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anti-SRY (Sex Determining Region Y)-Box 10 (SOX10) Antibodies

SOX10 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX10 Proteins (11) and SOX10 Kits (10) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SOX10 6663 P56693
SOX10 29361 O55170
SOX10 20665 Q04888
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Top anti-SOX10 Antibodies at antibodies-online.com

Showing 10 out of 204 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB SOX10 Antibody (Center) (ABIN652035) western blot analysis in mouse heart tissue lysates (15 µg/lane). This demonstrates the SOX10 antibody detected SOX10 protein (arrow). SOX10 Antibody (Center) (ABIN652035) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Mouse Un-conjugated IHC, ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC (p), WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-SOX10 Antibody Titration: .25ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rabbit Un-conjugated WB WB Suggested Anti-Sox10 Antibody Titration: 0.2-1 ug/mlPositive Control: SP2/0 cell lysate WB Suggested Anti-Sox10  Antibody Titration: 0.2-1 µg/mL  Positive Control: SP2/0 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Immunoperoxidase of monoclonal antibody to SOX10 on formalin-fixed paraffin-embedded human colon. [antibody concentration 1.5 ug/ml] Western Blot detection against Immunogen (36.52 KDa) . 100 μg Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$566.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$446.88
Details
Human Rabbit Un-conjugated ELISA, WB   50 μg Log in to see 8 to 10 Days
$507.83
Details

SOX10 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-SOX10 Antibodies

  1. Human Monoclonal SOX10 Primary Antibody for IHC (p), ELISA - ABIN520385 : Kim, Chang, Yeo, Haw, Kim: Histopathological study of the treatment of melasma lesions using a low-fluence Q-switched 1064-nm neodymium:yttrium-aluminium-garnet laser. in Clinical and experimental dermatology 2013 (PubMed)
    Show all 2 references for ABIN520385

  2. Human Monoclonal SOX10 Primary Antibody for IHC, ELISA - ABIN1724912 : Bannykh, Stolt, Kim, Perry, Wegner: Oligodendroglial-specific transcriptional factor SOX10 is ubiquitously expressed in human gliomas. in Journal of neuro-oncology 2006 (PubMed)
    Show all 2 references for ABIN1724912

  3. Human Polyclonal SOX10 Primary Antibody for IHC (p), WB - ABIN610607 : Hunt, Morimoto: Conserved features of eukaryotic hsp70 genes revealed by comparison with the nucleotide sequence of human hsp70. in Proceedings of the National Academy of Sciences of the United States of America 1985 (PubMed)
    Show all 2 references for ABIN610607

  4. Human Monoclonal SOX10 Primary Antibody for FACS, ELISA - ABIN1724911 : Shin, Vincent, Cuda, Xu, Kang, Kim, Taube: Sox10 is expressed in primary melanocytic neoplasms of various histologies but not in fibrohistiocytic proliferations and histiocytoses. in Journal of the American Academy of Dermatology 2012 (PubMed)
    Show all 2 references for ABIN1724911

  5. Human Polyclonal SOX10 Primary Antibody for IHC (p), WB - ABIN652035 : Li, Tsuneki, Krauthammer, Couture, Schwartz, Madri: Modulation of Sox10, HIF-1?, Survivin, and YAP by Minocycline in the Treatment of Neurodevelopmental Handicaps following Hypoxic Insult. in The American journal of pathology 2015 (PubMed)

More Antibodies against SOX10 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 10 (SOX10) interaction partners

  1. Despite the fact that the E248fs has a dominant-negative effect on SOX10, its reduced stability may down-regulate the transcription of MITF (show MITF Antibodies) and decrease the synthesis of melanin

  2. SOX10-positivity rules out the diagnosis of ependymoma among other glial tumors with high confidence

  3. SOX-10 expression is exclusively specific for all cases of metastatic melanoma.

  4. Our study shows an inversed preferential nuclear expression of SLUG (show SNAI2 Antibodies), SOX10, and SOX9 (show SOX9 Antibodies) in triple negative and non-triple negative cases.

  5. SOX10 mutations can mimic non-syndromic hearing impairment.

  6. our data imply that the same SOX10 mutations can underlie both typical Waardenburg syndrome and Kallmann Syndrome with deafness without skin/hair hypopigmentation, Hirschsprung disease, or neurological defects

  7. Subnuclear re-localization of SOX10 and p54NRB (show NONO Antibodies) correlates with a unique neurological phenotype associated with SOX10 missense mutations.

  8. Our result confirm the thesis that heterozygous deletions at SOX10 is an important pathogenicity for Waardenburg syndrome type II.

  9. The use of SOX10 may increase the diagnostic accuracy of salivary gland oncocytic lesions on fine needle aspiration.

  10. Study shows that by uncoupling the effects of gain-of-function and haploinsufficiency in vivo, the effect of PCWH-causing SOX10 mutation is solely pathogenic in each SOX10-expressing cellular lineage in a dosage-dependent manner.

Xenopus laevis SRY (Sex Determining Region Y)-Box 10 (SOX10) interaction partners

  1. The activity of Sox-10 transcription factor is well conserved and is regulated by SUMOylation.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 10 (SOX10) interaction partners

  1. Kaiso (show ZBTB33 Antibodies) and Sox10 sequentially interact with Tcf7l2 (show TCF7L2 Antibodies) to coordinate the maturation of oligodendrocyte.

