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anti-SRY (Sex Determining Region Y)-Box 3 (SOX3) Antibodies

SOX3 encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Additionally we are shipping SOX3 Kits (26) and SOX3 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SOX3 6658 P41225
SOX3 20675  
SOX3 367950  
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Top anti-SOX3 Antibodies at antibodies-online.com

Showing 10 out of 64 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated WB WB Suggested Anti-SOX3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:2500Positive Control: Raji cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SOX3 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Dog Goat Un-conjugated EIA, IHC (p), WB AP20177PU-N SOX3 Antibody staining of paraffin embedded Human Cerebral Cortex at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. AP20177PU-N SOX3 Antibody staining of Human Cerebral Cortex lysate at 0.5 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-SOX3 Antibody Titration: 1.25ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Chicken Rabbit Un-conjugated WB WB Suggested Anti-SOX3 Antibody Titration: 1.25ug/mlELISA Titer: 1:312500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated WB SOX3 Antibody (Center) (ABIN655392) western blot analysis in MDA-MB453,HL-60 cell line lysates (35 µg/lane). This demonstrates the SOX3 antibody detected the SOX3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, WB SOX3 Antibody (Center P204) (ABIN656009) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the SOX3 antibody detected the SOX3 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IHC (p), WB Human Brain, Cerebellum (formalin-fixed, paraffin-embedded) stained with SOX3 antibody ABIN214149 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details

SOX3 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)
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Rat (Rattus)
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Top referenced anti-SOX3 Antibodies

  1. Dog (Canine) Polyclonal SOX3 Primary Antibody for WB - ABIN2777860 : Raverot, Lejeune, Kotlar, Pugeat, Jameson: X-linked sex-determining region Y box 3 (SOX3) gene mutations are uncommon in men with idiopathic oligoazoospermic infertility. in The Journal of clinical endocrinology and metabolism 2004 (PubMed)

  2. Human Polyclonal SOX3 Primary Antibody for WB - ABIN2780698 : Savare, Bonneaud, Girard: SUMO represses transcriptional activity of the Drosophila SoxNeuro and human Sox3 central nervous system-specific transcription factors. in Molecular biology of the cell 2005 (PubMed)

  3. Dog (Canine) Polyclonal SOX3 Primary Antibody for EIA, IHC (p) - ABIN498075 : Mojsin, Stevanovic: PBX1 and MEIS1 up-regulate SOX3 gene expression by direct interaction with a consensus binding site within the basal promoter region. in The Biochemical journal 2009 (PubMed)

  4. Chicken Polyclonal SOX3 Primary Antibody for WB - ABIN2777861 : Bleyl, Byrne, South, Dries, Stevenson, Rope, Vianna-Morgante, Schoenwolf, Kivlin, Brothman, Carey: Brachymesomelic dysplasia with Peters anomaly of the eye results from disruptions of the X chromosome near the SHOX and SOX3 genes. in American journal of medical genetics. Part A 2007 (PubMed)

More Antibodies against SOX3 Interaction Partners

Human SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. SOX3 overdosage permits normal sex development in 46,XX individuals with random X inactivation.

  2. Translocations interrupting this region may also affect the gonadal development, possibly depending on the chromatin context of the recipient chromosome. SOX3 duplications may substitute SRY (show SRY Antibodies) in some XX subjects

  3. Screening for SOX3 should be advised not only for hypopituitary patients with an ectopic posterior pituitary, but also for those with a structurally normal pituitary

  4. Our study provides additional evidence that deletion in polyalanine tracts of SOX3 is associated with hypopituitarism

  5. SOX3 duplication is a genetic cause for XH but has incomplete penetrance. Moreover, increased SOX3 levels may be a risk factor for NTD and potentially other clinical characteristics.

  6. the results point at CREB (show CREB1 Antibodies) as a positive regulator of SOX3 gene transcription in NT2/D1 cells, while its contribution to RA induction of SOX3 promoter is not prominent.

  7. Overexpression of Sox3 is associated with esophageal squamous cell carcinoma.

  8. Data indicate that HESX1 (show HESX1 Antibodies), LHX4 (show LHX4 Antibodies) and SOX3 polymorphisms may be associated with pituitary stalk interruption syndrome (PSIS).

  9. Results indicate positive expression of SOX2, SOX3, PAX6, OCT3/4, and NANOG in the CD105+ and CD105(-) cell subpopulations.

  10. TGIF (TG-interacting factor (show TGIF1 Antibodies)) is an additional TALE superfamily member involved in the regulation of human SOX3 gene expression

Xenopus laevis SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. Sox2 (show SOX2 Antibodies) is necessary for spinal cord regeneration and suggest a model whereby spinal cord injury activates proliferation of Sox2 (show SOX2 Antibodies)/3 expressing cells and their differentiation into neurons, a mechanism that is lost in non-regenerative froglets.

  2. XSeb4R (show RBM38 Antibodies) protein bound specifically to the 3'UTR (show UTS2R Antibodies) of Sox3 mRNA. XSeb4R (show RBM38 Antibodies) gain-of-function in ectodermal explants revealed increased stability of the maternal Sox3 transcripts, associated with a robust Sox3 protein production.

