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Mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Additionally we are shipping SLAM Family Member 7 Proteins (17) and SLAM Family Member 7 Kits (4) and many more products for this protein.
Showing 10 out of 108 products:
Human Monoclonal SLAMF7 Primary Antibody for FACS, IP - ABIN2479975
Yamate, Ransom: Effects of altered gliogenesis on activity-dependent K+ accumulation in the developing rat optic nerve. in Brain research 1985
Show all 3 references for ABIN2479975
Human Monoclonal SLAMF7 Primary Antibody for FACS - ABIN2664564
Veillette: NK cell regulation by SLAM family receptors and SAP-related adapters. in Immunological reviews 2006
The SLAMF-AS2 (show ARSA Antibodies) isoforms are expressed the lowest levels among the three transcripts in both normal and infected mammary tissues.
Blimp-1 (show PRDM1 Antibodies) regulates the transcription of CS1 (show CSH1 Antibodies) gene in NK and B cell lines from multiple myeloma and diffuse large B cell lymphoma patients.
SLAMF7-triggered inhibition is mediated by a mechanism involving Src (show SRC Antibodies) kinases, CD45 (show PTPRC Antibodies), and SHIP-1 (show INPP5D Antibodies) that is defective in MM cells
Our data highlight the therapeutic potential of targeting CD319 in rheumatoid arthritis
SLAMF7 plays an inhibitory role in human monocytes to control proinflammatory immune responses.
These results suggest a role for CD319 and CD229 (show LY9 Antibodies) in the systemic lupus erythematosus disease process.
These data suggest an involvement of CRACC-mediated NK cell activation in periodontal tissue destruction and point to a plausible distinction in the pathobiology of aggressive and chronic periodontitis.
altered expression of splice variants of CS1 (show CSH1 Antibodies) and 2B4 (show CD244 Antibodies) that mediate differential signalling in PBMC from patients with SLE.
Data show that pair-wise ligations of 2B4 (show CD244 Antibodies) with DNAM-1 (show CD226 Antibodies) and/or NKG2D (show KLRK1 Antibodies) lead to increased effector functions of primary CD4 (show CD4 Antibodies)(+)CD28 (show CD28 Antibodies)(-) T cells to suboptimal levels of anti-CD3 (show CD3 Antibodies) stimulation.
CS1 (show CSH1 Antibodies)-L and CS1 (show CSH1 Antibodies)-S may differentially regulate human NK cell functions
blocking the engagement of 2B4, NTB-A and CRACC has no effect on the proliferation or development of the cytotoxic potential of NK cells but triggering by their physiological ligands on MHC class I-negative target cells induces potent NK cell cytotoxicity
CRACC-CRACC interaction between Kupffer and NK cells contributes to poly I:C/D-GalN (show GAL Antibodies) induced hepatitis.
2B4 (show CD244 Antibodies), NTB-A (show SLAMF6 Antibodies) and CRACC have roles in the regulation of Natural Killer cell function [review]
CRACC was a critical positive regulator of NK cell function mediated by EAT-2.
Mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion (By similarity).
SLAM family member 7
, SLAM family member 7 variant 1
, SLAM family member 7 variant 2
, 19A24 protein
, CD2 subset 1
, CD2-like receptor activating cytotoxic cells
, CD2-like receptor-activating cytotoxic cells
, membrane protein FOAP-12
, novel LY9 (lymphocyte antigen 9) like protein
, protein 19A
, leukocyte cell-surface antigen
, novel Ly9