SP110 Nuclear Body Protein (SP110) ELISA Kits

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. Additionally we are shipping SP110 Nuclear Body Protein Antibodies (67) and SP110 Nuclear Body Protein Proteins (3) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human SP110 SP110 3431 Q9HB58
Anti-Mouse SP110 SP110 109032 Q8BVK9
Anti-Rat SP110 SP110 301570 Q3KRF1
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More ELISA Kits for SP110 Nuclear Body Protein Interaction Partners

Cow (Bovine) SP110 Nuclear Body Protein (SP110) interaction partners

  1. SP110 as a novel susceptibility gene for Mycobacterium avium subspecies paratuberculosis infection in cattle.

Human SP110 Nuclear Body Protein (SP110) interaction partners

  1. Using mouse models and genetic characteristics of human patients the role of SP110b was studied to determine its role in controlling host immunity and susceptibility to TB by modulating nuclear factor-kappaB (NF-kappaB (show NFKB1 ELISA Kits)) activity resulting in down regulation of TNF-alpha (show TNF ELISA Kits) production and upregulation of NF-kappaB (show NFKB1 ELISA Kits)-induced antipoptotic gene expression suppressing IFN-gamma (show IFNG ELISA Kits)-mediated monocyte and/or macrophage cell death.

  2. The results indicated that both the heterozygous genotype GC and homozygous genotype CC in rs3809849 in MYBBP1A (show MYBBP1A ELISA Kits) had significant effects on the risk of pulmonary tuberculosis, and heterozygous genotype CT in rs9061 in SP110 also had similar effects.

  3. Results show that SP110 variants were associated with increased susceptibility to both pulmonary and extra-pulmonary tuberculosis in the Vietnamese patients. Those variants may influence macrophage signaling responses and apoptosis during the infection.

  4. Study suggests that a combination of SP110 and MYBBP1A gene polymorphisms may serve as a novel marker for identifying the risk of developing TB in the Chinese Han population.

  5. Several SNPs in Sp110 are risk factors for susceptibility to tuberculosis in Chongqing Han People.

  6. In a pooled analysis of 10,624 cases of tuberculosis, there was not a significant association between polymorphisms in the SP110 gene and disease susceptibility. [Meta-analysis]

  7. Genotyped 20 SNPs located in the SP110 gene, for the first time in a South East Asian cohort from Indonesia.Our study did not reveal any statistically significant associations between SP110 SNPs and pulmonary TB.

  8. a range of mutations in SP110 that cause decreased SP110 protein levels and impaired late B-cell differentiation cause veno-occlusive disease with immunodeficiency syndrome.

  9. the results might indicate a role of SP110 variants in extrapulmonary tuberculosis rather than PTB (show PTBP1 ELISA Kits).

  10. This study demonstrates that genotypes and haplotypes of SP110 might be associated with susceptibility to tuberculosis in Chinese population.

Mouse (Murine) SP110 Nuclear Body Protein (SP110) interaction partners

  1. mechanistic studies revealed that an arginine/lysine-rich element within the DNA-binding domain (SAND domain) is critical for Ipr1 binding to the importin (show KPNA4 ELISA Kits) protein receptor NPI-1 (show KPNA1 ELISA Kits), demonstrating that this element plays an essential role in mediating the nuclear localization of Ipr1 protein

  2. Using mouse models and genetic characteristics of human patients the role of SP110b was studied to determine its role in controlling host immunity and susceptibility to TB by modulating nuclear factor-kappaB (NF-kappaB (show NFKB1 ELISA Kits)) activity resulting in down regulation of TNF-alpha (show TNF ELISA Kits) production and upregulation of NF-kappaB (show NFKB1 ELISA Kits)-induced antipoptotic gene expression suppressing IFN-gamma (show IFNG ELISA Kits)-mediated monocyte and/or macrophage cell death.

  3. These findings not only reveal the transcriptional basis of Sp110-mediated macrophage resistance to Mtb (show NCAPG2 ELISA Kits), but also suggest potential regulatory roles for Sp110 related to inflammatory responses, miRNA profiles, and the intracellular growth of Mtb (show NCAPG2 ELISA Kits).

  4. Ipr1 might be involved in apoptosis pathway via MYBBP1A (show MYBBP1A ELISA Kits).

  5. identification and analysis of the genes Sp100 (show SP100 ELISA Kits), Csprs, and Ifi75 in two members of the genus Mus (show TRPV6 ELISA Kits), M. musculus and M. caroli

  6. data indicate that the Ipr1 gene product might have a previously undocumented function in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death and pathogenesis

SP110 Nuclear Body Protein (SP110) Antigen Profile

Antigen Summary

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Gene names and symbols associated with SP110

  • SP110 nuclear body protein (SP110) antibody
  • Sp110 nuclear body protein (Sp110) antibody
  • SP110 nuclear body protein (Sp110) antibody
  • 52kDa antibody
  • 5031415C07Rik antibody
  • 5830484A20Rik antibody
  • ENSMUSG00000075603 antibody
  • IFI41 antibody
  • Ifi75 antibody
  • Ipr1 antibody
  • SP110 antibody
  • VODI antibody

Protein level used designations for SP110

SP110 nuclear body protein , sp110 nuclear body protein-like , interferon-induced protein 41, 30kD , interferon-induced protein 41/75 , interferon-induced protein 75, 52kD , phosphoprotein 41 , phosphoprotein 75 , sp110 nuclear body protein , speckled 110 kDa , transcriptional coactivator Sp110 , intracellular pathogen resistance 1 , intracellular pathogen resistance protein 1

GENE ID SPECIES
470728 Pan troglodytes
515204 Bos taurus
100056977 Equus caballus
100391349 Callithrix jacchus
100452909 Pongo abelii
100585660 Nomascus leucogenys
3431 Homo sapiens
100686387 Canis lupus familiaris
109032 Mus musculus
301570 Rattus norvegicus
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