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anti-SIX Homeobox 2 (SIX2) Antibodies

SIX2 is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. Additionally we are shipping SIX Homeobox 2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SIX2 20472 Q62232
SIX2 10736 Q9NPC8
SIX2 366542  
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Top anti-SIX Homeobox 2 Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB SIX2 Antibody (Center)  western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the SIX2 antibody detected the SIX2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated RNAi, ELISA, WB Western Blot analysis of SIX2 expression in transfected 293T cell line by SIX2 monoclonal antibody (M01), clone 3D7.Lane 1: SIX2 transfected lysate(32.3 KDa).Lane 2: Non-transfected lysate. Western blot analysis of SIX2 over-expressed 293 cell line, cotransfected with SIX2 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with SIX2 monoclonal antibody (M01), clone 3D7. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Mouse Un-conjugated WB Western blot analysis of SIX2 over-expressed 293 cell line, cotransfected with SIX2 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of SIX2 expression in transfected 293T cell line by SIX2 monoclonal antibody (M01), clone 3D7. Lane 1: SIX2 transfected lysate(32.3 KDa). Lane 2: Non-transfected lysate. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 14 Days
$201.19
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (57.75 KDa) . 100 μg Log in to see 9 Days
$430.00
Details

SIX2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SIX Homeobox 2 Antibodies

  1. Human Monoclonal SIX2 Primary Antibody for RNAi, ELISA - ABIN564682 : Lee, Kim, Ryu, Lee, Yang, Jeong, Kim, Lee, Kim, Hajjar, Park: Transcription coactivator Eya2 is a critical regulator of physiological hypertrophy. in Journal of molecular and cellular cardiology 2012 (PubMed)
    Show all 5 references for ABIN564682

  2. Chicken Polyclonal SIX2 Primary Antibody for WB - ABIN2781019 : Weber, Taylor, Winyard, Baker, Sullivan-Brown, Schild, Knüppel, Zurowska, Caldas-Alfonso, Litwin, Emre, Ghiggeri, Bakkaloglu, Mehls, Antignac, Network, Schaefer, Burdine: SIX2 and BMP4 mutations associate with anomalous kidney development. in Journal of the American Society of Nephrology : JASN 2008 (PubMed)

More Antibodies against SIX Homeobox 2 Interaction Partners

Zebrafish SIX Homeobox 2 (SIX2) interaction partners

  1. Balancing cell numbers during organogenesis: Six1a differentially affects neurons and sensory hair cells in the inner ear

  2. Six1a plays an essential role at the onset of fast muscle differentiation.

  3. six1a and pax3 (show PAX3 Antibodies) do not function in the same regulatory network. We proposed four putative regulatory pathways to understand how six1a distinctly interacts with either myf5 (show MYF5 Antibodies) or myod (show MYOD1 Antibodies) during zebrafish craniofacial muscle development.

Mouse (Murine) SIX Homeobox 2 (SIX2) interaction partners

  1. Mechanistically, LIF (show LIF Antibodies) activates STAT (show STAT1 Antibodies), which binds to a Stat (show STAT1 Antibodies) consensus sequence in the Six2 proximal promoter and sustains SIX2 levels.

  2. Dicer (show DICER1 Antibodies) ablation in the early metanephric mesenchyme results in severe renal dysgenesis despite normal initial specification of nephron progenitors and ureteric bud outgrowth.

  3. miR181c downregulates the expression of Six2, restrain the proliferation and promote the apoptosis that even makes the nephron progenitor phenotype lose MM cells, suggesting a potential role of miR181c during the kidney development.

  4. results reveal a functional link between Eya1 (show EYA1 Antibodies), Six2, and Myc (show MYC Antibodies) in driving the expansion and maintenance of the multipotent progenitors during nephrogenesis

  5. Our findings establish Six2 as a regulator of metastasis in human breast cancers and demonstrate an epigenetic function for SIX family transcription factors in metastatic progression through the regulation of E-cadherin (show CDH1 Antibodies).

  6. These results implied that inhibition of Nf1 (show NF1 Antibodies) may delay metanephros development via down-regulation of Six2.

  7. Osr1 (show OSR1 Antibodies) plays crucial roles in Six2-dependent maintenance of nephron progenitors during mammalian nephrogenesis.

  8. this study concluded that by targeting the transcription factor gene Six2, miR (show MLXIP Antibodies)-181b inhibits the proliferation of metanephric mesenchymal cells in vitro and might play an important role in the formation of nephrons.

  9. Six1 (show SIX1 Antibodies) and Six2 are complementarily but asymmetrically expressed in the peri (show POSTN Antibodies)-cloacal mesenchymal progenitors and are critical for correct genitor-urinary and digestive organs body patterning.

  10. Wnt (show WNT2 Antibodies) and BMP signaling cooperate with Hox (show MSH2 Antibodies) in the control of Six2 expression in limb tendon precursor.

Xenopus laevis SIX Homeobox 2 (SIX2) interaction partners

  1. Data show that three of the eight conserved noncoding sequences (CNSs) located within a 317-kb segment of the Six2 genomic locus were nephric enhancers.

Human SIX Homeobox 2 (SIX2) interaction partners

  1. SIX2 deletion is associated with frontonasal dysplasia syndrome.

  2. SIX2 overexpression and concomitantly decreased promoter methylation.

  3. in tumors with DGCR8 (show DGCR8 Antibodies) E518K and DROSHA (show DROSHA Antibodies) exon 29 (miRNAPG-HS) mutations ... greater prevalence of tumors with blastemal predominant histology in patients with miRNAPG-HS and/or SIX1 (show SIX1 Antibodies)/2 Q177R mutations

  4. Recurrent mutations included a hotspot mutation (Q177R) in the homeo-domain of SIX1 (show SIX1 Antibodies) and SIX2 in tumors with high proliferative potential (18.1% of blastemal cases); mutations in the DROSHA (show DROSHA Antibodies)/DGCR8 (show DGCR8 Antibodies) microprocessor genes

  5. Nuclear protein (show RDBP Antibodies) & mRNA expression of SIX2 were similar across all stages of disease, in favorable or unfavorable histology & in treatment failure or success. It is not found in normal kidney.

  6. Lack of mutations in the coding regions of SIX2 among the sporadic microtia patients

SIX Homeobox 2 (SIX2) Antigen Profile

Protein Summary

This gene is a member of the vertebrate gene family which encode proteins homologous to the Drosophila 'sine oculis' homeobox protein. The encoded protein is a transcription factor which, like other members of this gene family, may be involved in limb or eye development.

Gene names and symbols associated with anti-SIX Homeobox 2 (SIX2) Antibodies

  • sine oculis homeobox homolog 1a (six1a) antibody
  • sine oculis-related homeobox 2 (Six2) antibody
  • SIX homeobox 2 (six2) antibody
  • SIX homeobox 2 (SIX2) antibody
  • SIX homeobox 2 (Six2) antibody
  • six1b antibody
  • six2 antibody
  • six2-A antibody
  • zgc:92332 antibody

Protein level used designations for anti-SIX Homeobox 2 (SIX2) Antibodies

homeobox protein six1a , homeobox protein six1b , homeodomain transcription factor Six1b , sine oculis homeobox homolog 1b , sine oculis homeobox homolog 2 , homeobox protein SIX2 , sine oculis-related homeobox 2 homolog , sine oculis-related homeobox 2

GENE ID SPECIES
494168 Danio rerio
20472 Mus musculus
373734 Xenopus laevis
724086 Gallus gallus
10736 Homo sapiens
481357 Canis lupus familiaris
539492 Bos taurus
366542 Rattus norvegicus
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