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anti-SRY (Sex Determining Region Y)-Box 18 (SOX18) Antibodies

SOX18 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX18 Proteins (5) and SOX18 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SOX18 54345 P35713
SOX18 311723  
SOX18 20672 P43680
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Top anti-SOX18 Antibodies at antibodies-online.com

Showing 10 out of 39 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IF, IHC, WB WB Suggested Anti-SOX18  Antibody Titration: 0.2-1 µg/mL  Positive Control: Human heart 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-SOX18 Antibody Titration: 2.0ug/mlPositive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Cow Rabbit Un-conjugated WB Human Jurkat; WB Suggested Anti-SOX18 Antibody Titration: 2.0ug/ml. Positive Control: Jurkat cell lysate; SOX18 antibody - middle region in Human Jurkat cells using Western Blot 0.1 mg Log in to see 6 to 8 Days
$335.50
Details
Cow Rabbit Un-conjugated IHC (p), WB Human lymphatic endothelial; lymphatic endothelial cell tissue and primary (1/50 up to 1/500) secondary 1/200; SOX18 antibody - middle region in Human lymphatic endothelial cells using Immunofluorescence Human kidney; Rabbit Anti-SOX18 Antibody. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; SOX18 antibody - middle region in Human kidney cells using Immunohistochemistry 50 μg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated IHC, WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IHC (p), WB Human Uterus (formalin-fixed, paraffin-embedded) stained with SOX18 antibody ABIN364480 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Testis (formalin-fixed, paraffin-embedded) stained with SOX18 antibody ABIN364480 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IF, WB SOX18 Antibody (N-term)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SOX18 antibody detected the SOX18 protein (arrow). Fluorescent confocal image of Hela cell stained with SOX18 Antibody (N-term).Hela cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with SOX18 primary antibody (1:25, 1 h at 37℃). For secondary antibody, Alexa Fluor® 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37℃).Cytoplasmic actin was counterstained with Alexa Fluor® 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37℃). Nuclei were counterstained with DAPI (blue) (10 µg/ml, 10 min).SOX18 immunoreactivity is localized to Nucleus significantly. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC, ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details

SOX18 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
,
,
, , , , ,
Rat (Rattus)


Mouse (Murine)


Top referenced anti-SOX18 Antibodies

  1. Cow (Bovine) Polyclonal SOX18 Primary Antibody for IF, IHC - ABIN2777725 : García-Ramírez, Martínez-González, Juan-Babot, Rodríguez, Badimon: Transcription factor SOX18 is expressed in human coronary atherosclerotic lesions and regulates DNA synthesis and vascular cell growth. in Arteriosclerosis, thrombosis, and vascular biology 2005 (PubMed)
    Show all 3 references for ABIN2777725

  2. Cow (Bovine) Polyclonal SOX18 Primary Antibody for WB - ABIN2777726 : Irrthum, Devriendt, Chitayat, Matthijs, Glade, Steijlen, Fryns, Van Steensel, Vikkula: Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia. in American journal of human genetics 2003 (PubMed)

More Antibodies against SOX18 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 18 (SOX18) interaction partners

  1. The downregulation of SOX18 was found to significantly inhibit cell adhesion and invasion.

  2. NKD2 (show NKD2 Antibodies) inhibits SOX18 and MMP-2,7,9 expression and suppresses BGC823 cell xenograft growth. NKD2 (show NKD2 Antibodies) methylation may serve as a poor prognostic and chemo-sensitive marker in human gastric cancer. NKD2 (show NKD2 Antibodies) impedes gastric cancer metastasis by inhibiting SOX18.

  3. GLI1 (show GLI1 Antibodies) and GLI2 (show GLI2 Antibodies), but not GLI3 (show GLI3 Antibodies) are involved in the regulation of SOX18 gene expression in cervical carcinoma cell lines.

  4. we demonstrated that upregulation of SOX18 was associated with a poor outcome in hepatocellular carcinoma patients

  5. The genetic finding of a pathogenic SOX18 mutation enabled the diagnosis of the rare hypotrichosis-lymphedema-telangiectasia syndrome in our patient.

