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Members of the SLITRK family, such as SLITRK6, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1\; MIM 603742). Additionally we are shipping SLITRK6 Antibodies (69) and many more products for this protein.
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Human SLITRK6 Protein expressed in HEK-293 Cells - ABIN2181779
Aruga, Yokota, Mikoshiba: Human SLITRK family genes: genomic organization and expression profiling in normal brain and brain tumor tissue. in Gene 2003
SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans.
SLITRK6 plays a crucial role in the development of normal hearing as well as vision in humans and in mice and that its disruption leads to a syndrome characterized by severe myopia and deafness.
the altered responses of Slitrk6-KO mice to the novel environment suggest a role of Slitrk6 in some cognitive functions.
Slitrk6 promotes innervation and survival of inner ear sensory neurons by regulating the expression of trophic and/or tropic factors including neurotrophins from sensory epithelia
Slitrk6 gene expression profile in the mouse embryo.
Members of the SLITRK family, such as SLITRK6, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1\; MIM 603742). Most SLITRKs, including SLITRK6, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1\; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003
slit and trk like 6
, SLIT and NTRK-like family, member 6
, SLIT and NTRK-like protein 6-like
, SLIT and NTRK-like protein 6
, slit and trk like gene 6
, neuronal transmembrane protein Slitrk6