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SIVA1, Apoptosis-Inducing Factor Proteins (SIVA1)

SIVA1 encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. Additionally we are shipping SIVA1 Antibodies (39) and SIVA1 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SIVA1 10572 O15304
SIVA1 30954 O54926
SIVA1 362791  
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Top SIVA1 Proteins at antibodies-online.com

Showing 9 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
Yeast Human His tag 50 μg Log in to see 31 to 36 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$792.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,414.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SIVA1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine)

Rat (Rattus)

More Proteins for SIVA1, Apoptosis-Inducing Factor (SIVA1) Interaction Partners

Human SIVA1, Apoptosis-Inducing Factor (SIVA1) interaction partners

  1. Loss of SIVA1 expression is associated with nasopharyngeal carcinoma.

  2. These findings collectively reveal a novel role for the p53 (show TP53 Proteins) target gene SIVA both in regulating metabolism and in enabling tumorigenesis, independently of p53 (show TP53 Proteins).

  3. Functional test demonstrated that Siva1 significantly inhibited the invasion and migration of HCT116 cells.

  4. electrical stimulation -inducible SIVA1 modulates p53 (show TP53 Proteins) activities in proliferating keratinocytes, and exogenous electrical stimulation affects p53 (show TP53 Proteins)/HDM2/SIVA1 axis leading to increased proliferation during re-epithelialization

  5. SIVA1 interacts with RAD18 (show RAD18 Proteins) and serves as a molecular bridge between RAD18 (show RAD18 Proteins) and PCNA (show PCNA Proteins), thus targeting the E3 ligase activity of RAD18 (show RAD18 Proteins) onto PCNA (show PCNA Proteins).

  6. Siva1 promotes the ubiquitination and degradation of ARF, which in turn affects the stability of p53 (show TP53 Proteins).

  7. Upon stimulation of thromboxane A2, degradation of Siva1 is impeded, resulting in an accumulation of the protein, which translocates from the nucleus to the cytosol.

  8. negative regulator of IL-2 gene expression in Treg cells

  9. Data show that low levels of Siva1 and Ser16-phosphorylated stathmin (show STMN1 Proteins) correlate with high metastatic states of breast cancer cells.

  10. These findings suggest that the caspase (show CASP3 Proteins)-dependent pathway for induction of apoptosis is involved in Siva-1-mediated influenza A virus replication.

Mouse (Murine) SIVA1, Apoptosis-Inducing Factor (SIVA1) interaction partners

  1. These findings collectively reveal a novel role for the p53 (show TP53 Proteins) target gene SIVA both in regulating metabolism and in enabling tumorigenesis, independently of p53 (show TP53 Proteins).

  2. Data indicate that p53 (show TP53 Proteins) target Siva is pivotal in regulating apoptosis in the pathology of renal ischemia reperfusion injury.

  3. SIVA is a direct transcriptional target for the tumor suppressors p53 (show TP53 Proteins) and E2F1 (show E2F1 Proteins)

  4. Siva's expression pattern suggests that it plays an instructive role in apoptosis, and accordingly, we demonstrate that Siva is essential for p53 (show TP53 Proteins)-dependent apoptosis in cerebellar granule neurons.

  5. lysophosphatidic acid 2 (show PTOV1 Proteins) receptor mediates down-regulation of Siva-1 to promote cell survival

  6. Data show that SLIMMER (show FHL1 Proteins) delayed Siva-1-dependent apoptosis in C2C12 myoblasts.

SIVA1 Protein Profile

Protein Summary

This gene encodes a protein with an important role in the apoptotic (programmed cell death) pathway induced by the CD27 antigen, a member of the tumor necrosis factor receptor (TFNR) superfamily. The CD27 antigen cytoplasmic tail binds to the N-terminus of this protein. Two alternatively spliced transcript variants encoding distinct proteins have been described.

Gene names and symbols associated with SIVA1

  • SIVA1, apoptosis-inducing factor (SIVA1)
  • SIVA1, apoptosis-inducing factor (Siva1)
  • CD27bp protein
  • Siva protein
  • Siva-1 protein
  • Siva-2 protein

Protein level used designations for SIVA1

CD27-binding (Siva) protein , apoptosis regulatory protein Siva , CD27-binding protein , Cd27 binding protein , CD27BP

GENE ID SPECIES
10572 Homo sapiens
30954 Mus musculus
362791 Rattus norvegicus
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