  6. A new, autosomal dominant condition combining hypotrichosis-lymphedema-telangiectasia syndrome with renal defects is associated with a novel truncating mutation in the SOX18 gene.

  7. SOX18 may be involved in the progression of Non small cell lung cancer.

  8. Data suggest that SOX18 transcription factor expression may serve as a marker for a poor prognosis in invasive ductal breast carcinoma.

  9. The repression of Sox18 and its target genes may lead to altered formation of vessels in inflamed settings.

  10. of the 679 gastric cancer cases, 177 (26.1%) were positive for SOX 18 expression in their tumor stroma, and the frequencies of both lymphovascular invasion and lymph node metastases were higher in the SOX 18 positive than in the negative group.

Pig (Porcine) SRY (Sex Determining Region Y)-Box 18 (SOX18) interaction partners

  1. Here we demonstrate that VEGF (show VEGFA Antibodies)-165 mediates MSC (show MSC Antibodies) differentiation into ECs via VEGFR-2 (show KDR Antibodies)-dependent induction of Sox18, which ultimately coordinates the transcriptional upregulation of specific markers of the EC phenotype

Mouse (Murine) SRY (Sex Determining Region Y)-Box 18 (SOX18) interaction partners

  1. combined deletion of Sox7 (show SOX7 Antibodies), Sox17 (show SOX17 Antibodies), and Sox18 at the onset of retinal angiogenesis leads to a dense capillary plexus with a nearly complete loss of radial arteries and veins, whereas the presence of a single Sox17 (show SOX17 Antibodies) allele largely restores arterial identity

  2. Sox18 genetically interacts with VegfC (show VEGFC Antibodies) to regulate lymphangiogenesis in Zebrafish.

  3. SOX18 induction is a key step in mediating tumor lymphangiogenesis and metastasis

  4. Overexpression of wild-type SOX18 promoted capillary tube formation of HUVECs in vitro, whereas expression of dominant-negative SOX18 impaired tube formation of HUVECs and the migration of MCF-7 cells via the disruption of the actin cytoskeleton.

  5. Results indicate that Sox17 (show SOX17 Antibodies) and Sox18, and possibly all three SoxF genes, are cooperatively involved in mammalian vascular development.

  6. These result can explain previously controversial data on the functional consequences of Sox18 mutations in mice and humans.

  7. Sox17 (show SOX17 Antibodies)/Sox18 double-null embryos showed more severe defects in formation of anterior dorsal aorta and head/cervical microvasculature, and in some cases, aberrant differentiation of endocardial cells and defective fusion of the endocardial tube

  8. findings demonstrate a critical role for Sox18 in developmental lymphangiogenesis, and suggest new avenues to investigate for therapeutic management of human lymphangiopathies

  9. SOX18 plays role in the vascular dysfunction in hypotrichosis-lymphedema-telangiectasia syndrome.

  10. SOX7 (show SOX7 Antibodies) and SOX17 (show SOX17 Antibodies) are not normally expressed during lymphatic development, excluding a conventional redundancy mechanism with SOX18. Instead, these genes are activated specifically in the absence of SOX18 function, and only in certain strains.

SOX18 Antigen Profile

Protein Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This protein plays a role in hair, blood vessel, and lymphatic vessel development. Mutations in this gene have been associated with recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia.

Gene names and symbols associated with SOX18

  • SRY (sex determining region Y)-box 18 (SOX18) antibody
  • SRY (sex determining region Y)-box 18 (Sox18) antibody
  • SRY-box containing gene 18 (Sox18) antibody
  • AI385749 antibody
  • HLTS antibody
  • Ra antibody
  • Ragl antibody

Protein level used designations for SOX18

SRY-box 18 , transcription factor SOX-18 , SRY-box containing gene 18 , Sry-related HMG-box gene 18 , ragged

GENE ID SPECIES
54345 Homo sapiens
100049667 Sus scrofa
519439 Bos taurus
311723 Rattus norvegicus
20672 Mus musculus
Selected quality suppliers for anti-SOX18 (SOX18) Antibodies
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