homolog B

GENE ID SPECIES
560837 Danio rerio
23309 Homo sapiens
100036844 Xenopus laevis
520505 Bos taurus
683381 Rattus norvegicus
420140 Gallus gallus
610198 Canis lupus familiaris
20467 Mus musculus
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