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SLAM Family Member 7 Proteins (SLAMF7)

Mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. Additionally we are shipping SLAM Family Member 7 Antibodies (80) and SLAM Family Member 7 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat SLAMF7 SLAMF7 364049  
SLAMF7 57823 Q9NQ25
SLAMF7 75345 Q8BHK6
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Top SLAM Family Member 7 Proteins at antibodies-online.com

Showing 10 out of 18 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_HEK-293 Cells Human His tag 100 μg Log in to see 2 to 3 Days
$275.00
Details
HOST_HEK-293 Cells Human Fc Tag 100 μg Log in to see 11 Days
$275.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_HEK-293 Human His tag 50 μg Log in to see 2 to 3 Days
$630.00
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

SLAMF7 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , ,
, , , ,
Mouse (Murine) , ,
,

Top referenced SLAM Family Member 7 Proteins

  1. Human SLAMF7 Protein expressed in HEK-293 Cells - ABIN2181775 : Bouchon, Cella, Grierson, Cohen, Colonna: Activation of NK cell-mediated cytotoxicity by a SAP-independent receptor of the CD2 family. in Journal of immunology (Baltimore, Md. : 1950) 2001 (PubMed)
    Show all 2 references for ABIN2181775

  2. Human SLAMF7 Protein expressed in HEK-293 Cells - ABIN2181777 : Murphy, Hobby, Vilarino-Varela, Bishop, Iordanidou, Sutton, Norton: A novel immunoglobulin superfamily receptor (19A) related to CD2 is expressed on activated lymphocytes and promotes homotypic B-cell adhesion. in The Biochemical journal 2002 (PubMed)
    Show all 2 references for ABIN2181777

More Proteins for SLAM Family Member 7 (SLAMF7) Interaction Partners

Cow (Bovine) SLAM Family Member 7 (SLAMF7) interaction partners

  1. The SLAMF-AS2 (show ARSA Proteins) isoforms are expressed the lowest levels among the three transcripts in both normal and infected mammary tissues.

Human SLAM Family Member 7 (SLAMF7) interaction partners

  1. Blimp-1 (show PRDM1 Proteins) regulates the transcription of CS1 (show CSH1 Proteins) gene in NK and B cell lines from multiple myeloma and diffuse large B cell lymphoma patients.

  2. SLAMF7-triggered inhibition is mediated by a mechanism involving Src (show SRC Proteins) kinases, CD45 (show PTPRC Proteins), and SHIP-1 (show INPP5D Proteins) that is defective in MM cells

  3. Our data highlight the therapeutic potential of targeting CD319 in rheumatoid arthritis

  4. SLAMF7 plays an inhibitory role in human monocytes to control proinflammatory immune responses.

  5. These results suggest a role for CD319 and CD229 (show LY9 Proteins) in the systemic lupus erythematosus disease process.

  6. These data suggest an involvement of CRACC-mediated NK cell activation in periodontal tissue destruction and point to a plausible distinction in the pathobiology of aggressive and chronic periodontitis.

  7. altered expression of splice variants of CS1 (show CSH1 Proteins) and 2B4 (show CD244 Proteins) that mediate differential signalling in PBMC from patients with SLE.

  8. Data show that pair-wise ligations of 2B4 (show CD244 Proteins) with DNAM-1 (show CD226 Proteins) and/or NKG2D (show KLRK1 Proteins) lead to increased effector functions of primary CD4 (show CD4 Proteins)(+)CD28 (show CD28 Proteins)(-) T cells to suboptimal levels of anti-CD3 (show CD3 Proteins) stimulation.

  9. CS1 (show CSH1 Proteins)-L and CS1 (show CSH1 Proteins)-S may differentially regulate human NK cell functions

  10. blocking the engagement of 2B4, NTB-A and CRACC has no effect on the proliferation or development of the cytotoxic potential of NK cells but triggering by their physiological ligands on MHC class I-negative target cells induces potent NK cell cytotoxicity

Mouse (Murine) SLAM Family Member 7 (SLAMF7) interaction partners

  1. CRACC-CRACC interaction between Kupffer and NK cells contributes to poly I:C/D-GalN (show GAL Proteins) induced hepatitis.

  2. 2B4 (show CD244 Proteins), NTB-A (show SLAMF6 Proteins) and CRACC have roles in the regulation of Natural Killer cell function [review]

  3. CRACC was a critical positive regulator of NK cell function mediated by EAT-2.

SLAM Family Member 7 (SLAMF7) Protein Profile

Protein Summary

Mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion (By similarity).

Gene names and symbols associated with SLAM Family Member 7 Proteins (SLAMF7)

  • SLAM family member 7 (Slamf7)
  • SLAM family member 7 (SLAMF7)
  • SLAM family member 7 (slaf7)
  • 19A protein
  • 19A24 protein
  • 4930560D03Rik protein
  • CD319 protein
  • CRACC protein
  • CS1 protein
  • RGD1560190 protein
  • slaf7 protein
  • SLAMF7 protein

Protein level used designations for SLAM Family Member 7 Proteins (SLAMF7)

SLAM family member 7 , SLAM family member 7 variant 1 , SLAM family member 7 variant 2 , 19A24 protein , CD2 subset 1 , CD2-like receptor activating cytotoxic cells , CD2-like receptor-activating cytotoxic cells , membrane protein FOAP-12 , novel LY9 (lymphocyte antigen 9) like protein , protein 19A , leukocyte cell-surface antigen , novel Ly9

GENE ID SPECIES
364049 Rattus norvegicus
609992 Canis lupus familiaris
746961 Pan troglodytes
790164 Bos taurus
100196231 Salmo salar
57823 Homo sapiens
75345 Mus musculus
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