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Members of the SLITRK family, such as SLITRK6, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1\; MIM 603742). Additionally we are shipping SLITRK6 Proteins (11) and many more products for this protein.
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Cow (Bovine) Polyclonal SLITRK6 Primary Antibody for WB - ABIN2784028
Mehrle, Rosenfelder, Schupp, del Val, Arlt, Hahne, Bechtel, Simpson, Hofmann, Hide, Glatting, Huber, Pepperkok, Poustka, Wiemann: The LIFEdb database in 2006. in Nucleic acids research 2005
SLITRK6 gene nonsense mutation is associated with progressive auditory neuropathy in humans.
SLITRK6 plays a crucial role in the development of normal hearing as well as vision in humans and in mice and that its disruption leads to a syndrome characterized by severe myopia and deafness.
the altered responses of Slitrk6-KO mice to the novel environment suggest a role of Slitrk6 in some cognitive functions.
Slitrk6 promotes innervation and survival of inner ear sensory neurons by regulating the expression of trophic and/or tropic factors including neurotrophins from sensory epithelia
Slitrk6 gene expression profile in the mouse embryo.
Members of the SLITRK family, such as SLITRK6, are integral membrane proteins with 2 N-terminal leucine-rich repeat (LRR) domains similar to those of SLIT proteins (see SLIT1\; MIM 603742). Most SLITRKs, including SLITRK6, also have C-terminal regions that share homology with neurotrophin receptors (see NTRK1\; MIM 191315). SLITRKs are expressed predominantly in neural tissues and have neurite-modulating activity (Aruga et al., 2003
slit and trk like 6
, SLIT and NTRK-like family, member 6
, SLIT and NTRK-like protein 6-like
, SLIT and NTRK-like protein 6
, slit and trk like gene 6
, neuronal transmembrane protein Slitrk6