anti-SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) Antibodies

GTPase-activating protein for RhoA and Cdc42 small GTPases. Additionally we are shipping SRGAP1 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SRGAP1 57522 Q7Z6B7
SRGAP1 117600 Q91Z69
SRGAP1 314903  
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Top anti-SRGAP1 Antibodies at antibodies-online.com

Showing 10 out of 54 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-Srgap1 AntibodyTitration: 1.0 µg/mL <br /> Positive Control: Mouse Brain 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IP, WB Western Blot and Immunoprecipitation: SRGAP1/ARHGAP13 Antibody [ABIN253121] - Detection of Human SRGAP1/ARHGAP13 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-SRGAP1/ARHGAP13 antibody ABIN253121 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. SRGAP1/ARHGAP13 was also immunoprecipitated by rabbit anti-SRGAP1/ARHGAP13 antibody ABIN253120, which recognizes an upstream epitope. Detection: Chemiluminescence ith exposure times of 30 seconds (A) and 1 second (B). 0.1 mL Log in to see 7 to 9 Days
$486.94
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SRGAP1 on formalin-fixed paraffin-embedded human salivary gland. [antibody concentration 3 ug/ml] Detection limit for recombinant GST tagged SRGAP1 is approximately 0.1ng/ml as a capture antibody. 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Mouse Un-conjugated IF, ELISA, WB SRGAP1 monoclonal antibody (M07), clone 5D10. Western Blot analysis of SRGAP1 expression in NIH/3T3. SRGAP1 monoclonal antibody (M07), clone 5D10. Western Blot analysis of SRGAP1 expression in IMR-32. 100 μg Log in to see 11 to 12 Days
$430.00
Details
Human Rabbit Un-conjugated WB SRGAP1 Antibody (Center)  western blot analysis in mouse stomach tissue lysates (35ug/lane).This demonstrates the SRGAP1 antibody detected the SRGAP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB 100 μg Log in to see 7 to 9 Days
$537.17
Details
Human Mouse Un-conjugated WB SRGAP1 monoclonal antibody (M03), clone 5D2 Western Blot analysis of SRGAP1 expression in IMR-32 on formalin-fixed paraffin-embedded human salivary gland (antibody concentration 3 µg/mL). 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IP Western Blot: SRGAP1/ARHGAP13 Antibody [ABIN253120] - Detection of Human SRGAP1/ARHGAP13 by Western Blot of Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SRGAP1/ARHGAP13 antibody ABIN253120 5Aused for IP at 3 mcg/mg lysate. SRGAP1/ARHGAP13 was also immunoprecipitated by rabbit anti-SRGAP1/ARHGAP13 antibody ABIN253121, which recognizes a downstream epitope. Detection: Chemiluminescence with an exposure time of 1 second. 100 μL Log in to see 7 to 9 Days
$486.94
Details
Human Rabbit Un-conjugated WB Western Blot showing Srgap1 antibody used at a concentration of 1.0 ug/ml against Mouse Brain Lysate 50 μg Log in to see 6 to 8 Days
$473.93
Details

SRGAP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-SRGAP1 Antibodies

  1. Human Polyclonal SRGAP1 Primary Antibody for IP, WB - ABIN253121 : Fan, Yang, Kumar, Tumelty, Pisarek-Horowitz, Rasouly, Sharma, Chan, Tyminski, Shamashkin, Belghasem, Henderson, Coyle, Salant, Berasi, Lu: SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. in JCI insight 2016 (PubMed)

  2. Human Monoclonal SRGAP1 Primary Antibody for IHC (p), ELISA - ABIN566130 : Dai, Ma, Chen, Mi, Fu, Cui, Jin: A link between the nuclear-localized srGAP3 and the SWI/SNF chromatin remodeler Brg1. in Molecular and cellular neurosciences 2014 (PubMed)

  3. Human Monoclonal SRGAP1 Primary Antibody for IF, ELISA - ABIN528215 : Hwang, Kohl, Fan, Vivante, Chan, Dworschak, Schulz, van Eerde, Hilger, Gee, Pennimpede, Herrmann, van de Hoek, Renkema, Schell, Huber, Reutter, Soliman, Stajic, Bogdanovic, Kehinde, Lifton, Tasic, Lu et al.: Mutations of the SLIT2-ROBO2 pathway genes SLIT2 and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract. ... in Human genetics 2015 (PubMed)