  2. Findings uncover a central role of SOX10 as a global regulator of gene expression in the melanocyte lineage by targeting diverse regulatory pathways.

  3. Ets1 (show ETS1 Antibodies) and Sox10 interact to promote proper melanocyte and enteric ganglia development from the neural crest.

  4. Sox10(rtTA/+) driven reporter expression in the cochlea persists for at least 54 days after cessation of neonatal induction

  5. Disrupted SOX10 function causes spongiform neurodegeneration in gray tremor mice.

  6. Our findings provide proof-of-concept that Sox10 can convert conducive cells into oligodendrocyte-like cells in vivo and delineates options for future therapeutic strategies.

  7. Conditional deletion of the neural crest specific transcription factor, Sox10, using the rhombic lip/neural crest specific Wnt1 (show WNT1 Antibodies)-cre driver spares Sox10 expression in the ear.

  8. This is strongly reminiscent of the situation in Schwann cells where Sox10 first induces and then cooperates with Krox20 (show EGR2 Antibodies) during myelination

  9. Decreases in Sox10 expression levels and a loss of Sox10(+) cells in both mouse and human aged ears suggests an important role of Sox10 in the maintenance of structural and functional integrity of the lateral wall.

  10. SOX10 continued to be expressed from the developmental stage to adulthood in the acinar and both luminal and abluminal intercalated ducts in the major salivary gland.

Zebrafish SRY (Sex Determining Region Y)-Box 10 (SOX10) interaction partners

  1. Demonstrate a contribution of sox10-dependent cranial neural crest to olfactory sensory neurons in zebrafish and provide important insights into the assembly of the nascent olfactory system.

  2. Data indicate that the optical flow analysis detected and quantified significant differences in the cell migrations of Sox10:EGFP positive cranial neural crest cells in ethanol treated versus untreated embryos.

  3. Sox10 might not be required for neural crest formation but is important for later steps during neural crest development.

  4. prdm1a (show PRDM1 Antibodies) Regulates sox10 and islet1 (show ISL1 Antibodies) in the development of neural crest and Rohon-Beard sensory neurons.

  5. Sox10 function is necessary for the survival of myelinating oligodedrocytes subsequent to axon wrapping but is not required for the survival of nonmyelinating oligodendrocyte progenitor cells.

  6. Phox2b (show PHOX2B Antibodies) function is sox10-dependent in the developing enteric nervous system

  7. Decrement of function of foxd3 and/or sox10, two genes important for the development and specification of neural crest, resulted in a reduction and/or loss of GnRH cells of the midbrain, as well as a reduction in the number of terminal nerve GnRH cells.

  8. Data show that expression of Mitf (show MITF Antibodies) rescues pigmentation fully in zebrafish, but only partially in Sox10-mutant mice.

  9. Sox10 is expressed transiently in the sensory neuron lineage, and specifies sensory neuron precursors by regulating the proneural gene neurogenin1 (show NEUROG1 Antibodies).

  10. Sox10 has diverse roles in the otic vesicle that may be important in a zebrafish model for Waardenburg syndrome type IV

SOX10 Antigen Profile

Protein Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional activator after forming a protein complex with other proteins. This protein acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Gene names and symbols associated with SOX10

  • SoxE protein (soxE) antibody
  • SRY (sex determining region Y)-box 10 (SOX10) antibody
  • SRY (sex determining region Y)-box 10 (sox10) antibody
  • transcription factor sox10 (sox10) antibody
  • SRY (sex determining region Y)-box 10 (LOC100222412) antibody
  • SRY (sex determining region Y)-box 10 (Sox10) antibody
  • SRY-box containing gene 10 (Sox10) antibody
  • SRY-box containing gene 10 (sox10) antibody
  • cls/sox10 antibody
  • Dom antibody
  • PCWH antibody
  • SOX-10 antibody
  • SOX10 antibody
  • Sox21 antibody
  • soxE antibody
  • WS2E antibody
  • WS4 antibody
  • WS4C antibody
  • zgc:100757 antibody

Protein level used designations for SOX10

SoxE protein , SRY (sex determining region Y)-box 10 , transcription factor Sox-10 , transcription factor SOX-10-like , transcription factor sox10 , SRY-related HMG-box gene 10 , dominant megacolon, mouse, human homolog of , transcription factor SOX-10 , SRY-box containing gene 10 , Sry-boxntranscription factor, SOX-10 , cSOX10 , SRY-box 10 , transcription factor Sox10 , dominant megacolon , transcription factor SOX-M , cls , colorless , colourless , colourless/sox10 , golas , gos , sox10b

GENE ID SPECIES
445804 Ciona intestinalis
470206 Pan troglodytes
481258 Canis lupus familiaris
702319 Macaca mulatta
100054980 Equus caballus
100101700 Xenopus (Silurana) tropicalis
100354496 Oryctolagus cuniculus
100404951 Callithrix jacchus
100534551 Oreochromis niloticus
100222412 Taeniopygia guttata
6663 Homo sapiens
29361 Rattus norvegicus
395573 Gallus gallus
414903 Sus scrofa
398422 Xenopus laevis
20665 Mus musculus
140616 Danio rerio
Selected quality suppliers for anti-SOX10 (SOX10) Antibodies
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