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SRY (Sex Determining Region Y)-Box 1 Proteins (SOX1)

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX1 Antibodies (61) and SOX1 Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SOX1 6656 O00570
SOX1 20664  
SOX1    
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Top SOX1 Proteins at antibodies-online.com

Showing 8 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Rat His tag,T7 tag 100 μg Log in to see 11 to 13 Days
$897.60
Details
Yeast Pleurodeles waltl His tag   1 mg Log in to see 56 to 66 Days
$2,038.67
Details
Yeast Chicken His tag   1 mg Log in to see 56 to 66 Days
$3,023.17
Details
Yeast Xenopus laevis His tag   1 mg Log in to see 56 to 66 Days
$3,085.50
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$3,111.17
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

SOX1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,

Mouse (Murine)

Chicken

More Proteins for SRY (Sex Determining Region Y)-Box 1 (SOX1) Interaction Partners

Human SRY (Sex Determining Region Y)-Box 1 (SOX1) interaction partners

  1. The results of the SRY (show SRY Proteins) gene amplification of plasma DNA from pregnant women was the same as that of the amniocyte DNA

  2. The a (show SOX10 Proteins)nalysis identified a signaling axis between FGF signaling and the transcription factor Sox1, which is preferentially expressed in stem- and mesenchymal-like breast cancers.

  3. downregulation of SOX-1 was correlated with poor prognosis and tumor development in hepatocellular carcinoma.

  4. SOX 1 suppressed cell growth and invasion in Tu212 cells by inhibiting Wnt (show WNT2 Proteins) pathway, and the anti-tumor effect of SOX 1 could be weakened by SOX 2 (show SOX2 Proteins), which may be a potential molecular basis for clinical treatment of laryngeal squamous cell carcinoma .

  5. Our results suggest that SOX1 is epigenetically silenced in the majority of NSCLC and restoration of SOX1 inhibited cell migration by regulating actin cytoskeletal remodeling in NSCLC.

  6. SOX1 decreases the expression of beta-catenin (show CTNNB1 Proteins) in a proteasome-independent manner.

  7. PAX1 (show PAX1 Proteins) and SOX1 DNA methylation (show HELLS Proteins) correlate with a cervical intraepithelial neoplasia diagnosis.

  8. we successfully established a three-step inducing protocol to derive Neural stem cells from adipose-derived mesenchymal stem cells with high purity by Sox1 activation

  9. The methylation index of SOX1 recovered from scrapings of uterine cervix adenocarcinomas is significantly higher than in normal controls.

  10. Taken together, these data suggest that SOX1 can function as a tumor suppressor partly by interfering with Wnt (show WNT2 Proteins)/beta-catenin (show CTNNB1 Proteins) signaling in cervical cancer.

Xenopus laevis SRY (Sex Determining Region Y)-Box 1 (SOX1) interaction partners

  1. Continuous expression of Sox1 and Sox2 (show SOX2 Proteins) in transgenic embryos represses neuron differentiation and inhibits anterior development while increasing cell proliferation.

  2. These results implicate Xenopus Sox1 in neurogenesis, especially brain and eye development.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 1 (SOX1) interaction partners

  1. These results demonstrate a novel role for SOX2 (show SOX2 Proteins) in glial process outgrowth and adhesion, and provide new insights into the essential role Muller glia play in the development of retinal cytoarchitecture.

  2. Sox10 (show SOX10 Proteins) overexpression causes mammary cells to undergo a mesenchymal transition.

  3. Sox1, a member of the SoxB1 family of transcription factors, is expressed in a subset of radial astrocytes

  4. Data show that a neural crest cells (NCCs) population that is not derived from Sox1(+) dorsal neuroepithelial cells but are derived from Sox1(-) cells differentiate into a significant population of melanocytes in the skin.

  5. Sox1 regulates the size of the cortical neural progenitor pool via suppression of neurogenic cell divisions.

  6. Genetic fate mapping and loss-of-function analysis show that transcription factor Sox1 is expressed in, and required for, a third type of p2-derived interneuron, which has been named V2c.

  7. Our results show that the Bergmann glia population expresses Sox1 during cerebellar development, and that these cells can be isolated and show stem cell characteristics in vitro, suggesting that they could hold a broader potential than previously thought.

  8. These data integrate functional roles of neural patterning factors, Notch (show NOTCH1 Proteins) signalling and SOX1 during gliogenesis.

  9. SOX1 is essential for ventral telencephalic development

  10. newly identified enhancer with Sox (show QSOX1 Proteins) elements activates the alphaB-crystallin (show CRYAB Proteins) promoter in the lens, although they are separated by the entire HSPB2 (show HSPB2 Proteins) gene

SOX1 Protein Profile

Protein Summary

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. In mice, a similar protein regulates the gamma-crystallin genes and is essential for lens development.

Gene names and symbols associated with SOX1

  • SRY (sex determining region Y)-box 1 (SOX1)
  • SRY (sex determining region Y)-box 1 (sox1)
  • SRY-box containing gene 1 (Sox1)
  • BB176347 protein
  • Sox-1 protein
  • XlSox1 protein
  • xSox1 protein

Protein level used designations for SOX1

SRY-related HMG-box gene 1 , transcription factor SOX-1 , SRY-box containing protein , sex determining region Y-box 1 , transcription factor Sox-1

GENE ID SPECIES
6656 Homo sapiens
607464 Canis lupus familiaris
734174 Xenopus laevis
374240 Gallus gallus
618135 Bos taurus
20664 Mus musculus
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