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The protein encoded by SIX1 is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. Additionally we are shipping SIX Homeobox 1 Antibodies (33) and SIX Homeobox 1 Proteins (6) and many more products for this protein.
Our findings imply that SIX1 may play a role as an important regulator to orchestrate the dynamic of uterine endometrium in response to estrogen level during the estrous cycle.
Activation of Six1 Expression in Vertebrate Sensory Neurons.
Six1 knockdown caused a fast-to-slow shift in myosin heavy chain isoform
Results suggest that the increase of SIX1 expression could promote tumorigenesis, progression and invasive growth of cervical cancer by promoting DNA replication.
Fast myosin heavy chain (show MYH8 ELISA Kits) (MYH (show MUTYH ELISA Kits)) genes and linc-MYH (show MUTYH ELISA Kits) share a common enhancer, located in the fast MYH (show MUTYH ELISA Kits) gene locus and regulated by Six1 homeoproteins
The results indicated the critical role of Six1 in transition of Rohon-Beard cells to dorsal root ganglia (DRG) neurons during Xenopus development and establishment of exclusive DRG system of mice.
Six1 is required for the proper chromatin structure at the Core Enhancer Region, as well as for MyoD (show MYOD1 ELISA Kits) binding at its own enhancer.
Results indicated that sine oculis homeobox (show PRRX1 ELISA Kits) 1 (Six1) overexpression could significantly promote the expression of fast-type muscle genes Atp2a1 (show ATP2A1 ELISA Kits), Srl (show SRL ELISA Kits), and Mylpf (show MYLPF ELISA Kits).
These findings uncover novel functions for Six1-Eya1 (show EYA1 ELISA Kits)-SHH (show SHH ELISA Kits) pathway during the saccular phase of lung morphogenesis.
the transcription factors Six1 and Six4 (show SIX4 ELISA Kits) are required for male gonadal differentiation.
Mutations of SIX1 gene underlie Wilms tumor recurrences.
Six1 signaling has a role in paclitaxel-dependent apoptosis in MCF-7 cell line
Six1 mutations/gene deletion are unlikely to be a major cause of nonsyndromic CAKUT.
Data show that the protein domain interfaces may represent therapeutic targets in homeo domain protein SIX1-positive Hodgkin lymphoma (HL) subsets.
Data show that both Ezrin (show EZR ELISA Kits) and SIX1 proteins are highly expressed in alpha fetoprotein (show AFP ELISA Kits)-negative hepatocellular carcinoma (HCC (show FAM126A ELISA Kits)) and significantly related with the TNM (show ODZ1 ELISA Kits) stage.
Single nucleotide polymorphism in SIX1 gene is associated with primary open angle glaucoma.
High expression of SIX1 is an independent prognostic marker in colorectal cancer.
Three causative genes for BOR (show EYA1 ELISA Kits) syndrome have been reported thus far: EYA1 (show EYA1 ELISA Kits), SIX1, and SIX5, but the causative genes for approximately half of all BOR (show EYA1 ELISA Kits) patients remain unknown.[review]
SIX1 and EYA are often co-overexpressed in tumors, and the SIX1-EYA2 (show EYA2 ELISA Kits) interaction has been shown to be critical for metastasis in a breast cancer model.
Six1 plays an important role in the TIC (show ARNTL ELISA Kits) population in luminal breast cancers and induces a TIC (show ARNTL ELISA Kits) phenotype by enhancing both TGF-beta (show TGFB1 ELISA Kits) and ERK (show EPHB2 ELISA Kits) signaling.
The HD domain is important for the nuclear localization of porcine Six1 protein.
Microarray identification of novel genes downstream of Six1, a critical factor in cranial placode, somite, and kidney development.
Eya1 (show EYA1 ELISA Kits) and Six1 are required for both the regulation of placodal neuronal progenitor proliferation, through their effects on SoxB1 expression, and subsequent neuronal differentiation.
The protein encoded by this gene is a homeobox protein that is similar to the Drosophila 'sine oculis' gene product. This gene is found in a cluster of related genes on chromosome 14 and is thought to be involved in limb development. Defects in this gene are a cause of autosomal dominant deafness type 23 (DFNA23) and branchiootic syndrome type 3 (BOS3).
homeobox protein SIX1
, sine oculis homeobox homolog 1
, sine oculis-related homeobox 1 homolog
, Sine oculis homeobox homolog 1
, homeobox protein six1