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SRSF Protein Kinase 1 Proteins (SRPK1)

SRPK1 encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. Additionally we are shipping SRSF Protein Kinase 1 Antibodies (116) and SRSF Protein Kinase 1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SRPK1 20815 O70551
SRPK1 6732 Q96SB4
Rat SRPK1 SRPK1 361811  
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Top SRSF Protein Kinase 1 Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Baculovirus infected Insect Cells Human His tag,GST tag 50 μg Log in to see 16 Days
$272.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Baculovirus infected Insect Cells Human GST tag   5 μg Log in to see 10 to 12 Days
$322.08
Details

SRPK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
, ,

Top referenced SRSF Protein Kinase 1 Proteins

  1. Human SRPK1 Protein expressed in Baculovirus infected Insect Cells - ABIN2005139 : Choudhary, Kumar, Gnad, Nielsen, Rehman, Walther, Olsen, Mann: Lysine acetylation targets protein complexes and co-regulates major cellular functions. in Science (New York, N.Y.) 2009 (PubMed)
    Show all 2 references for ABIN2005139

More Proteins for SRSF Protein Kinase 1 (SRPK1) Interaction Partners

Fruit Fly (Drosophila melanogaster) SRSF Protein Kinase 1 (SRPK1) interaction partners

  1. Mutation of the Srpk79D gene causes conspicuous accumulations of BRP (show GDF5 Proteins) in larval and adult nerves.

  2. SRPK79D is a novel T-bar-associated protein kinase (show CDK7 Proteins) that represses T-bar assembly in peripheral axons, and that SRPK79D-dependent repression must be relieved to facilitate site-specific AZ assembly.

Mouse (Murine) SRSF Protein Kinase 1 (SRPK1) interaction partners

  1. In 2 independent murine models of breast tumor metastasis, stable shRNA-based SRPK1 knockdown suppressed metastasis to distant organs, including lung, liver, and spleen, and inhibited focal adhesion reorganization.

  2. SRPK1 overexpression is also tumorigenic because excess SRPK1 squelches PHLPP1.

  3. SRPK1 expression might be an important prognostic indicator for the chemoresponsiveness of nonseminomatous male germ cell tumors.

Human SRSF Protein Kinase 1 (SRPK1) interaction partners

  1. SRPK1 is upregulated in prostate cancer and correlates with disease stage and invasion.

  2. Data indicate serine/arginine-rich protein (show MANF Proteins) kinases SRPK1/2/SRPIN340 complexes by molecular docking and molecular dynamics.

  3. SRPK1 mediates TGF-beta (show TGFB1 Proteins)-induced proliferation.

  4. SRPK1 may be a potential anticancer target to inhibit glioma progression.

  5. Modulation of SRPK1 and subsequent inhibition of tumour angiogenesis.

  6. SRPK1 is a regulator of Tra2beta1 splicing function and individual domains engage in considerable cross-talk, assuming novel functions with regard to RNA binding, splicing, and catalysis.

  7. SRPK1 was highly expressed in basal breast cancer. High SRPK1 expression correlated with poor breast cancer disease outcome and preferential metastasis to the lungs and brain.

  8. Increased expression of SRPK1 correlates with the progression of breast cancer.SRPK1 is upregulated in breast cancer at both mRNA and protein levels.

  9. Data suggest that proline phosphorylation by CLK1/CDC-like kinase 1 (but not by SRPK1/serine/arginine-rich splicing factor kinase 1) regulates conformation and alternative splicing function of SFRS1 (serine/arginine-rich splicing factor 1 (show SRSF1 Proteins)).

  10. Collectively, these data suggest that human papillomavirus type 1 E1;E4-mediated inhibition of SRPK1 could affect the functions of host serine-arginine proteins and those of the virus transcription/replication regulator E2.

SRSF Protein Kinase 1 (SRPK1) Protein Profile

Protein Summary

This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. Alternative splicing of this gene results in multiple transcript variants. Additional alternatively spliced transcript variants have been described for this gene, but their full length nature have not been determined.

Gene names and symbols associated with SRSF Protein Kinase 1 Proteins (SRPK1)

  • SRSF protein kinase 1 (SRPK1)
  • serine-arginine protein kinase at 79D (srpk79D)
  • serine/arginine-rich protein specific kinase 1a (srpk1a)
  • serine/arginine-rich protein specific kinase 1 (Srpk1)
  • SRSF protein kinase 1 (Srpk1)
  • atc protein
  • AU017960 protein
  • BEST:CK01209 protein
  • CG9085 protein
  • CG11489 protein
  • CK01209 protein
  • Dmel\\CG11489 protein
  • SFRSK1 protein
  • SRPK protein
  • srpk1 protein
  • Srpk79D protein
  • wu:fc06h03 protein
  • zgc:63789 protein

Protein level used designations for SRSF Protein Kinase 1 Proteins (SRPK1)

CG11489-PB , CG11489-PE , CG11489-PF , CG11489-PH , CG11489-PI , CG11489-PJ , CG11489-PK , CG11489-PL , CG11489-PM , CG11489-PN , CG11489-PO , air traffic controller , srpk79D-PB , srpk79D-PE , srpk79D-PF , srpk79D-PH , srpk79D-PI , srpk79D-PJ , srpk79D-PK , srpk79D-PL , srpk79D-PM , srpk79D-PN , srpk79D-PO , serine/arginine-rich protein specific kinase 1 , SRSF protein kinase 1 , SFRS protein kinase 1 , SR protein-specific kinase 1 , SR-protein-specific kinase 1 , serine/arginine-rich protein-specific kinase 1 , serine/threonine-protein kinase SRPK1 , serine/arginine-rich splicing factor kinase 1 , Serine/threonine-protein kinase SRPK1

GENE ID SPECIES
100063400 Equus caballus
40461 Drosophila melanogaster
323679 Danio rerio
100593994 Nomascus leucogenys
20815 Mus musculus
6732 Homo sapiens
361811 Rattus norvegicus
474887 Canis lupus familiaris
100155422 Sus scrofa
512631 Bos taurus
100172042 Pongo abelii
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