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anti-SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antibodies

The protein encoded by SMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. Additionally we are shipping SMAD, Mothers Against DPP Homolog 1 Kits (54) and SMAD, Mothers Against DPP Homolog 1 Proteins (21) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SMAD1 4086 Q15797
SMAD1 17125 P70340
SMAD1 25671  
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Top anti-SMAD, Mothers Against DPP Homolog 1 Antibodies at antibodies-online.com

Showing 10 out of 311 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SMAD1 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate WB Suggested Anti-SMAD1  Antibody Titration: 0.2-1 µg/mL  Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB SMAD1 Antibody - N-terminal region (ARP38692_T100) validated by WB using Transfected 293T cell lysate at 2.41 µg/ul. 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SMAD1 Antibody Titration: 0.625ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-SMAD1  Antibody Titration: 0.625 µg/mL ELISA Titer: 1:1562500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Bonobo Rabbit Un-conjugated EIA, WB 25 μL Log in to see 6 to 8 Days
$253.00
Details
Bonobo Rabbit Un-conjugated EIA, WB 25 μL Log in to see 6 to 8 Days
$253.00
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from COLO cells, treated with EGF 200ng/ml 30', using Smad1 (Ab-465) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human heart tissue, using Smad1 (Ab-465) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB Western blot analysis of extracts from Jurkat/K562 cells, using Smad1 (Ab-187) Antibody. The lane on the right is treated with the synthesized peptide. Immunofluorescence analysis of HeLa cells, using Smad1 (Ab-187) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot analysis of extracts from HeLa cells, using Smad1/5/9 Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Mouse Un-conjugated IF, WB Immunofluorescence of monoclonal antibody to SMAD1 on HeLa cell (antibody concentration 10 µg/mL). SMAD1 monoclonal antibody (M02), clone 1D3 Western Blot analysis of SMAD1 expression in IMR-32. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated IF, WB 0.1 mL Log in to see 6 to 8 Days
$308.00
Details

SMAD1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-SMAD, Mothers Against DPP Homolog 1 Antibodies

  1. Human Monoclonal SMAD1 Primary Antibody for IF, WB - ABIN393492 : Jugessur, Shi, Gjessing, Lie, Wilcox, Weinberg, Christensen, Boyles, Daack-Hirsch, Nguyen, Christiansen, Lidral, Murray: Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. in PLoS ONE 2010 (PubMed)
    Show all 5 references for ABIN393492

  2. Human Polyclonal SMAD1 Primary Antibody for IF, WB - ABIN319351 : Li, Xin, Xu, Huang, Zhang, Chen, Zhang, Fu, Chang: CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription. in Molecular and cellular biology 2003 (PubMed)
    Show all 3 references for ABIN319351

  3. Human Polyclonal SMAD1 Primary Antibody for IF, ELISA - ABIN1532647 : Liu, Hata, Baker, Doody, Cárcamo, Harland, Massagué: A human Mad protein acting as a BMP-regulated transcriptional activator. in Nature 1996 (PubMed)
    Show all 2 references for ABIN1532647

  4. Chicken Polyclonal SMAD1 Primary Antibody for WB - ABIN2779411 : Blount, Merlie: BIP associates with newly synthesized subunits of the mouse muscle nicotinic receptor. in The Journal of cell biology 1991 (PubMed)
    Show all 2 references for ABIN2779411

  5. Human Polyclonal SMAD1 Primary Antibody for ELISA, WB - ABIN1533926 : Hoodless, Haerry, Abdollah, Stapleton, OConnor, Attisano, Wrana: MADR1, a MAD-related protein that functions in BMP2 signaling pathways. in Cell 1996 (PubMed)
    Show all 2 references for ABIN1533926

  6. Bonobo Polyclonal SMAD1 Primary Antibody for EIA, WB - ABIN401466 : Sapkota, Alarcón, Spagnoli, Brivanlou, Massagué: Balancing BMP signaling through integrated inputs into the Smad1 linker. in Molecular cell 2007 (PubMed)

  7. Chicken Polyclonal SMAD1 Primary Antibody for WB - ABIN2780720 : Jadlowiec, Zhang, Li, Campbell, Sfeir: Extracellular matrix-mediated signaling by dentin phosphophoryn involves activation of the Smad pathway independent of bone morphogenetic protein. in The Journal of biological chemistry 2006 (PubMed)

More Antibodies against SMAD, Mothers Against DPP Homolog 1 Interaction Partners

Zebrafish SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. Data show that interplay of Smad1/5 and MAP kinase (show MAPK1 Antibodies) signaling system (ERK (show MAPK1 Antibodies) signalling) is essential for haemogenic endothelium-based haematopoietic stem cell emergence.

  2. this study uncovers that smad1 and smad9 (show SMAD9 Antibodies) act redundantly to each other downstream of smad5 (show SMAD5 Antibodies) to mediate ventral specification and to regulate embryonic myelopoiesis.

