Use your antibodies-online credentials, if available.
No Products on your Comparison List.
Your basket is empty.
Find out more
SPEG encodes a protein with similarity to members of the myosin light chain kinase family. Additionally we are shipping SPEG Proteins (7) and many more products for this protein.
Showing 10 out of 16 products:
Human Polyclonal SPEG Primary Antibody for ELISA, WB - ABIN4281054
Hsieh, Yoshizumi, Endege, Kho, Jain, Kashiki, de los Santos, Lee, Perrella, Lee: APEG-1, a novel gene preferentially expressed in aortic smooth muscle cells, is down-regulated by vascular injury. in The Journal of biological chemistry 1996
Human Polyclonal SPEG Primary Antibody for IHC, IHC (p) - ABIN4281053
Agrawal, Pierson, Joshi, Liu, Ravenscroft, Moghadaszadeh, Talabere, Viola, Swanson, Haliloğlu, Talim, Yau, Allcock, Laing, Perrella, Beggs: SPEG interacts with myotubularin, and its deficiency causes centronuclear myopathy with dilated cardiomyopathy. in American journal of human genetics 2014
SPEG is present in cardiac muscle, where it plays a critical role; therefore, individuals with SPEG mutations additionally present with dilated cardiomyopathy.
Genomic rearrangement on APEG1 in arteriosclerosis was studied.
the RGD motif might play a role not only in the adhesion of Aortic Preferentially Expressed Protein-1 and extracellular proteins but also in intracellular protein (show CKAP2 Antibodies)-protein interactions
Acute loss of SPEG in hearts causes junctophilin-2 (show JPH2 Antibodies) de-phosphorylation leading to heart failure.
Disruption of the striated (show NSDHL Antibodies) preferentially expressed gene (Speg) locus leads to cardiac dysfunction and a phenotype consistent with dilated cardiomyopathy.
This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies in mouse have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants have been reported for this gene, but the full-length nature of only two variants that encode different protein isoforms has been defined.
aortic preferentially expressed gene 1
, novel serine/threonine protein kinase
, striated muscle preferentially expressed protein kinase
, aortic preferentially expressed protein 1
, nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury
, striated muscle-specific serine/threonine-protein kinase