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SKI-Like Oncogene (SKIL) ELISA Kits

The protein encoded by SKIL is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). Additionally we are shipping SKI-Like Oncogene Antibodies (88) and SKI-Like Oncogene Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Mouse SKIL SKIL 20482 Q60665
SKIL 6498 P12757
Anti-Rat SKIL SKIL 114208  
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Top SKI-Like Oncogene ELISA Kits at antibodies-online.com

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Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human < 0.055 ng/mL 31.25-2000 pg/mL 96 Tests Log in to see 9 to 11 Days
$810.53
Details

More ELISA Kits for SKI-Like Oncogene Interaction Partners

Mouse (Murine) SKI-Like Oncogene (SKIL) interaction partners

  1. Loss of SnoN is associated with partial embryonic lethality, mostly due to defects in angiogenesis in both the yolk sac (show ADCY10 ELISA Kits) and embryo body

  2. SnoN mediates a negative feedback mechanism evoked by TGF-beta to inhibit BMP signaling and, subsequently, hypertrophic maturation of chondrocytes.

  3. SnoN, a negative regulator of TGF-beta (show TGFB1 ELISA Kits) signaling, coordinates TGF-beta (show TGFB1 ELISA Kits) and prolactin (show PRL ELISA Kits) signaling to control alveologenesis and lactogenesis.

  4. mRNA for positive regulators of Fshb (show FSHB ELISA Kits) expression, such as Fos and Jun (show JUN ELISA Kits), were up-regulated at slower pulse frequencies than a number of potential negative regulators, such as the corepressors Skil, Crem (show CREM ELISA Kits), and Tgif1 (show TGIF1 ELISA Kits).

  5. The endogenous SnoN plays a role in regulating ADAM12 (show ADAM12 ELISA Kits) expression in response to TGFbeta1 (show TGFB1 ELISA Kits).

  6. The authors conclude that somatic and germ cells at all differentiation stages are actively transducing TGFbeta (show TGFB1 ELISA Kits) superfamily signals but that responses to these ligands may be selectively modulated by SnoN2.

  7. Sno (show SBNO2 ELISA Kits) is a significant negative regulator of antiproliferative TGF-beta (show TGFB1 ELISA Kits) signaling in both T cells and other cell types in vivo

  8. SnoN is directly regulated by sumoylation leading to the enhancement of the ability of SnoN to repress transcription in a promoter-specific manner

  9. SnoN plays both pro-tumorigenic and antitumorigenic roles at different stages of mammalian malignant progression

  10. Arkadia (show RNF111 ELISA Kits) induces degradation of SnoN and c-Ski (show SKI ELISA Kits) in addition to Smad7 (show SMAD7 ELISA Kits).

Human SKI-Like Oncogene (SKIL) interaction partners

  1. the findings of this study demonstrate that the downregulation of SnoN expression in hRPTECs under high-glucose conditions is mediated by the increased expression of Smurf2 through the TGF-b1/Smad (show SMAD1 ELISA Kits) signaling pathway.

  2. RNAi-mediated downregulation of SnoN effectively inhibited proliferation and enhanced apoptosis of pancreatic cells.

  3. SKIL knockdown led to growth arrest in PC-3 (show PCSK1 ELISA Kits) and LNCaP cell line models of prostate cancer, and its overexpression led to increased invasiveness in RWPE-1 cells.

  4. Whole exome sequencing of the blood of the patient and both parents revealed a de novo germline SKIL mutation in the child that was not present in either parent

  5. Data indicate that tripartite motif containing 33 (show TRIM33 ELISA Kits) protein TIF1gamma (show TRIM33 ELISA Kits) promotes sumoylation of SKI-like proto-oncogene (show RAB1A ELISA Kits) protein SnoN1 and regulates epithelial-mesenchymal transition (EMT (show ITK ELISA Kits)).

  6. The results indicate that protein ubiquitination promotes megakaryopoiesis via degrading SnoN, an inhibitor of CD61 (show ITGB3 ELISA Kits) expression, strengths the roles of ubiquitination in cellular differentiation.

  7. SnoNspecific siRNA is capable of effectively inhibiting the expression of SnoN in human HepG2 cells, and the downregulation of SnoN expression induces growth inhibition and apoptosis

  8. these studies identify TLOC1 (show TLOC1 ELISA Kits) and SKIL as driver genes at 3q26 and more broadly suggest that cooperating genes may be coamplified in other regions with somatic copy number gain.

  9. High SnoN expression is associated with metastasis in breast cancer.

  10. Phospholipid Scramblase 1 (show PLSCR1 ELISA Kits), an interferon (show IFNA ELISA Kits)-regulated gene located at 3q23, is regulated by SnoN/SkiL in ovarian cancer cells.

SKI-Like Oncogene (SKIL) Antigen Profile

Antigen Summary

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.

Gene names and symbols associated with SKI-Like Oncogene (SKIL) ELISA Kits

  • SKI-like oncogene (SKIL) antibody
  • SKI-like oncogene (skil) antibody
  • SKI-like (Skil) antibody
  • SKI-like oncogene (Skil) antibody
  • DKFZp459L122 antibody
  • SKIL antibody
  • Skir antibody
  • Sno antibody
  • SnoA antibody
  • SnoI antibody
  • SnoN antibody

Protein level used designations for SKI-Like Oncogene (SKIL) ELISA Kits

SKI-like oncogene , Ski-like protein , ski-like protein-like , ski-like protein , ski-related oncogene , ski/sno related , ski-related oncogene snoN , v-ski sarcoma viral oncogene homolog

GENE ID SPECIES
460844 Pan troglodytes
100010058 Monodelphis domestica
100057606 Equus caballus
100174070 Pongo abelii
100351337 Oryctolagus cuniculus
100395994 Callithrix jacchus
100474292 Ailuropoda melanoleuca
100492636 Xenopus (Silurana) tropicalis
100553902 Anolis carolinensis
100599983 Nomascus leucogenys
20482 Mus musculus
6498 Homo sapiens
488159 Canis lupus familiaris
527910 Bos taurus
114208 Rattus norvegicus
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