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This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX1 Kits (26) and SOX1 Proteins (8) and many more products for this protein.
Showing 10 out of 61 products:
Human Polyclonal SOX1 Primary Antibody for FACS, WB - ABIN655709
Panayi, Panayiotou, Orford, Genethliou, Mean, Lapathitis, Li, Xiang, Kessaris, Richardson, Malas: Sox1 is required for the specification of a novel p2-derived interneuron subtype in the mouse ventral spinal cord. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2010
Show all 3 references for ABIN655709
Human Polyclonal SOX1 Primary Antibody for WB - ABIN610633
Alahari, Lee, Juliano: Nischarin, a novel protein that interacts with the integrin alpha5 subunit and inhibits cell migration. in The Journal of cell biology 2001
Show all 2 references for ABIN610633
Human Polyclonal SOX1 Primary Antibody for WB - ABIN610634
Sottile, Hocking: Fibronectin polymerization regulates the composition and stability of extracellular matrix fibrils and cell-matrix adhesions. in Molecular biology of the cell 2002
Show all 2 references for ABIN610634
Human Polyclonal SOX1 Primary Antibody for ELISA, WB - ABIN238657
Kan, Israsena, Zhang, Hu, Zhao, Jalali, Sahni, Kessler: Sox1 acts through multiple independent pathways to promote neurogenesis. in Developmental biology 2004
Chicken Polyclonal SOX1 Primary Antibody for WB - ABIN2780735
Sabater, Titulaer, Saiz, Verschuuren, Güre, Graus: SOX1 antibodies are markers of paraneoplastic Lambert-Eaton myasthenic syndrome. in Neurology 2008
The a (show SOX10 Antibodies)nalysis identified a signaling axis between FGF signaling and the transcription factor Sox1, which is preferentially expressed in stem- and mesenchymal-like breast cancers.
downregulation of SOX-1 was correlated with poor prognosis and tumor development in hepatocellular carcinoma.
SOX 1 suppressed cell growth and invasion in Tu212 cells by inhibiting Wnt (show WNT2 Antibodies) pathway, and the anti-tumor effect of SOX 1 could be weakened by SOX 2 (show SOX2 Antibodies), which may be a potential molecular basis for clinical treatment of laryngeal squamous cell carcinoma .
Our results suggest that SOX1 is epigenetically silenced in the majority of NSCLC and restoration of SOX1 inhibited cell migration by regulating actin cytoskeletal remodeling in NSCLC.
SOX1 decreases the expression of beta-catenin (show CTNNB1 Antibodies) in a proteasome-independent manner.
PAX1 (show PAX1 Antibodies) and SOX1 DNA methylation (show HELLS Antibodies) correlate with a cervical intraepithelial neoplasia diagnosis.
we successfully established a three-step inducing protocol to derive Neural stem cells from adipose-derived mesenchymal stem cells with high purity by Sox1 activation
The methylation index of SOX1 recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls.
Taken together, these data suggest that SOX1 can function as a tumor suppressor partly by interfering with Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling in cervical cancer.
Inactivation of SOX1 gene is associated with cisplatin resistance in human non-small cell lung cancer cell.
Continuous expression of Sox1 and Sox2 (show SOX2 Antibodies) in transgenic embryos represses neuron differentiation and inhibits anterior development while increasing cell proliferation.
These results implicate Xenopus Sox1 in neurogenesis, especially brain and eye development.
These results demonstrate a novel role for SOX2 (show SOX2 Antibodies) in glial process outgrowth and adhesion, and provide new insights into the essential role Muller glia play in the development of retinal cytoarchitecture.
Sox10 (show SOX10 Antibodies) overexpression causes mammary cells to undergo a mesenchymal transition.
Sox1, a member of the SoxB1 family of transcription factors, is expressed in a subset of radial astrocytes
Data show that a neural crest cells (NCCs) population that is not derived from Sox1(+) dorsal neuroepithelial cells but are derived from Sox1(-) cells differentiate into a significant population of melanocytes in the skin.
Sox1 regulates the size of the cortical neural progenitor pool via suppression of neurogenic cell divisions.
Genetic fate mapping and loss-of-function analysis show that transcription factor Sox1 is expressed in, and required for, a third type of p2-derived interneuron, which has been named V2c.
Our results show that the Bergmann glia population expresses Sox1 during cerebellar development, and that these cells can be isolated and show stem cell characteristics in vitro, suggesting that they could hold a broader potential than previously thought.
These data integrate functional roles of neural patterning factors, Notch (show NOTCH1 Antibodies) signalling and SOX1 during gliogenesis.
SOX1 is essential for ventral telencephalic development
newly identified enhancer with Sox (show QSOX1 Antibodies) elements activates the alphaB-crystallin (show CRYAB Antibodies) promoter in the lens, although they are separated by the entire HSPB2 (show HSPB2 Antibodies) gene
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.
SRY-related HMG-box gene 1
, transcription factor SOX-1
, SRY-box containing protein
, sex determining region Y-box 1
, transcription factor Sox-1