  3. that specificity of BMP signaling output, with respect to hematopoiesis, can be explained by differential functions of Smad1 and Smad5 (show SMAD5 Antibodies).

Fruit Fly (Drosophila melanogaster) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues.

  2. During development, synaptic pMad accumulation followed the arrival and clustering of ionotropic glutamate (show GRIN2A Antibodies) receptors at neuromuscular junction synapses.

  3. The actions of Brat at synapses are mediated through mothers against decapentaplegic (Mad), the signal transduction effector of the bone morphogenetic protein (BMP) signaling pathway.

  4. Mad has distinct signal transduction roles in the BMP (show TGFb Antibodies) and Wnt (show WNT4 Antibodies) pathways depending on its phosphorylation state.

  5. Yorkie (show YAP1 Antibodies) and Mad physically bind each other, and 410 bp minimal enhancer of bantam that responds to Yorkie:Mad in vivo and in cultured cells, was identified.

  6. Heterodimers of SAX and TKV play an important role in extending the BMP activity gradient by facilitating DPP diffusion and assisting GBB signaling through functional complexes with type II receptors.

  7. importin (show KPNA4 Antibodies)-beta11 function interacts with the bone morphogenic protein (show TGFb Antibodies) pathway to regulate a pool of phosphorylated mothers against decapentaplegic that must be present at the presynapse for its proper development and function

  8. Mad depletion or overexpression produced Wingless-like embryonic segmentation phenotypes

  9. The downstream transcription factor Mothers against dpp is essential for the normal structural and functional development of the Drosophila neuromuscular junction, a synapse that displays activity-dependent plasticity.

  10. dSmurf specifically targets phosphorylated MAD to proteasome-dependent degradation and regulates DPP (show TGFb Antibodies) signaling during development.

Human SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. The expression SMAD1 (show GARS Antibodies) protein showed a significant correlation with lung cancer differentiation and lymphatic metastasis (P < 0.05), but not with genders, ages, tumor sizes and histological types of lung cancer patients (P>0.05).

  2. Overexpression of Smad1 (show GARS Antibodies) is associated with prostate cancer.

  3. SMAD1 (show GARS Antibodies) signaling may be a key pathway contributing the pathogenesis of Cardio-facio-cutaneous syndrome during early development.

  4. Smad1 (show GARS Antibodies) elevation serves as a compensatory mechanism for p53 (show TP53 Antibodies) deficiency by potentiating the activation of p53 (show TP53 Antibodies) parallel pathways.

  5. Our data indicated that downregulation of miR (show MLXIP Antibodies)-26b in osteosarcoma elevated the levels of CTGF (show CTGF Antibodies) and Smad1 (show GARS Antibodies), facilitating osteosarcoma metastasis

  6. Smad1 (show GARS Antibodies) as a novel binding protein of KSHV latency-associated nuclear antigen (LANA). LANA interacted with and sustained BMP-activated p-Smad1 (show GARS Antibodies) in the nucleus and enhanced its loading on the Id promoters.

  7. adult human Sertoli cells assumed similar morphological features, stable global gene expression profiles and numerous proteins, and activation of AKT (show AKT1 Antibodies) and SMAD1 (show GARS Antibodies)/5 during long-period culture.

  8. balance between Smad1 (show GARS Antibodies)/5- and Smad2 (show SMAD2 Antibodies)/3-dependent signaling defines the outcome of the effect of TGF-beta (show TGFB1 Antibodies) on atherosclerosis where Smad1 (show GARS Antibodies)/5 is responsible for proatherogenic effects

  9. Data show that USP15 (show USP15 Antibodies) enhances BMP-induced phosphorylation of SMAD1 (show GARS Antibodies) by interacting with and deubiquitylating ALK3 (show BMPR1A Antibodies).

  10. urinary Smad1 (show GARS Antibodies) may be a potential diagnostic parameter for diabetic nephropathy and may be used to evaluate the severity of diabetic nephropathy

Mouse (Murine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. AHNAK (show AHNAK Antibodies) plays a crucial role in body fat accumulation by regulating adipose tissue development via interaction with the SMAD1 protein and can be involved in metabolic homeostasis

  2. Results show that Smad1-deficient mice exhibit enhanced neuronal survival and improved neurological recovery at 7 days after transient middle cerebral artery occlusion suggesting that Smad1-mediated signal pathway is involved in stroke pathophysiology.

  3. The study reveals a novel miR (show MLXIP Antibodies)-26a-GSK3beta (show GSK3b Antibodies)-Smad1 signaling pathway in the regulation of mammalian axon regeneration.

  4. Nondiabetic Smad1-Tg had normal kidney however, diabetes resulted in mesangial expansion, consistent with an increase in glomerular phosphorylated Smad1. Heterozygous Smad1 KO mice exhibit attenuated mesangial expansion in the diabetic condition.

  5. The findings demonstrate for the first time that KMUP-1 can promote osteoblast maturation and differentiation in vitro via BMP-2 (show BMP2 Antibodies)/Smad1/5/8 and Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathways.