  3. knockdown of Oct91 inhibits neural induction driven by either Sox2 (show SOX2 Antibodies) or Sox3.

  4. Animal pole localized Sox3 acts to inhibit Nodal (Xnr5 and Xnr6) expression, and induces the expression of genes (Ectodermin (show TRIM33 Antibodies), Xema (show FOXI1 Antibodies), and Coco (show DAND5 Antibodies)) whose products repress Nodal signaling.

  5. Results demonstrate that both sox3 and sox2 are induced in response to BMP antagonism, but by distinct mechanisms and that the activation of both genes is independent of FGF signaling; however, both require FGF for the maintenance of their expression.

  6. Eya1 (show EYA1 Antibodies) and Six1 (show SIX1 Antibodies) are required for both the regulation of placodal neuronal progenitor proliferation, through their effects on SoxB1 expression, and subsequent neuronal differentiation.

Mouse (Murine) SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. Sox3 null mice exhibit a ventral extension of the anterior pituitary that penetrates, and generates a mass beneath, the sphenoid bone

  2. These data define Dbx1 (show DBX1 Antibodies) as a direct SOX3 target gene.

  3. Sox2 (show SOX2 Antibodies) and Sox3 play a role in central nervous system glia and provide mechanistic insights into their function during differentiation processes.

  4. findings show SOX3 expression is maintained throughout telencephalic neurogenesis and is restricted to progenitor cells with neuroepithelial and radial glial morphologies; it is expressed within adult neurogenic regions; expression within the developing hypothalamus is upregulated in developing neurons and is maintained in a subset of differentiated hypoththalamic cells

  5. Subcommissural organ function is essential for the prevention of hydrocephalus and overexpression of Sox3 in the dorsal midline alters progenitor cell differentiation in a dose-dependent manner.

  6. It was shown that Sox2 (show SOX2 Antibodies) and Sox3 are dose-dependent regulators of sonic hedgehog (show SHH Antibodies) transcription that directly bind and activate a long-range Shh (show SHH Antibodies) forebrain enhancer.

  7. In neural precursor cells , Sox3 binds genes that are later bound and activated by Sox11 (show SOX11 Antibodies) in differentiating neurons (Sox2 (show SOX2 Antibodies))

  8. The results indicate that Sox3 functions in an intrinsic manner to promote differentiation of spermatogonia in prepubertal mice but it is not required for ongoing spermatogenesis in adults.

  9. in a transgenic line, Sox3 was ectopically expressed in the bipotential gonad and this led to frequent complete XX male sex reversal

  10. Sox3 is not required for gonadal determination but is important for normal oocyte development and male testis differentiation and gametogenesis.

Zebrafish SRY (Sex Determining Region Y)-Box 3 (SOX3) interaction partners

  1. significant decreases in sox3 (up to 3-fold) expression following chilling. Significant increases in expression of sox3 (up to 33-fold) during warming of chilled zebrafish embyos.

  2. Knockdown of fgf24 or sox3 causes severe epibranchial deficiencies but has little effect on otic development

  3. Knockdown of the four B1 sox (show PIPOX Antibodies) genes sox2 (show SOX2 Antibodies)/3/19a/19b resulted in severe developmental abnormalities.

  4. The pro-neural effects of Sox3 can compensate for inhibition of fibroblast growth factor (Fgf) signalling in inducing neural tissue but it is not sufficient to maintain neural fate, suggesting the presence of Sox3-independent roles of Fgf at later stages.

SOX3 Antigen Profile

Protein Summary

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency.

Gene names and symbols associated with SOX3

  • transcription factor SOX-3 (Tsp_06143) antibody
  • SRY (sex determining region Y)-box 3 (sox3) antibody
  • SRY (sex determining region Y)-box 3 (LOC100349101) antibody
  • SRY (sex determining region Y)-box 3 (LOC100349813) antibody
  • SRY (sex determining region Y)-box 3 (SOX3) antibody
  • SRY-box containing gene 3 (Sox3) antibody
  • SRY-box containing gene 3 (sox3) antibody
  • CH3 antibody
  • fc93f07 antibody
  • GHDX antibody
  • id:ibd2036 antibody
  • MRGH antibody
  • PHP antibody
  • PHPX antibody
  • sb:cb493 antibody
  • Sox-3 antibody
  • sox3-a antibody
  • SOXB antibody
  • Sry antibody
  • wu:fc93f07 antibody
  • wu:fd02a08 antibody
  • Xlsox3 antibody
  • xSox-B1 antibody
  • xSox3 antibody
  • Xtsox3 antibody
  • zgc:110279 antibody

Protein level used designations for SOX3

transcription factor SOX-3 , transcription factor Sox-3 , SRY (sex determining region Y)-box 3 , SRY-related protein CH3 , cSox3 , transcription factor SOX3 , transcription factor Sox-3-A , xSox3 , 2036

GENE ID SPECIES
10911545 Trichinella spiralis
493228 Xenopus (Silurana) tropicalis
100349101 Oryctolagus cuniculus
100349813 Oryctolagus cuniculus
6658 Homo sapiens
492178 Canis lupus familiaris
374019 Gallus gallus
399335 Xenopus laevis
781679 Bos taurus
20675 Mus musculus
367950 Rattus norvegicus
30529 Danio rerio
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