  4. Cow (Bovine) Polyclonal SRGAP1 Primary Antibody for WB - ABIN611096 : Boyd, Malstrom, Subramanian, Venkatesh, Schaeper, Elangovan, DSa-Eipper, Chinnadurai: Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. in Cell 1994 (PubMed)
    Show all 2 Pubmed References

More Antibodies against SRGAP1 Interaction Partners

Human SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) interaction partners

  1. we identified a consistently replicated loci at 12q14.2 (rs11175194 in SRGAP1, P(meta) = 1.14 x 10(-7))

  2. Mutations of the SLIT2 (show SLIT3 Antibodies)-ROBO2 (show ROBO2 Antibodies) pathway genes SLIT2 (show SLIT3 Antibodies) and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract

  3. The elevated miR (show MLXIP Antibodies)-145 present in invasive glioblastoma cells (IM3 cells) targets and down-regulated srGAP1, thereby allowing downstream G-proteins to remain in their active state and promote the observed invasive phenotype

  4. The interaction of betaPix (show ARHGEF7 Antibodies) with srGAP1 is critical for maintaining suppressive crosstalk between Cdc42 (show CDC42 Antibodies) and RhoA (show RHOA Antibodies) during 3D collagen migration.

  5. Data indicate that srGAP1 possesses a GAP activity specific to Rac1 and is recruited to lamellipodia in a Rac1-dependent manner.

  6. genome-wide linkage analysis in populations in Ohio and Poland: Data suggest that missense mutations in SRGAP1 are associated with genetic predisposition to papillary thyroid carcinoma.

  7. This study proposed that the expression of SRGAP1 in the anterior neocortex may mark the early location of the human motor cortex, including its corticospinal projection neurons, allowing further study of their early differentiation.

  8. FNBP2, ARHGAP13, ARHGAP14 and ARHGAP4 constitute the FNBP2 family characterized by FCH, RhoGAP and SH3 domains.

Mouse (Murine) SLIT-ROBO rho GTPase Activating Protein 1 (SRGAP1) interaction partners

  1. Mutations of the SLIT2 (show SLIT2 Antibodies)-ROBO2 (show ROBO2 Antibodies) pathway genes SLIT2 (show SLIT2 Antibodies) and SRGAP1 confer risk for congenital anomalies of the kidney and urinary tract

  2. srGAP1 and srGAP3 (show SRGAP3 Antibodies) are largely expressed in subpopulations of dorsal root ganglion neurons following sciatic nerve lesion.

  3. Data show that srGAP3 (show SRGAP3 Antibodies) is expressed in ventricular zones of neurogenesis in many different tissues of the central nervous system.

SRGAP1 Antigen Profile

Protein Summary

GTPase-activating protein for RhoA and Cdc42 small GTPases. Together with CDC42 seems to be involved in the pathway mediating the repulsive signaling of Robo and Slit proteins in neuronal migration. SLIT2, probably through interaction with ROBO1, increases the interaction of SRGAP1 with ROBO1 and inactivates CDC42.

Gene names and symbols associated with SRGAP1

  • SLIT-ROBO Rho GTPase activating protein 1 (SRGAP1) antibody
  • SLIT-ROBO Rho GTPase activating protein 1 (srgap1) antibody
  • SLIT-ROBO Rho GTPase activating protein 1 (Srgap1) antibody
  • 4930572H05Rik antibody
  • Arhgap13 antibody
  • RGD1566260 antibody

Protein level used designations for SRGAP1

SLIT-ROBO Rho GTPase-activating protein 1 , SLIT-ROBO Rho GTPase activating protein 1 , SLIT-ROBO Rho GTPase-activating protein 1-like , rho GTPase-activating protein 13 , Rho GTPase activating protein 13 , Rho GTPase activating protein

GENE ID SPECIES
100051440 Equus caballus
452043 Pan troglodytes
100398023 Callithrix jacchus
100483353 Ailuropoda melanoleuca
100485190 Xenopus (Silurana) tropicalis
100584408 Nomascus leucogenys
57522 Homo sapiens
117600 Mus musculus
417821 Gallus gallus
481144 Canis lupus familiaris
100623414 Sus scrofa
539452 Bos taurus
314903 Rattus norvegicus
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