  6. FLI1 (show FLI1 Antibodies) and GATA2 (show GATA2 Antibodies) are upstream regulators of SMAD1 and SMAD5 (show SMAD5 Antibodies) expression in endothelial cells.

  7. Data indicate that PDGF (show PDGFA Antibodies)-AA promotes mesenchymal stem cel migration via bone morphogenetic protein 2 (BMP2 (show BMP2 Antibodies))-smad proteins smad1/5/8 activation requires lysosome-mediated degradation of PDGF (show PDGFA Antibodies) alpha Receptor (PDGFRalpha).

  8. some pSMAD1/5 targets, like Gata3 (show GATA3 Antibodies), function specifically in transit amplifying cell lineage-progression.

  9. The effects of a soy-free diet on the risk of granulosa cell tumors in mice with conditional double knockout of Smad1 and Smad5 (show SMAD5 Antibodies) are reported.

  10. Data indicate Indian hedgehog (Ihh (show IHH Antibodies)) induces collagen type X COL10A1 (show COL10A1 Antibodies) expression and promotes its transcription through Runx2 (show RUNX2 Antibodies)/Smad1 interactions on a specific promoter region.

Xenopus laevis SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. interactions between miR (show MYLIP Antibodies)-26 and the Smad1 3'UTR (show UTS2R Antibodies) modulate Smad1 function in the establishment of axial patterning.

Cow (Bovine) SMAD, Mothers Against DPP Homolog 1 (SMAD1) interaction partners

  1. a detailed computational model for TGF-beta (show TGFB1 Antibodies) signalling that incorporates elements of previous models together with crosstalking between Smad1/5/8 and Smad2 (show SMAD2 Antibodies)/3 channels through a negative feedback loop dependent on Smad7 (show SMAD7 Antibodies).

SMAD, Mothers Against DPP Homolog 1 (SMAD1) Antigen Profile

Protein Summary

The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene names and symbols associated with SMAD1

  • SMAD family member 1 (smad1) antibody
  • SMAD family member 1 (SMAD1) antibody
  • MAD homolog 1 (Drosophila) (smad1) antibody
  • Mothers against dpp (Mad) antibody
  • SMAD family member 1 (Smad1) antibody
  • SMAD family member 1 (smad1-a) antibody
  • 2/23 antibody
  • AI528653 antibody
  • apg antibody
  • BSP-1 antibody
  • BSP1 antibody
  • c28 antibody
  • CG12399 antibody
  • dMad antibody
  • Dmel\\CG12399 antibody
  • E(zen)2 antibody
  • En(vvl) antibody
  • fb39h09 antibody
  • JV4-1 antibody
  • JV41 antibody
  • l(2)k00237 antibody
  • mad antibody
  • Madh1 antibody
  • Madr1 antibody
  • Mat antibody
  • MLP antibody
  • Mlp1 antibody
  • MusMLP antibody
  • p-Mad antibody
  • pMad antibody
  • pSmad antibody
  • Smad antibody
  • smad-1 antibody
  • smad1 antibody
  • wu:fb39h09 antibody
  • wu:fb97e04 antibody
  • xmad antibody
  • Xmad1 antibody
  • Xsmad1 antibody

Protein level used designations for SMAD1

MAD homolog 1 , SMAD, mothers against DPP homolog 1 , mothers against decapentaplegic homolog 1 , mothers against decapentaplegic-like protein 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , SMA- and MAD-related protein 1 , SMAD 1 , SMAD family member 1 , mothers against DPP homolog 1 , CG12399-PA , CG12399-PB , Mad-PA , Mad-PB , apang , mother against decapentaplegic , mothers against decapentaplegi , mothers against decapentaplegic , mothers against dpp , phospho-Smad , phosphoSmad , phosphorylated smad , MAD, mothers against decapentaplegic homolog 1 , Mad-related protein 1 , TGF-beta signaling protein 1 , transforming growth factor-beta signaling protein 1 , transforming growth factor-beta-signaling protein 1 , Smad 1 , dwarfin-A , dwf-A , mMad1 , mad-related protein 1 , mothers-against-DPP-related 1 , MAD homolog1 (mothers against decapentaplegic, Drosophila) , mothers against DPP , BMP pathway effector , BMP signal transducer Smad1 , Sma- and Mad-related protein 1

GENE ID SPECIES
493211 Xenopus (Silurana) tropicalis
574340 Macaca mulatta
30628 Danio rerio
33529 Drosophila melanogaster
4086 Homo sapiens
17125 Mus musculus
25671 Rattus norvegicus
379664 Xenopus laevis
395680 Gallus gallus
475456 Canis lupus familiaris
397016 Sus scrofa
540488 Bos taurus
450142 Pan troglodytes
100432108 Pongo abelii
100033850 Equus caballus
443229 Ovis aries
100341544 Oryctolagus cuniculus
100727257 Cavia porcellus
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